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LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION
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LSRO- DENTAL AMALGAM SCIENTIFIC REVIEW PANEL PRESENTATION

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  • 1. Goals For This Meeting <ul><li>Receive input and comment on the recent literature regarding the potential adverse health effects of dental amalgams (to the LSRO and the Expert Panel) </li></ul><ul><li>Provide background to Expert Panel </li></ul><ul><li>Report on the process and current thinking (to the stakeholder communities) </li></ul>
  • 2. Goals For This Project <ul><li>Identify and evaluate recent literature </li></ul><ul><li>Provide scientific, evidence-based opinion on the potential adverse health effects of dental amalgam </li></ul><ul><li>Not recommending public policy </li></ul>
  • 3. General Procedures <ul><li>Time frame: Summer 2003 – Spring 2004 </li></ul><ul><li>Call(s) for public comment </li></ul><ul><li>Selection of Expert Panel </li></ul><ul><li>Transparent process </li></ul><ul><li>Publicly available report </li></ul><ul><li>Restricted communication </li></ul>
  • 4. Expert Panel <ul><li>Selection principles </li></ul><ul><ul><li>Recognized scientific authorities </li></ul></ul><ul><ul><li>Disciplinary expertise </li></ul></ul><ul><ul><li>Un-biased – excluded: </li></ul></ul><ul><ul><ul><li>Dental community </li></ul></ul></ul><ul><ul><ul><li>Previously expressed opinion </li></ul></ul></ul><ul><li>Selected and appointed by LSRO </li></ul>
  • 5. Expert Panel <ul><li>Meryl Karol, PhD (Chair) </li></ul><ul><li>U of Pittsburgh </li></ul><ul><li>Stanley Berent, MS, PhD </li></ul><ul><ul><li>U of Michigan </li></ul></ul><ul><li>Robert Brent, MD, PhD </li></ul><ul><ul><li>Thomas Jefferson U </li></ul></ul><ul><li>James Bruckner, MS, PhD </li></ul><ul><ul><li>U of Georgia </li></ul></ul><ul><li>John Doull, MD, PhD </li></ul><ul><ul><li>U of Kansas Med School </li></ul></ul><ul><li>M. Eric Gershwin, MD </li></ul><ul><ul><li>U Cal School of Med </li></ul></ul><ul><li>Ronald Hood, MS, PhD </li></ul><ul><ul><li>U of Alabama </li></ul></ul><ul><li>Genevieve Matanoski, MD, DrPH </li></ul><ul><ul><li>Johns Hopkins U </li></ul></ul><ul><li>Raphael Rubin, MD </li></ul><ul><li>Thomas Jefferson U </li></ul><ul><li>Bernard Weiss, PhD (Consultant) </li></ul><ul><ul><li>U of Rochester </li></ul></ul>
  • 6. Panel Experience <ul><li>Past presidents of toxicology societies </li></ul><ul><li>Editors of major scientific journals </li></ul><ul><li>Department chairs </li></ul><ul><li>Endowed professorships </li></ul><ul><li>Authors of preeminent textbooks </li></ul><ul><li>Authors of thousands of publications </li></ul><ul><li>Members of advisory & NAS panels </li></ul><ul><li>Recipient of numerous awards </li></ul>
  • 7. Panel Expertise <ul><li>Toxicology (5) </li></ul><ul><li>Neuro/behavioral toxicol (2) </li></ul><ul><li>Pathology (1) </li></ul><ul><li>Allergy (1) </li></ul><ul><li>Immunology (2) </li></ul><ul><li>Pediatrics (1) </li></ul><ul><li>Developmental tox (3) </li></ul><ul><li>Reproductive tox (1) </li></ul><ul><li>Psychology (1) </li></ul><ul><li>Epidemiology (2) </li></ul><ul><li>Public health (2) </li></ul><ul><li>Environmental and occupational health (2) </li></ul><ul><li>Toxicokinetics (1) </li></ul><ul><li>Risk assessment (1) </li></ul>
  • 8. Panel Experience <ul><li>Past presidents of toxicology societies </li></ul><ul><li>Editors of major scientific journals </li></ul><ul><li>Department chairs </li></ul><ul><li>Endowed professorships </li></ul><ul><li>Authors of preeminent textbooks </li></ul><ul><li>Authors of thousands of publications </li></ul><ul><li>Members of government advisory & NAS panels </li></ul><ul><li>Recipient of numerous awards </li></ul>
  • 9. Restricted Communication <ul><li>Communicate with the Panel through LSRO </li></ul><ul><ul><li>Maintain transparency </li></ul></ul><ul><ul><li>Eliminate bias </li></ul></ul><ul><ul><li>Ensure the entire panel receives all input </li></ul></ul><ul><li>Panel reports any unofficial or ex parte communication </li></ul>
  • 10. Miscellany <ul><li>LSRO staff will write the report </li></ul><ul><li>Report will express Expert Panel consensus and will not attribute individual opinions </li></ul><ul><ul><li>Attempt to reach consensus wording </li></ul></ul><ul><ul><li>If necessary include minority opinions </li></ul></ul><ul><li>Post presentation slides on our web site </li></ul>

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