MINOT STATE UNIVERSITY
Immunology (Bio 465)
MWF 9-9:50 a.m.
Immunobiology (7th edition) by Janeway et al., published by Garland Science.
Chapters 1-10 covered in most detail. Parts of other chapters partially covered.
Supporting material from a variety of texts/sources. (The Immune System, Peter
Parham) **Take advantage of the supporting material on the CD and on the
Heidi Super, Ph.D.
Office: Moore 217
office hours: MWF 10:00-11:00 a.m. or ANY time agreed on by appointment.
Course web page:
An introductory course in immunology, focusing initially on basic cell biology and
molecular mechanisms related to the mammalian immune response. Later focus
will include the description of the normal immune response during infection and
in immunization and immune dysfunction related to allergy and disease.
Lab activities will include hands-on experiments as well as reading and
discussion of immunology-related research papers. Lab meets on Thursdays
11:00 a.m. to 1:50 p.m. in Moore 318 or in a designated classroom.
Attendance is mandatory. ( Lab will meet briefly, August 28th,
3-4 lecture-based exams will be administered as well as a comprehensive final.
Final exam is Tuesday, December 16th 2008, 8:-9:50 a.m. Students will also
be assessed on a written term paper or presentation on an immunology topic.
Laboratory activities will be included in assessment.
Point distribution (subject to minor modification)
4 exams 200-250 pts
Term Paper/presentation 50 pts
Lab ~80 pts
Final exam 100 pts
**Your grade is calculated using a straight percentage. In certain instances a
borderline percentage will be recognized and the student rewarded to reflect
marked improvement. All graded work will be returned so that the student can
track his/her own percentage. Your percentage is calculated by dividing your
points by total points! Total points will be posted periodically on the website.
Check the exam dates ASAP!I f you fail to take an exam at the designated
time (due to illness, official MSU event or other emergency/important conflict
only) I will allow you to make arrangements to take it within 3 school days.
However, I require you to contact me personally (confirmed email, phone call
or personal discussion) as soon as you know you will miss the exam. e.g.
Unless you are hospitalized, unconscious etc. you must notify me before the
scheduled exam. You will not be excused for non-emergency appointments
(dentist , haircut, work schedule etc).
Again, lab attendance is mandatory and subject to the guidelines as the
ATTENDANCE POLICY/TEACHING PHILOSOPHY
I do not track or award points for attendance to lecture. If you have a specific
reason for leaving early or often during a lecture, please inform me. Regular
attendance is simply expected. For most students academic success correlates
with regular attendance. Students are responsible for all information
disseminated at each lecture including changes to exam dates, assignments or
due dates. Points may be earned through assignments given in lecture, and
students must be present in lecture to earn those points.
Success in the course requires effort beyond attendance. While there are many
approaches to success, most students find following along in the text, re-writing
of notes and careful attention to figures used in class a useful guide for
enhancing lecture material. Course material will accumulate quickly and will build
on itself. Stay on top of lecture material. Read before coming to lecture.
My exams are designed to make you thinkers, not necessarily memorizers!
Take responsibility for your success in this course. Be seen and heard! If my
office hours are not convenient for you, please make regular appointments to ask
questions. In the past most genetics classes have naturally formed peer
discussion groups, with or without my input. Many times students teach it better
than I do! In any case, do not hesitate to seek help and do so as early as
possible in the semester.
Students requiring help with disabilities are encouraged to communicate your
needs with me and to utilize MSU’s disability services. Please call or visit
Evelyn Klimpel, Student Health and Development Center---South Entrance,
Cell phone policy
The classroom will be a cell phone-free zone, where students and instructors
deserve uninterrupted time. It is expected that no phones will ring or vibrate
audibly and no texting will occur during lecture OR lab hours in my class. If the
policy is repeatedly violated, a student will be asked to choose between the
phone in the classroom and credit for the course…Texting or cell phone use of
any kind during exams will result in a zero for the exam, no questions
asked, no second chances.
Course Schedule(subject to modification)
Week 1 (LAB WILL MEET THIS WEEK)
Aug 27, 29 Introductions/guidelines / introduction to immunology/CHPT. 1
Sept. 1 No class—Labor Day
Sept 3,5 Components of the immune system (overview/cells/tissues)
Innate immunity -- CHPT. 2
Sept. 8,10,12 Adaptive immunity---antigen recognition-- CHPT. 3
Week 4 (enrollment rosters to Registrar)
Sept 15,17,19 Generation of B and T cell receptors—CHPT. 4
Sept 22,24,26 Antigen Presentation to T-cells—CHPT 5
Sept. 29 Exam 1
Oct. 1, 3 Antigen Presentation to T-cells—CHPT 5
Oct. 6,8,10 Cell signaling (overviews) through B/T cell receptors
Oct 13,15,17 Development and survival of B/T cells---CHPT. 7
Week 9 (Midterm deficiencies reported)
Oct. 20,22,24 Putting all together----Immunity by T-cells---CHPT. 8
Oct 27 Exam 2
Oct 29, 31 Putting all together----Immunity by T-cells---CHPT. 8
Nov. 3,5,7 Putting all together----Humoral/antibody response---CHPT. 9
Nov. 10,12,14 Putting all together----Humoral/antibody response---CHPT. 9
Nov 17,19,21 The BIG picture---the immune response CHPT.10
Week 14 (No Lab this week—Thanksgiving!)
Nov 24 Exam 3
Nov. 26 The BIG picture---the immune response CHPT.10
Nov. 28 Thanksgiving break---no class
Dec. 1,3,5 Failures of immune response—CHPTs 11/12/13
Failures of immune response—CHPTs 11/12/13
Dec. 8, 10 Failures of immune response—CHPTs 11/12/13
Dec.,12 Exam 4
Dec 16 Final Exam (8:00-9:50 a.m.)