National Institute of Allergy and Infectious Diseases, NIH


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National Institute of Allergy and Infectious Diseases, NIH

  1. 1. National Institute of Allergy and Infectious Diseases, NIH Grant Opportunities and Management Symposium Overview & Funding Opportunities Presented by Paula S. Strickland, Ph.D., MPH Director, Office of International Extramural Activities (OIEA) Division of Extramural Activities National Institute of Allergy and Infectious Diseases National Institutes of Health Department of Health and Human Services
  2. 2. NIAID Symposium <ul><li>Purpose </li></ul><ul><li>To provide information on funding opportunities; </li></ul><ul><li>Assist researchers and administrators in better understanding NIH funding policies and the peer review process; </li></ul><ul><li>To provide information on grants management. </li></ul>
  3. 3. Overview About NIH & NIAID Grant opportunities & resources Application process Advice on preparing your application budget Program: Scientific areas of interest Manage NIH grant funds Fundable grant Peer review process
  4. 4. NIH Consists of 27 Institutes and Centers Mission: To support biomedical and behavioral research for the public good. = Extramural only NEI NCI NHLBI NLM NINDS NIMH NIAMS NINR NCCAM CIT CC NHGRI NIA NIAAA NIAID NICHD NIDCD NIDCR NIDDK NIDA NIEHS OD NIGMS NCRR NIBIB NCMHD FIC CSR
  5. 5. NIAID <ul><li>Mission : “ To conduct and support research that strives to understand, treat, and ultimately prevent the multitude of infectious, immunologic, and allergic diseases that endanger the lives of millions of people nationally and globally.” </li></ul><ul><li>NIAID is the lead institute for infectious diseases and immunology research </li></ul><ul><li>Budget in FY 2007 is ~$4.3 billion </li></ul><ul><li>Received a large allocation in FY 2003 for biodefense research </li></ul>
  6. 7. NIAID Priorities <ul><li>To Develop: </li></ul><ul><li>An effective AIDS vaccine </li></ul><ul><li>Technologies and medical countermeasures against Cat A-C agents and emerging infectious diseases </li></ul><ul><li>New medical counter measures for influenza </li></ul><ul><li>Medical interventions using immune tolerance strategies </li></ul><ul><li>Better capacity in developing countries to support clinical trials of vaccines and therapeutics for AIDS, malaria, TB, and other important global diseases </li></ul>
  7. 8. NIAID Global Research Research Funded in over 100 countries
  8. 9. Emerging & Re-emerging Infectious Diseases <ul><li>NIAID supported research includes: </li></ul><ul><li>Basic </li></ul><ul><li>Applied </li></ul><ul><li>Clinical </li></ul>
  9. 10. Influenza <ul><li>Basic research </li></ul><ul><li>Diagnostics </li></ul><ul><li>Therapeutics </li></ul><ul><li>Pre-pandemic and Pandemic vaccines </li></ul>
  10. 11. Tuberculosis & Malaria <ul><li>Multi-drug resistant (MDR) forms of Mycobacterium tuberculosis </li></ul><ul><li>Extensively-drug resistant TB (XDR-TB), </li></ul><ul><li>Malaria </li></ul><ul><ul><li>Drugs </li></ul></ul><ul><ul><li>vaccines </li></ul></ul>
  11. 12. HIV/AIDS <ul><li>Pathogenesis </li></ul><ul><li>Therapy/Care </li></ul><ul><li>Prevention </li></ul><ul><li>Vaccines </li></ul>
  12. 13. Biodefense Research <ul><li>Three areas of focus: </li></ul><ul><li>Infrastructure – safely conduct research on dangerous pathogens </li></ul><ul><li>Basic research - microbes and host immune defenses </li></ul><ul><ul><li>foundation for applied research </li></ul></ul><ul><li>Medical countermeasures – targeted, milestone-driven </li></ul><ul><ul><li>vaccines, therapeutics, and diagnostics </li></ul></ul>
  13. 14. Immune-mediated Diseases <ul><li>Autoimmune and allergic diseases, asthma: </li></ul><ul><ul><li>Immune Tolerance therapies </li></ul></ul><ul><ul><li>Asthma treatment and drug studies </li></ul></ul>
  14. 15. The Search for Research Funds
  15. 16. Funding Information Resource: Internet <ul><li>Timely information and updates </li></ul><ul><li>Includes current and relevant information </li></ul><ul><li>Funding opportunities - grants, contracts </li></ul><ul><ul><li>policies, and other subjects of interest to applicants </li></ul></ul>
  16. 17. Search for Funding Sources
  17. 18. U.S. Grants & Funding Opportunities <ul><li> website : </li></ul><ul><li>Find grant opportunities </li></ul><ul><ul><li>26 Federal grant-making agencies </li></ul></ul><ul><li>Register </li></ul><ul><ul><li>Allows organization to apply for U.S. grants </li></ul></ul><ul><ul><li>Process in 3-5 business days (incomplete info causes delays) </li></ul></ul><ul><li>Apply for grants </li></ul><ul><li>Find electronic submission resources </li></ul><ul><li>Track your application </li></ul>
  18. 19. DHHS Funding Opportunities
  19. 20. NIH Funding Opportunities
  20. 21. Funding Opportunities <ul><li>NIH Guide for Grants and Contracts </li></ul><ul><ul><li>official publication listing NIH funding </li></ul></ul><ul><ul><li>policy notices </li></ul></ul><ul><li>Published weekly </li></ul><ul><li>List grants and contracts </li></ul><ul><ul><li>Request for Applications (RFA) </li></ul></ul><ul><ul><li>Program Announcements (PA) </li></ul></ul><ul><ul><li>Request for Proposals (RFP) </li></ul></ul>
  21. 22. Choose the Appropriate Funding Instrument and Mechanism <ul><li>Three major funding “instruments” to support extramural research </li></ul><ul><ul><li>Grant – researcher decides the research to be designed and approach </li></ul></ul><ul><ul><li>Contract – government decides the research to fill a specific need </li></ul></ul><ul><ul><li>Cooperative agreement – grant, but the awarding institute has substantial involvement in the project activities </li></ul></ul>
  22. 23. Submission Dates ( See NOT-OD-07-053 for change in AIDS receipt dates) Jan 7 Sept 7 May 7 Based on mechanism AIDS and AIDS-Related Applications new, renewal, resubmission, revision Oct 16 June 16 Feb 16 SF 424 Other research grants R03, R21 Oct 5 June 5 Feb 5 PHS 398 – transition to SF424 (on hold) Research Grant U01 new Oct 5 June 5 Feb 5 SF 424 Research Grant R01 new Cycle III Due Date Cycle II Due Date Cycle I Due Date Application Form Program Description Mecha-nism(s)
  23. 24.
  24. 25. NIAID Research Funding Opportunities <ul><li>Most RFA/PA - open to applicants from the private and public sectors, including small businesses. </li></ul><ul><li>Check the Eligibility section to see if Foreign organizations are eligible. </li></ul><ul><li>Read the complete RFA/PA for allowable costs </li></ul><ul><li>NIAID related opportunities </li></ul><ul><ul><li> </li></ul></ul>
  25. 27. Foundations and Other Funding Sources <ul><li>Grant funding organizations outside of NIH that cover the same areas of science as the NIAID Funding Opportunities List </li></ul><ul><li> </li></ul>
  26. 28. NIH Grant Process Peer review Fundable Score & NIAID portfolio <ul><li>Notice of Award (NoA) </li></ul><ul><li>Read NoA carefully </li></ul>Submit grant application
  28. 30. NIAID International Assistance for Funded Investigators <ul><li>Program officers – research questions </li></ul><ul><li>Grants management specialists – budget and allowable cost questions </li></ul><ul><li>NIAID contractor (OIEA managed)– onsite grant and contract financial management information and training. </li></ul>
  29. 31. New Independent Investigators Websites Shorter Review Cycle K99/R00 Award
  30. 32. New Investigator - Evolving Definition <ul><li>Yes : </li></ul><ul><li>Small Grant (R03) </li></ul><ul><li>Academic Research Enhancement Award (R15) </li></ul><ul><li>Exploratory/Developmental Grant Phase I (R21) -- except R21/R33 </li></ul><ul><li>Shannon Award (R55) </li></ul><ul><li>High-Priority, Short-Term Project (R56-Bridge) </li></ul><ul><li>Some career awards (K01, K08, K22, K23, K25, or K99/R00) </li></ul><ul><li>No : </li></ul><ul><li>R01 </li></ul><ul><li>R21/R33 </li></ul><ul><li>R29 (no longer awarded) </li></ul><ul><li>Other senior career awards (K02, K06, K24, and K26). </li></ul>
  31. 33. NIH K99/R00 Awards <ul><li>NIH K99/R00 </li></ul><ul><li>Transition award (postdoc-to asst. professor) </li></ul><ul><li>Up to 5 years </li></ul><ul><li>Up to 2 yr mentored phase ($90K/yr + 8% F&A costs) </li></ul><ul><li>Awardee becomes asst. professor </li></ul><ul><li>Up to 3 yr independent R phase ($249K/yr + 50% F&As) </li></ul>
  32. 34. NIAID “All About Grants Tutorial” Website
  33. 35. <ul><li>Websites </li></ul><ul><ul><li> </li></ul></ul><ul><ul><li> </li></ul></ul><ul><ul><li> </li></ul></ul>For More Information
  34. 36. Thank You <ul><ul><li>Paula S. Strickland, Ph.D., MPH </li></ul></ul><ul><ul><li>EMAIL: </li></ul></ul><ul><ul><li>Phone: (301) 435-8563 </li></ul></ul>