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ARBOVIRUSES – ENCEPHALITIS North America California serogroup (La Crosse etc) BUNYAVIRIDAE West US, Canada, Mexico, Brazil Western equine encephalitis East US, Canada Eastern equine encephalitis TOGAVIRIDAE North America St Louis encephalitis North America, parts of Europe, parts of Africa West Nile virus encephalitis FLAVIVIRIDAE DISTRIBUTION FAMILY
CALIFORNIA SEROGROUP ENCEPHALITIS (includes La Crosse virus)
Recently commoner in eastern US
Reservoir: small mammals
Children at higher risk
~80 cases/year av.
La Crosse life cycle 2000 - 2 cases in SC, Charleston area bunyavirus
ARBOVIRUSES – FEVER AND HEMORRHAGIC FEVER FAMILY FLAVIVIRIDAE Dengue Yellow fever REOVIRIDAE Colorado tick fever DISTRIBUTION World wide, especially tropics Africa, S. and C. America North America MAIN DISEASES fever, hemorrhagic fever hemorrhagic fever fever
WEST NILE VIRUS flavivirus http://www.cdc.gov/ncidod/dvbid/westnile/clinicians/epi.htm Table. Median age (in years) of development of West Nile illness following infection Year* Fever Meningitis Encephalitis (with or without associated meningitis) Death** 2002 49 46 64 78 2003 45 46 62 80 **Most deaths were among encephalitis patients.