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  • 1. Professor Yi-Ming Arthur Chen Yi-Ming A. Chen M.D., M.S., Sc.D. Distinguished Professor, Institute of Microbiology and Immunology National Yang-Ming University (NYMU) Taiwan Email: arthur@ym.edu.tw Current Positions Director International Health Program, NYMU Dean Office of International Affairs, NYMU Director AIDS Prevention and Research Center, NYMU 1
  • 2. Joint appointment Professor Institute of Brain Research, NYMU Institute of Clinical Medicine, NYMU Research member Vaccine Research and Development Center National Health Research Institute Taiwan Committees services in the campus: Member: Biosafety Level 3 lab committee (2004 till mow) Member: Sonogram committee (2009-2011) Chairman: Ethical committee (2009-2011) Education 1975-82 M.D., Department of Medicine, National Yang-Ming Medical College, Taiwan 1982-84 M.S., Institute of Microbiology and Immunology, NYMU, Taiwan 1986-90 Sc.D., Department of Cancer Biology, Harvard School of Public Health, Boston, MA, USA 2
  • 3. Working experiences 1982-1984 Teaching Assistant, Department of Microbiology and Immunology, NYMU, Taiwan 1984-1986 Aviation Doctor, Air-force General Hospital, (Military services), Taiwan 1986 Lecturer, Department of Microbiology and Immunology, NYMU 1990-1992 Visiting Scientist, Lab of Molecular Oncology, National Cancer Institute, USA 1992-1998 Associate Professor, Institute of Public Health, NYMU, Taiwan 1992-1994 Associate Research Member, Institute of Biomedical Sciences, Academia Sinica, Taiwan 1998-2007 Professor, Institute of Public Health, NYMU, Taiwan 2002-2003 Visiting Scientist, HIV Drug Resistance Program, NCI, USA Advisory/steering committee and society 1992-2004 Member, AIDS Advisory Committee, Centers of Disease Control, Ministry of Health, Taiwan 3
  • 4. 2004-2009 Member, Committee for AIDS Prevention and HIV-infected People’s Rights Protection, Executive Yuan, Taiwan 1994-2008 Founder and Coordinator, Living with Hope Organization (希望工 作坊) 1993-2009 Board Member, Taiwan Society of Preventive Medicine (has been elected as secretary general in 1993-1996, as chairman in 1997-2003) 1996-2006 Advisory Board on Health Issues, Consumer Foundation, Taiwan (消基會,衛生保健組) 1996-2009 Board member, Taiwan AIDS Hope Association (台灣社團法人愛 之希望協會) 1998-2006 Council of Representative, Asia Pacific AIDS Services Organization 2001-2009 Member, AIDS Education Advisory Committee, Ministry of Health, Taiwan 2004-2009 Member, Steering committee, Therapeutic Research, Education and AIDS Training in Asia (TREAT Asia) (has been elected as the chair since 2008) 2001.2003Regional Task Force on HIV/AIDS Care and support in Asia 4
  • 5. 2002.2005 Vice Chairman, Global Chinese AIDS Network (全球華人抗愛滋 聯盟) 2008-2010 Vice Chairman, Global Chinese AIDS Network (全球華人抗愛滋 聯盟) 2001 Medical Advisory Board, OmniViral Therapeutics LLC 2005-2007 Chairman, Taiwan AIDS Quilt Association (台灣愛滋被單協會) 2006-2009 Board member, Harmony Home Association (台灣關愛之家協 會) 2003-2009 Board member, Taiwan Society of Epidemiology 2007-2010 Chairman, Taiwan Harm Reduction Association (台灣減害協會) 2006-2009 Consultant, Centers for Disease Control, Taiwan 2007-2009 Consultant, Anti-drug Usage association, Tao-Yuan Prefecture, Taiwan (桃園縣毒品危害防制委員會) 2007-2009 Consultant, Taipei City Government 2008-2009 Board Member, Taiwan Society of Microbiology 2008-2010 Managing Supervisor, Taiwan Society of Preventive Medicine 2008-2009 Board Member, Taiwan Can Love Association (台灣肯愛協會) 2008-2009 TREAT Asia Steering Committee Chair 5
  • 6. 2009 Committee Member, Global Vaccine Access Council (University of Western Ontario, Canada) Member of the following societies: International Liver Cancer Association (member #100708), American Association for Cancer Research (AACR) (member #52595), American Society of Microbiology and Immunology, American Society of Human Genetics, International AIDS Society (ID number 32042), Taiwan Society of Epidemiology, Taiwan Society of Preventive Medicine, Taiwan Society of Microbiology, Society of Public Health of ROC, Society of Cancer of ROC, Chinese Medical Association. Honors and awards 1. Scholarship from Society of Microbiology of ROC, Yen Shi-Chung Award, 1983. 2. Scholarship from the Ministry of Education to study abroad, Taiwan, R.O.C., 1986-89. 6
  • 7. 3. Scholarship from the Fogarty International Center, National Institutes of Health, Program of International Training Grants 1989-92. 4. Education and Culture Award, Significant Contribution to the Scientific Education for the Public, from the Ministry of Education, Taiwan, 1993. 5. Research award, from the National Science Council, Taiwan, 1993, 1994, 1995, 1997, 1999 and 2000. 6. Secretary General, the First, Second and Third Taipei International AIDS Conferences, 1990, 1992 and 1994. 7. Candidate for the International Prince Mahidol Award from Thailand, nominated by the Department of Health, Executive Yuan, R.O.C., 1994. 8. Young Investigator Award, First Joint Annual Conference of the Society of Oncology, Taiwan, 1996. 9. Who’s Who in the World, 2001, 18th edition. 10. Who’s Who in Medicine and Healthcare, 2002-2003. 11. Scholarships from the National Science of Council of ROC for short-term training (2003). 12.Outstanding Research Award from National Science Council, 2008. 13. Outstanding alumnus, Fu-Xin Primary school, 2004. 7
  • 8. 14. Invited as a reviewer for the following grant applications: National Science Council (committee members on the Public Health and Environmental Sciences), University Grants of Hong Kong, Specific Region of China and Pfizer AIDS foundation. 15. Best Paper Award from the Urbani Foundation 2005 and 2007. 16. Award to Special contribution to harm reduction program, 2007 from Ministry of Health. 17. The Second Best Research Paper Award of the Chinese Medical Association Annual meeting, 2007. 18. The Best Research Paper Award of the Taipei City Hospital grants, 2007. 19. Outstanding alumnus (Academic achievement), National Yang-Ming University, 2009. 20. Associate Editor, BMJ-Infectious Disease (since 2008); BMJ- Research Note (since 2008). 18. Editorial board member: Chinese Journal of Medicine, The Open Hepatology Journal (since 2008), Newsletter for Research on Applied Ethics (since 2000, in Chinese), Liver Cancer Review Letters (since 2009), World Journal Hepatology (2009-2013). 8
  • 9. 19. Ad hoc referee for the following journals, institutions and conference organizers: Hepatology, Lancet AIDS Research and Human Retroviruses, Blood Journal of Hepatology Journal of infectious Disease Experimental Biology and Medicine Taiwan J. Public Health Jouranl of Chinese Society of Physiology Acta Pharmacol Sin Infection Genetic and Evolution Retrovirology International Journal of Drug Policy Environmental Health Perspectives the XIII, XIV, XV and XVI International AIDS Conferences; 9
  • 10. th th the 6 and 7 International Conference on AIDS in Asia and Pacific (ICAAP); th the 4 IAS meeting National Medical Research Council of Singapore Hong Kong Department of Health Welcome Trust 10
  • 11. Publication List Referred papers: (*corresponding author) 1. Chen YM, Hu CP, Wong FH, et al. Circulating immune complexes in the sera and ascites of hepatocellular carcinoma patients. Chinese J. Micro. Immunol. 19:34-45, 1986. 2. Chen YM, Hu C, Chen P, et al. Nuclear antigens reacted with sera and ascites of hepatocellular carcinoma patients. Hepatology 8:547-552, 1988. 3. Matsuda Z, Chou MJ, Matsuda M, Huang JH, Chen YM, Redfield R, Mayer K, Essex M and Lee TH. Human immunodeficiency virus type 1 has an additional coding sequence in the central region of the genome. Proc. Natl. Acad. Sci., USA 85: 6968-6972, 1988. 4. Chen YM, Lee TH, Samuel KP, Okayama A, Tachibana N, Miyoshi I, Papas TS, and Essex M. Antibody reactivity to different regions of human T-cell leukemia virus type-I (HTLV-I) gp61 in infected people. J Virol 63: 4952-4957, 1989. 11
  • 12. 5. Chen YM, Lee TH, Wiktor SZ, Shaw GM, Murphy EL, Blattner WA and Essex M. Type-specific antigens for serological discrimination of HTLV-I and II infection. Lancet 336: 1153-1155, 1990. 6. Chen YM, Gomez-Lucia E, Okayama A, Tachibana N, Lee TH, Mueller N and Essex M. The antibody profile of early HTLV-I infection. Lancet 336: 1214-1216, 1990. 7. Okayama A, Chen YM, Tachibana N, Shioiri S, Lee TH, Tsuda K and Essex M. High incidence of antibodies to HTLV-I tax in blood relatives of adult T-cell leukemia patients. J. Infect. Dis. 163: 47-52, 1991. 8. Chen YM, Okayama A, Lee TH, Tachibana N, Mueller N and Essex M. Sexual transmission of HTLV-I associated with the presence of the anti- tax antibody. Proc. Natl. Acad. Sci. USA 88: 1182-1186, 1991. 9. Chen YM and Essex M. Identification of a recombinant HTLV-II envelope protein with distinguishing reactivities to sera from HTLV-II carriers. AIDS Res. Hum. Retroviruses 7: 453-457,1991. 10. Chen YM, Zhang X-q, Dahl C, Samuel KP, Schooley RT, Essex M and Papas TS. Delineation of type-specific regions on human T-cell leukemia virus envelope glycoproteins. J. Immunol. 147: 2368-2376, 1991. 12
  • 13. 11. Chen YM*. Serological discrimination of HTLV-I and HTLV-II infection by recombinant protein-western blot assays. Biomed. Pharmacotheraphy 45:274, 1991. 12. Okayama A, Kober B, Chen YM, Allan J, Lee TH, Shioiri S, Tachibana N, Tsuda K, Mueller N, Mclane MF, Maayan S, Markink R, Orgad S and Essex M. Unusual pattern of antibodies to HTLV-I in family members of adult T-cell leukemia patients. Blood 78: 3323-3329, 1991. 13. Samuel KP, Hodge DR, Chen YM and Papas TS. Nef protein of the human immunodeficiency viruses (HIV-1 and HIV-2) and simian immunodeficiency virus (SIV) are structurally similar to leucine zipper transcriptional activation factors. AIDS Res. Hum. Retroviruses 7: 697-706, 1991. 14. Zhang X-q, Yang L, Ho DD, Kuritzkes D, Chen I, Chen YM and Schooley RT. HTLV-I and HTLV-II Specific antibody dependent cellular cytotoxicity: strain specificity and epitope mapping. J. Infect. Dis. 165: 805-812, 1992. 15. Maayan S, Dan M, Marlink R and Chen YM*. Exposure to Human Retroviruses HTLV-I, HTLV-II and HIV among Israeli IV drug abusers. Int. J. Epidemio. 21:995-997, 1992. 13
  • 14. 16. Whang-Peng J, Chen YM, Knutsen T, Zhao W-P and Tsai S. Chromosome studies in HTLV-I, II, and HIV-1, 2 cell lines infected in vivo and in vitro. JAIDS J. Acqui. Immun. Defic. Syndr. 6: 930-940, 1993. 17. Chen YM*, Jang Y-J, Kanki PJ, Wang J-J, Montali RJ, Samuel KP and Papas TS. Isolation and characterization of simian T-cell leukemia virus type II from New World monkeys. J. Virol. 68: 1149-1157, 1994. 18. Hodge DR, Chen YM and Samuel KP. Oligomeraization of the HIV-2 Nef Protein: mutational analysis of the heptad leucine repeat motif and cysteine residues. AIDS Res. Hum. Retroviruses 11: 65-79, 1995. 19. Chen YM. Taiwan's sex-workers have less than 1% infection. AIDS Analysis Asia 1: 2 1995. 20. Chang L-J, Chen YM, Chen, M-Y, Chou C-C, Twu SJ, Huang L-M. HIV 10 years later-where do we stand now? J Biomed Sci 2: 1-11, 1995. 21. Yao C, Wang W-W, Chung Y-M, Su Y-L, Liu C-Y and Chen YM*. Transfusion-acquired AIDS in Taiwan. J. Formos. Med. Assoc. 95: 51-55, 1996. 22. Chen YM*, Lin H-C and Chou P. A population-based epidemiological study of human T-cell leukemia virus type I infection in Kin-Hu, Kinmen. Int. J. Cancer 59: 569-573, 1996. 14
  • 15. 23. Yao C, Kao S-S, and Chen YM*. Cost-benefit analyses of the HIV-1 and HIV-1/HIV-2 screening program in blood donation centers in Taiwan. Chin. J. Public Health (Taipei), 15: 483-496, 1996. 24. Chang P, Liau M-Y, Yang C-M, Ho M-S, Lee C-H, Chen YM and Horng C-B. Cost analysis of establishing the capability of producing MMR, DTaP, HBV, and OPV vaccines in Taiwan. Chin. J. Public Health (Taipei), 15: 517-524, 1996. 25. Chen YM*, Chang L-Y, Fu C-Y and Chou P. A survey of knowledge, attitudes and practices (KAP) concerning AIDS among female sex workers from massage parlors in Taiwan. Chin. J. Public Health (Taipei), 16: 439-454, 1997. 26. Shieh B, Lee C-M, Su I-J, Chen YM and Li C. Molecular subtyping of the V3 loop sequences detected in HIV-1-positive patients at the National Cheng Kung University Hospital. Chinese J. Micro. Immunol. 30: 46-54, 1997. 27. Li C, Yan Y-P, Shieh B, Lee C-M, Lin R-Y, and Chen YM*. Analysis of the CKR5 allele in AIDS patients and female sex workers in Taiwan. J. Formos. Med. Assoc. 96: 979-984, 1997. 15
  • 16. 28. Chen YM*, Chen S-H, Chen J-Y and Osame M. Antibody reactivities to tumor-suppressor protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I infected people with differing clinical status. Int. J. Cancer 71:196-202, 1997. 29. Chen Y-J, Shih L-S, Chang J-G, Whang-Peng J, and Chen YM*. Frequent detection of aberrant RNA transcripts of the CDKN2 gene in human gastric adenocarcinoma. Int. J. Cancer 71: 350-354, 1997. 30. Chen YM*, Yu PS, Lin C-C and Jen I. Surveys of HIV-1 HTLV-I and other sexually transmitted diseases among female sex workers in Taipei city and prefectures, Taiwan from 1993 to 1996. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 18: 299-303, 1998. 31. Chen YM*, Lee C-M, Lin R-Y, Chang H-J. Molecular epidemiology and Trends of HIV-1 Subtypes in Taiwan. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 19: 393-402, 1998. 32. Chen YM*, Shiu J-Y, Tzeng SJ, Li-Sun Shih, Yi-Jen Chen and Lui W-Y. Characterization of the glycine-N-methyltransferase-gene expression in human hepatocellular carcinoma. Int. J. Cancer 75: 787-793, 1998. 16
  • 17. 33. Chen Y-J, Shih L-S and Chen YM*. Quantitative analysis of CDKN2, p53 and retinoblastoma mRNA in human gastric carcinoma. Int J Oncol 13: 249-254, 1998. 34. Chen YM*, Lin R-H, Lee C-M, Fu C-Y, Chen S-C and Syu W-J. Decreasing levels of anti-Nef antibody correlate with increasing viral loads and AIDS disease progression. AIDS Res. Human Retroviruses 15: 43-50, 1999. 35. Chen YM*, Ting S-T, Lee C-M, W-T Liu, Pan W-H, TA Chang, Chou P. Community-based molecular epidemiology of human T-cell leukemia virus type I infection in Taiwan and Kinmen: Implication of the origin of the cosmopolitan subtype in North East Asia. AIDS Res Human Retroviruses 15: 229-237, 1999. 36. Liou YM, Chou P, Chen YM*. Genotypic Analysis of HCV infection in Kinmen. J. Microbiol. Immunol. Infect. 33: 63-68, 2000. 37. Chen YM*, Chen LY, Wong FH, Lee CM, Chang TJ, Yang-Feng TL. Genomic structure, expression and chromosomal localization of the human glycine N-methyltransferase gene. Genomics 66: 43-47, 2000. 38. Chen YM*, Huang KL, Jen I, Chen SC, Liu YC, Chuang YC, Wong JC, Tsai JJ. Temporal trends and molecular epidemiology of HIV-1 Subtypes 17
  • 18. in Taiwan from 1988 to 1998. JAIDS J. Acquir. Immun. Defic. Syndr. Hum. Retrovirol. 26: 274-282, 2001. 39. Chen YM*, Rey WY, Lan YC, Lai SF, Huang YC, Wu SI, Liu TT, Hsiao KJ. Antibody reactivity to HIV-1 Vpu in HIV-1/AIDS patients on highly active antiretroviral therapy. J. Biomed. Sci. 10: 266-275, 2003. 40. Yang MH, Chen YM, Kuo BI, Wang KY. Quality of life and related factors for people living with HIV/AIDS in Northern Taiwan. J. Nurs. Res. 11: 217-26, 2003. 41. Liu HH, Chen KH, Shih YP, Lui WY, Wong FH, Chen YM*. Characterization of reduced expression of glycine N-methyltransferase in the cancerous hepatic tissues using two newly developed monoclonal antibodies. J. Biomed. Sci. 10: 87-97, 2003. 42. Tseng TL, Shih YP, Huang YC, Wang CK, Chen PH, Chang JG, Yeh KT, Chen YM*, Buetow K. Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer. Cancer Res. 63: 647-654, 2003. 43. Chen SY, Lin JR, Darbha R, Liu TY, Lin CH, Chen YM*. Glycine N- Methyltransferase tumor susceptibility gene in the Benzo(a)pyrene- detoxification pathway. Cancer Res. 64: 3617-3623, 2004. 18
  • 19. 44. Lan YC, Liu HF, Shih YP, Yang JY, Chen HY, Chen YM*. Phylogenetic analysis and sequence comparisons of structural and non-structural SARS coronavirus proteins in Taiwan. Infect. Genetic. Evolu. 5: 261-269, 2005. 45. Lan YC, Liu TT, Yang JY, Chen YJ, Lu JJ, Chan YJ, Liu HF, Chen HY, Suing CA, Hsiao KJ, Ho MS, Chen YM*. Molecular epidemiology of SARS coronavirus infection in Taiwan. J. Infect. Dis. 191: 1478-1489, 2005. 46. Huang CY, Sun CT, Hsieh JL, Chen YM, Lin H. A novel small-world model: using social mirror identities for epidemic simulations. Simulation 81: 671-699, 2005. 47. Zhou J, Kumarasamy N, Zhang F, Zhao H, Han N, Li P, Lee MP, Chen YM, Wong WW, Wang DCC, Anand S, Cecelia JA, Pujari S, Joshi K, Lee CKC, Kaur S, Kamarulzaman A, Ditangco R, Capistrano R, Paton NI, Yap M, Phanuphak P, Siangphe U, Khongphattanayothing M, Vibhagool A, Kiertiburanakul S, Kiatatchasai W, Chuah J, Fankhauser W, Dickson B, Frost K, Wong S, Cooper DA, Law MG, Petoumenos K. Predicting short-term disease progression among HIV-infected patients in Asia and 19
  • 20. the Pacific region: Preliminary results from the TREAT Asia HIV Observational Database (TAHOD) HIV Med 6: 216-223, 2005. 48. Chen WJ, Yang JY, Lin JH, Fann CSJ, Osyetrov V, King CC. Chen YM, H. L. Chang HL, Kuo HW, F. Liao F, Ho MS. Nasopharyngeal shedding of severe acute respiratory syndrome-associated coronavirus is associated with genetic polymorphisms. Clin. Infect. Dis. 42: 1561-1569, 2006. 49. Chen, YM*, Liang SY, Chu DC, Lee YM, Chang L, Jung SY, Chen HY, Chjan YJ, Ho MS, Liang KY, Jang Y-J, Chu T-C. Epidemiological and genetic correlates of SARS coronavirus infection in a hospital with the highest nosocomial infection rate in Taiwan in 2003. J. Clinc. Microbio. 44: 359-365, 2006. 50. Hsieh YH, Lee SM, Chen CW-S, Chen YM, Wu S-I, Lai SF. Estimating the HIV-1-infected population size within hard-to-count MSM groups: the case of gay saunas patrons in Taipei area. Physica A 362: 495-503, 2006. 51. Chen YM*, Lan YC, Lai SF, Yang JY, Tsai SF, Kuo HS. HIV-1 CRF07_BC infections, injecting drug users, Taiwan. Emerg. Infect. Dis. 12: 703-705, 2006. 20
  • 21. 52. Lee CM, Chen SY, Lee YCG, Huang CYF, Chen YM*. Benzo[a]pyrene and glycine N-methyltransferse interactions: Gene expression profiles of the liver detoxification pathway. Toxicol. Appl. Pharmacol. 214: 126-135, 2006. 53. Chiu HC, Wang FD, Chen YM, Wang CT. Effects of human immunodeficiency virus type 1 transframe protein p6* mutations on viral protease-mediated Gag processing. J. Gen. Virol. 87: 2041-2046, 2006. 54. Qiu JT, Chang TC, Lin CT, Chen YM, Li F, Soong YK, Lai CH. Novel codon-optimized GM-CSF gene as an adjuvant to enhance the immunity of a DNA vaccine against HIV-1 Gag. Vaccine Vaccine. 2006 Aug 4; [Epub ahead of print]. 55. Shih YP, Chen CY, Liu SJ, Chen KH, Lee YM, Chao YC, Chen YM.* Identification of the Epitopes Responsible for Neutralizing Antibody and DC-SIGN Binding on the Spike Glycoprotein of the Severe Acute Respiratory Syndrome Coronavirus. J. Virol. 80: 10315-10324, 2006. 56. Hsu CH, Hwang KC, Chao CL, Chang SGN, Ker CC, Chien LC, Ho MS, Lin JG, Chen YM, Chou P. The lesson of supplementary treatment with Chinese medicine on severe laboratory-confirmed SARS patients. Am. J. Chin. Med. 34: 6927-6935, 2006. 21
  • 22. 57. Zhou J, Paton NI, Ditangco R, Chen YM, A Kamarulzaman, N Kumarasamy, CKC Lee, PCK Li, TP Merati, P Phanuphak, S Pujari, A Vibhagool, F Zhang, J Chuah, KR Frost, DA Cooper and MG Law. Experience with the use of a first-line regimen of stavudine, lamivudine and nevirapine in patients in the TREAT Asia HIV Observational Database. HIV Med. 8: 8-16, 2007. 58. Coulibaly S, Yen PMN, Fu LA, Chen YM*. Needs assessment of people living with HIV/AIDS in Taiwan. Taiwan J. Public Health 26: 38-48, 2007. 59. Huang YC, Lee CM, Shih YP, Chung MY, Chang YH, Huang JSW, Ho MTD, Pan CC, Wu TL, Hsu JM, Yang S, Lin MW, Chen YM.* Characterization of the haplotypes, loss of heterozygosity and expression levels of glycine N-methyltransferase gene in prostate cancer. Clin. Cancer Res. 13: 1412-1420, 2007. 60. Chen YM* and Kuo HS. HIV-1 in Taiwan. Lancet 369: 623-625, 2007. (has been chosen as the Article of the Month, April 2007 by the International Harm Reduction Association). 61. Lin YT, Lan YC, Chen YJ, Liu TT, Yang JY, Wong WW, Wang CT, Chen YM.* Molecular epidemiology and full-length genomic analysis of HIV-1 22
  • 23. circulating recombinant form 07_BC strains from injecting drug users in Taiwan. J. Infect. Dis. 195: 1283-1293, 2007. 62. Huang YC, Chung MY, Chang YH, Huang JSW, Wu TL, Hsu JM, Yang S, Lin MW, Chen YM.* The CYP19 tri-nucleotide Del/Del genotype is a susceptibility marker for prostate cancer in a Chinese population. Urology 69: 996-1000, 2007. 63. Lien SP, Shih YP, Lien S, Tsai JP, Leng CH, Chen HW, Lin MH, Liu SY, Chen YM, Chong P, Liu SJ. Identification of synthetic vaccine candidates against SARS CoV infection. Biochem. Biophys. Res. Commun. 358: 716-721, 2007. 64. Chen CY, Ping YH, Lee HC, Chen KH, Lee YM, Lian DC, Jap TS, Lin CH, Kao LS, Chen YM.* ORF8a of the severe acute respiratory syndrome coronavirus not only promotes viral replication but also induces apoptosis. J Inf Dis, 2007; 196: 405-415. 65. Zhou J, Dore GJ, Zhang F, Lim PL, Chen YM*. Hepatitis B and C virus coinfection in the TREAT Asia HIV Observational Database. J Gastroent Hepatol, 2007; 22: 1510-1518. 66. Medah I, Lai SF, Chuang SY, Chang CL, Yen PMN, Chen YM*. Knowledge, attitude, and practices towards human immunodeficiency 23
  • 24. virus type 1 infection among new entrant university students in Taiwan. Taiwan J Public Health 2007; 26: 324-337. 67. Liu SP, Li YS, Chen YJ, Chiang EP, Li AFY, Lee YH, Tsai TF, Hsiao M, Huang CF, Chen YM.* Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in liver. Hepatology 2007; 46: 1413-1425. 68. Goka EAC, Yen PMN, Chiou JQ, Lin CL, Wu CM, Fan HH, Chen YM*. Knowledge attitudes and practice of antenatal mothers on HIV/AIDS and their satisfaction with PMTCT program in Taiwan. Int. J. Coop. 2007; 2: 65-88. 69. Lan YC, Elbeik T, Dileanis J, Ng V, Chen YJ, Leu HS, Cheng SH, Wong JC, Wong WW, Chen YM*. Molecular epidemiology of HIV-1 subtypes and drug resistant strains in Taiwan. J. Med. Virol. 2008; 80: 183-191. 70. Huang YC, Chen M, Li AFY, Su CH, Shyr YM, Ho DMT, Chen YM*. Glycine N-methyltransferase is a favorable marker for human cholangiocarcinoma. J. Gastroenterol. Hepatol. 2008; 23:1384-9. Epub 2008 Jul 8. 71. Wang SF, Huang JC, Lee YM, Liu SJ, Chan YJ, Chau YP, Chuang P, Chen YM*. DC-SIGN mediates avian H5N1 influenza virus infection in 24
  • 25. cis and in trans. Biochem. Biophys. Res. Commun. 2008 373: 561-6. Epub 2008 Jun 30. 72. Chuang PC, Liu H, Sola C, Chen YM, Jou R. Spoligotypes of mycobacterium tuberculosis isolates of a high tuberculosis burden aboriginal township in Taiwan. Infect. Genet. Evol. 2008; 8: 553-557. 73. Liao, YJ, Liu SP, Lee CM, Yen CH, Chuang PC, Chen CY; Tsai TF; Huang SF, Lee-Wu Yan-Hwa, Chen YM*. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma. Int. J. Cancer, 2009; 124: 816-826. (epublication Sep 2008). 74. Yen CH, Hung JH, Liu SP, Chen SY, Chou TY, Tsai TF, Darbha R, Hsieh LL, Chen YM*. Glycine N-Methyltransferase Interacts with Aflatoxin B1 and Blocks its Carcinogenic Effect. Toxicol. Appl. Pharmacol. 2009; 235: 296-304 (epublication December 2008). 75. Wang SF, Chen KH, Thitithanyanont A, Yao L, Lee YM, Chan YJ, Liu SJ, Chong P, Liu WT, Huang JC, Chen YM.* Generating and Characterizing Monoclonal and Polyclonal Antibodies against Avian H5N1 Hemagglutinin Protein. Biochem. Biophys. Res. Commun. 2009; 15: 382: 691-696. 25
  • 26. 76. Lee CM, Shih YP, Chen YM*. Characterization of the 5' Regulatory Region of the Human Glycine N-methyltransferase Gene. Gene, 2009 15; 443: 151-157. 77. Chen M, Huang YC, Ko IL, Yang S, Chang YH, Huang W J-S, Yi-Ming Arthur Chen YM*. The rs1447295 at 8q24 is a risk variant for prostate cancer in Taiwanese men. Urology 2009 May 8. [Epub ahead of print] 78. Wang SF, Huang JC, Lee YM, Liu SJ, Chan YJ, Chau YP, Chuang P, Chen YM*. Influenza A virus in Taiwan, 1980-2006: Phylogenetic and antigenic characteristics of the hemagglutinin gene. J. Med. Virol. 2009; 81: 1457-1470. 79. Zhou J, Elliott J, Li PCK, Lim PL, Kiertiburanakul S, Kumarasamy N, Merati TP, PUjari S, Chen YM, Phanuphak P, Vonthanak S, Sirisanthana T, Sungkanuparph S, Lee CKC, Kamarulzaman A, Oka S, Zhang F, Tau G Ditangco R. Risk and prognostic significance of tuberculosis in patients from The TREAT Asia HIV Observational Database. BMC Infect Dis 2009; 9: 46-55. 80. Srasuebkul P, Lim PL, Lee MP, Kumarasamy N , Zhou J, Saphonn V, Zhang FJ, Li PCK, Pujari S, Merati TP, Oka S, Choi JY, Lee C KC, Kamarulzaman A, Tau G, Ditangco R, Chen YM, Phanuphak P, 26
  • 27. Sungkanuparph S, Sirianthana T, Smith J and Law M G. Short-term clinical disease progression in HIV-1-positive patients taking combination antiretroviral therapy: TAHOD results. Clin. Inf. Dis. 2009; 48: 940-950. 81. Tsai MC, Chen YM, H Cheng. Enhanced Expression of Glycine N- Methyltransferase by Adenovirus-Mediated Gene Transfer in Mixed Neuronal Culture is Neuroprotective. Annals of the New York Academy of Sciences. In press. 82. Land S, Cunningham P, Frost K, Katzenstein D, Kantor R, Chen YM, Oka S, DeLong A, Sayer D, Smith J, Dax EM, Law M. The TREAT Asia quality assessment scheme to standardize the outcome of HIV genotypic resistance testing in a group of Asian laboratories. J. Virol. Meths. 2009, in press. 83. Chen YM*, Liao YJ, Liu SP, Tsai TF. Phenotypic difference of two GNMT-/- mouse model for hepatocellular carcinoma. Hepatology, 2009, in press. 84. Lee YM, Wang SF, Chan YJ, Chen YM*. 2006-2007 Outbreak of reassortant influenza B virus in north Taiwan. BMJ Res Note, 2009; 2: 85-96. 27
  • 28. 85. Chen YM*, Yen CH, Liu SP, Liao YJ. Response to the letter to the editor from Dr. Conrad Wagner. Toxicol. Appl. Pharmacol. 2009, in press. 86. Lee YM, Lin HJ, Lee CM, Chen YJ, Chen YM* Molecular Epidemiology of HCV Genotypes among Injection Drug Users in Taiwan: Full-length sequences of two new subtype 6w strains and a recombinant form_2b6w. J Med Virol, 2009, In press. 87. Oyomopito R, Lee MP, Phanuphak P, Lim PL, Citangco R, Zhou J, Sirianthana T, Chen YM, Pujar S, Kumarasamy N, Sungkanuparph S, Lee CKC, Kumarulzaman A, Oka S, Zhang FJ, Mean CV, Merati TP, Tau G, Li PCK. Measures of country and site resourcing predict virologic suppression, immunologic response and HIV disease progression following HAART in the TREAT Asia HIV Observational Database (TAHOD). Submitted, 2009. 88. Liu SP, Li YS, Lee CM, Yen CH, Huang SF, Chien CH, Chen YM*. Susceptibility to aflatoxin B1-related hepatocellular carcinoma in glycine N-Methyltransferase knockout mice. Toxicol Appl Pharmacol, in revision. 89. Zhou J Pujari S , Srasuebkul P, Sungkanuparph S, Lim PL, Kumarasamy N, Chuah J, Kumar RN, Chen YM, Oka S, Choi JY, Lee MP, Phanuphak P, Kamarulzaman A, Lee C, Fujie Z, Ditangco R, Saphonn V, 28
  • 29. Sirisanthana T, Parwati T, Merati, Smith J, Law MG. Deferred modification of antiretroviral regimen following documented treatment failure in Asia: results from The TREAT Asia HIV Observational Database (TAHOD) HIV Medicine, 2009, submitted. 90. Chiang SC, Chu FY, Cheng SH, Chen YM, Chen CK. Psychiatric comorbidity and prevalence of HIV and hepatitis C virus among illicit drug abusers in Taiwan: a cross-sectional study. BMC Res Note, submitted, 2009 91. Chuang PC, Chen HY, Chen YM, Jou R. Single nucleotide polymorphisms of cell wall biosynthesis associated genes and a phylogeny of principal genetic group 1 Mycobacterium tuberculosis complex. J Bacte, submitted, 2009. 92. Cheng SH, Peng ETC, Yeh CY, Morisky DE, Lan YC, Chen YM, Lyu SY. A Case-Control Study of HIV Infection among Incarcerated Female Drug Users: Impact of Sharing Needles and Having Drug-Using Sexual Partners. BMC Infec Dis, submitted, 2009. 93. Tsai TI, Chen IJ, Morisky D, Chen YM*. Service modalities and attitudes as keys in needle exchange programmes-a survey of service providers. Submitted, Int J Drug Policy, 2009. 29
  • 30. 94. Chen YJ, Huang YH, Kao DYT, Lan YC, Yang JY, Chen YM*. Risk factors associated with HIV-1 circulating recombinant form 07_BC infection among injection drug users in Taiwan. Submitted. AIDS. 2009. 95. Chang YJ, Chen HC, Lee BH, You SL, Lin CY, Pan MH, Chou YC, Hsieh CY, Chen YM, Cheng YJ, Chen CJ. Intratypic Variants of Human Papillomavirus Types 16, 18, 52 and 58 in Taiwan. Submitted, 2009. 96. Huang JC, Chang YF, Chen KH, Lee CW, Su LC, Chen CC, Chen YM*, Chou C*. Detection of Severe Acute Respiratory Syndrome (SARS) Coronavirus Nucleocapsid Protein in Human Serum using a Localized Surface Plasmon Coupled Fluorescence Fiber-optic Biosensor. Biosensors and Bioelectronics, submitted, 2009. 97. Pujari S , Srasuebkul P, Sungkanuparph S, Lim PL, Kumarasamy N, Chuah J, Kumar RN, Chen YM, Oka S, Choi JY, Lee MP, Phanuphak P, Kamarulzaman A, Lee C, Fujie Z, Ditangco R, Saphonn V, Sirisanthana T, Parwati T, Merati, Smith J, Law MG. Patient characteristics and treatment outcome associated with Protease Inhibitor (PI) use in the Asia-Pacific region. J Antimicrobiol Chemother, submitted, 2009. 30
  • 31. 98. Yen CH, Lu YC, Lee CM, Chen CY, Huang CH, Kao FJ, Chou TY, Wu Lee YH, Chen YM*. DEPDC6 is a GNMT-binding protein frequently overexpressed in hepatocellular carcinoma and associated with tumorigenesis. JEM, Submitted, 2009. 99. Kuo HCC, Fan APC, Kao DYT, Morisky DE, Chen YM*. Quality of Life and Needs Assessment on People Living with HIV and AIDS in Malawi. AIDS. 2009, submitted. 100. Chen YJ, Huang YH, Kao DYT, Lan YC, Yang JY, Chen YM*. Risk factors Associated with HIV-1 Circulating Recombinant Form 07_BC Infection among Injection Drug Users in Taiwan. JAIDS. Submitted. 101. Lee CM, Huang YZ, Chang TY, Chen YM*. The Androgen Response Element of Glycine N-Methyltransferase Gene is Located in the first Intron. Gene. In preparation, 2009. 102. Liao CF, Wang SF, Lin YT, Chen YM*. Identification of the DC-SIGN- interactive domains on the envelop glycoprotein of HIV-1 CRF07_BC. Retrovirol, 2009 In preparation. 103. Lin YT, Huang SW, Oka S, Kuritzkes DR, Hu Z, Giguel F, Liao CF, Chen YM*. Biological characterization and drug susceptibilities of CRF07_BC strains from treatment-naïve patients in Taiwan. In preparation, 2009. 31
  • 32. Patents 1. United States Patent: Detection and Correction of Abnormalities of Cells having Decreased Levels of Glycine N-methyltransferase. Patent number: 5994093 (Duration: Nov. 30, 1999-Nov. 30, 2019). 2. ROC Patent: Detection and Correction of Abnormalities of Cells having Decreased Levels of Glycine N-methyltransferase. Patent number: 086114505 (Duration: Oct. 4, 1997-Oct. 4, 2017). 3. United States Patent: Glycine N-methyltransferase monoclonal antibodies and methods of use therefore. Patent number: 7176291 (Duration: February 13, 2007-2027). 4. Establishment of a mouse liver tumor model and its application. Under review. (Patent application in five regions including US, Europe, mainland China, Taiwan and Japan) 5. A mouse model for depression, schizophrenia and Alzheimer’s disease. Under review ((Patent application in five regions including US, Europe, mainland China, Taiwan and Japan). 32
  • 33. Book Chapters 1. Jeng KS, Hu CP, Lo SJ, Chen YM, Su TS, Ting LP, Chou C H, Hana SH, Salfeld J, Pfaff E, Schaller H, Chang C. Production of hepatitis B virus by transfection of cloned hepatitis B virus DNA in a hepatoma cell line. In: Viral Hepatitis and Liver Disease. Alan R. Liss, Inc., 1988, pp. 355-359. 2. Chen YM, Essex M. Antibody responses to different regions of HTLV-1 gp61 in asymptomatic carriers, ATL patients and individuals with TSP. In: Human Retrovirology: HTLV (W. Blattner, Ed.). Raven Press, 1990, pp. 447-460. 3. Chen YM, Essex M. Immunogenicity of human retrovirus-specific proteins. In: Gene Regulation and AIDS (T. S. Papas, Ed.). Gulf Publishing Co., Houston, 1990, pp. 239-245. 4. Chen YM, Sankale J-L. Chapter 4: Other human retroviruses. In Essex, M., Mboup, S., Kanki, P. J. and Kalengayi, M. R. (eds.): AIDS in Africa. Raven Press, New York, 1994, pp. 67-95. 33
  • 34. 5. Horng C-B, Chen YM, Chang PL. Vaccine development in Taiwan. Proceedings of the Asia-Pacific Conference on Health Care in the 21st Century. Taipei, Taiwan. 1994. 6. Chen YJ, Lee MD, Liu MH, Chen PH, Chen YM. The study of p16 (MTS1) gene expression in gastric cancer cell lines and uncultured gastric cancers. In Nishi M, Sugano H, and Takahashi T, (eds): Proceedings of the 1st International Gastric Cancer Congress, Monduzzi Editore, Italy, pp. 713-717, 1995 7. Chen YM. Preventive Medicine. (Writer and Editor). Chinese Society of Preventive Medicine Press, 1996. 8. Chen YM, Lin R-H, Fu C-Y, Lin R-Y, Syu W-J. Decreasing levels of anti- Nef antibody correlate with increasing viral loads in HIV-1 infected people with differing clinical status. Proceedings of the 12th World AIDS Conference. Monduzzi Editore, Italy, volumn 2, pp. 627-634, 1998. 9. Chen YM, Lee C-M. Molecular epidemiology of HIV-1 in Taiwan: heterosexual males with HIV-1 E had significantly higher rate of transmission than those with HIV-1 B. Proceedings of the 12th World AIDS Conference. Monduzzi Editore, Italy, volumn 3, pp. 29-35, 1998. 34
  • 35. 10. Chen YM. HIV/AIDS in Taiwan. In AIDS in Asia, Lu YC and Essex M (ed.), p.p. 135-144, Kluwer Academic Publisher. 2004. 11. Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of genetic polymorphism of glycine N-methyltransferase gene in hepatocellular carcinoma. In Hormonal Carcinogenesis IV, Li JJ, Li SA and Llombart-Bosch A (ed.), p.p. 293-299, 2004. 12. Hsieh JL, Huang CY, Sun CT and Chen YM. Using the CAMIM Small- World Epidemic Model to Analyze Public Health Policies. In Proceedings of Western Multiconference, New Orleans, LA, pp. 63-69, 2005. 13. Sumodhee C., Hsieh J.L., Sun C.T., Huang C.Y., and Chen Y.M. Impact of Social Behaviors on HIV Epidemic: A Computer Simulation View. In Proceedings of IEEE Computational Intelligence for Modelling Control and Automation (CIMCA’05), Vienna, Austria, pp. 130-134. (IEEE), 2005. 14. Chen YM. The 2003 SARS outbreaks in Taiwan. Growing infections in Asia. Lu YC, Essex M and Robert B (eds.), Springer, pp. 119-134, 2008. 15. Wang SF and Chen YM. Chapter 5, The Interactions between Avian H5N1 Influenza Virus and Dendritic Cell-Specific ICAM-3 Grabbing Non- 35
  • 36. Integrin (DC-SIGN). Global View at Fight against Influenza.(Nova Science Publishers), In press, 2009. 16. Wang SF and Chen YM. The Emergence of HIV-1 Circulating Recombinant Form 07_BC Strains in Taiwan. Emerging Infectious Diseases: Global Trends, Surveillance and Eradication. (Nova Science Publishers). In press, 2009. Chinese articles: 1. [愛滋世界]。陳宜民。翻譯自 Jonathann Mann AIDS in the World. 2nd edtion. 1999. (全書共 632 頁)。預防醫學出版社出版。 2. [預防醫學]。陳宜民。巨流出版社。 3. [愛之新生]。陳宜民主編。第六版。2008. 4. [第三章:愛滋病病毒之分子流行病學] 。藍郁青,陳宜民。[愛滋病學]第二 版,。pp. 24-34, 2006. 5. [第二十六章:愛滋病疫苗研發現況及未來展望]。林郁婷,陳宜民。[愛滋病 學]第二版。pp. 332-344, 2006. 6. [諾貝爾生醫獎─人類乳突病毒與愛滋病病毒]。陳宜民。[科學月刊]。2008, 12 36
  • 37. 月號。468 期,924-931 頁。 Television or DVD Interviews CDC, 愛在擁抱, 2008 國科會,認識病毒, 2008 Asian Harm Reduction Association, 台灣愛滋減害成效報導 (在 2009 International Harm Reduction Conference 播出) 公共電視 有話好說 新型流感病毒專輯 2009-4-27 公共電視 有話好說 新型流感病毒專輯 2009-4-29 公共電視 有話好說 新型流感病毒專輯 2009-4-30 民視 新聞最前線 2009-5-2 37
  • 38. Conference Abstracts 1. Chen YM, Lee TH, Samuel KP et al. Antibody response to different regions of HTLV-1 gp61 in asymptomatic carriers. ATL patients and individuals with TSP. The Second International HTLV Meeting, Trinidad. Feb. 1989. 2. Chen YM, Lee TH, Samuel KP et al. Antibody reactivity to different regions of HTLV-1 gp61 in infected people. RNA tumor virus meeting. Cold Spring Harbor, USA. May 1989. 3. Chen YM, Lee TH, Samuel KP et al. Antibody reactivity to different regions of HTLV-1 gp61 in infected people Annual meeting of American Society of Microbiology, West Ontario, Canada. Sep. 1989. 4. Chen YM, Okayama A, Lee TH et al. Antibody reactivity of different high-risk groups to HTLV-1 ENV and Tax recombinant protein. Annual Meeting of Lab of Tumor Immunology, NIH, MD, USA. Sep. 1989. 5. Chen YM, Okayama A, Lee TH et al. Sexual transmission of HTLV-1 associated with the presence of the anti-Tax antibody. The Third International HTLV meeting, Hawaii. April 1990. 38
  • 39. 6. Chen YM, Gomez-Lucia, E., Okayama, A. et al. The antiobdy profile of early HTLV-1 infection. The Third International HTLV meeting, Hawaii. April 1990. 7. Chen YM, Lee TH, Wiktor SZ et al. Mapping the type-specific epitopes on the HTLV-1 and -II envelope glycoprotein. RNA tumor virus meeting. Cold Spring Harbor, USA. May 1990. 8. Gomez-Lucia E, Chen YM, Yu Q-C, Essex M. Experimental infeciton of monocytes by HTLV. RNA tumor virus meeting. Cold Spring Harbor, USA. May 1990. 9. Chen YM, Lee TH, Essex M. HTLV-1 Envelope glycoprotein:the biological and epidemiological significance. International Human Retro virology: HIV & HTLV Conference, Taipei, R.O.C. Sep. 1990. 10. Chen YM, Wiktor SZ, Shaw GM. et al. Type-specific antigens for serological discrimination of HTLV-I and HTLV-II infection. The fourth International HTLV meeting. Jamaica, Feb. 1991. 11. Chen YM, Samuel KP, Blattner W et al. Mapping the type-specific regions on HTLV-I and HTLV-II envelope glycoprotein. International AIDS Conference. Florance Italy, June 1991. 12. Chen YM, Zhang X-g, Dahl C. et al. Delineation of type-specific regions 39
  • 40. on HTLV envelope glycoproteins and its serological application. The Sixth International AIDS in Africa Conference. Dakar, Senegal. Dec. 1991. 13. Chen YM. Delineation of type-specific regions on HTLV envelope glycoproteins by Recombinant protein-Western blot assay and ADCC. The NIH HTLV vaccine-perspective workshop. Bethesda, USA. Jan. 1992. 14. Chen YM. Delineation of the HTLV type-specific regions by recombinant Env proteins and ADCC assays. The Second International Taipei AIDS Conference. Taipei, ROC. May. 15. Chen YM, Kanki PJ, Jang YJ, et al. Isolation of simian T-lymphotropic virus type II (STLV-II) from new world monkeys. The IXth International Conference of AIDS, Berlin. 1993. 16. Jen I, Lan JF, Lin HT, Chen YM. A modified aids risk reduction model (ARRM) for female sex workers in Taiwan. The IXth International Conference of AIDS, Berlin, 1993. 17. Chen YM, Kanki PJ, Jang YJ, et al. Isolation of simian T-lymphotropic virus type II (STLV-II) from new world monkeys. Retroviruses meeting. Cold Spring Harbor, USA. May 1993. 40
  • 41. 18. Lee MS, Chen YM, Chen SH, King CC, Wu YC, Horng CB, Chou P. Evaluation of two hepatitis B virus immunization programs in an isolated islet-Kinmen, Fukien, Republic of China, 1993. The third International Conference on Viral Disease, Kunming, China, 1993. 19. Chen YM, Sheu T-T, Lee CM, Jang Y-J. The V3 region of HIV-1 isolates prevalent in Taiwan contains a unique signature and E subtype sequence. The Xth International Conference on AIDS, Yokohama, Japan, August 1994. 20. Jen I, Chen YM. The seropositive rates of HIV-1, HTLV-I, syphilis, and HBV infections among illegal sex workers and servants in Taipei city. The Third Taipei International AIDS Conference. Taiwan, ROC. August 1994. 21. Chin W-Y, Chang L-Y, Chou P, Chen YM. An evaluation of the impact of an AIDS education program offered to beauty parlor personnel in the Song-San District of Taipei, Taiwan. The Third Taipei International AIDS Conference, Taiwan, ROC. August 1994. 22. Yao C, Kuo H-S, Chen YM. Economic analyses of the blood screening programs for HIV-1 and HIV-2 in the blood donation centers in Taiwan. The Third Taipei International AIDS Conference. Taiwan, ROC. August 41
  • 42. 1994. 23. Chen YM, Lin H-C, Whang-Peng J. Molecular epidemiology of human immunodeficiency virus infection in Taiwan. First APSN International Symposium and Workshop, Singapore, August 1994. 24. Chen YJ, Jang YJ, Lee MD, Liu MH, Chen PH, Whang-Peng J, Chen YM. A novel mitochondrial ADP/ATP translocase gene identified from human gastric carcinoma tissue by mRNA differential display. The World Congress of Gastroenterology. Los Angeles, CA, USA, October 1994. 25. Chen YM, Lin H-C, Whang-Peng J. Molecular epidemiology and phylogenetic tree analysis of HIV-1 infection in Taiwan. 7th Asian-Pacific Congress of Clinical Biochemistry, Bangkok, Thailand, September 1995. 26. Chen YJ, Lee MD, Liu MH, Chen PH, Chen YM. The study of p16 (MTS1) gene expression in gastric cancer cell lines and uncultured gastric cancers. The Society of Surgical Oncology's 48th Annual Cancer Symposium, Boston, USA. March 1995. 27. Chen YM. Differential diagnosis of HIV-1 vs. HIV-2, HTLV-I vs. HTLV-II and HIV-1 subtyping. International Symposium on Diagnosis of Viral and Chlamydial Infection. Tainan, ROC. March 1996. 28. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to 42
  • 43. tumor suppressor protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I infected people with different clinical status. Retroviruses meeting, Cold Spring Harbor, USA. May 1996. 29. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I infected people with different clinical status. Annual meeting for Chinese Society of Oncology, Taipei, Taiwan. May 1996. 30. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I infected people with different clinical status. The XIth International Conference on AIDS, Vancuver, Canada. August 1996. 31. Chen YM. Current situation of HIV-1 infection in Taiwan, a community report. Global response to HIV/AIDS from Chinese communities. An official satellite symposium of the XIth International Conference on AIDS, Vancouver, Canada, August 1996. 32. Chen YM, Chen S-H, Fu C-Y, Chen J-Y, and Osame M. Antibody reactivities to p53 and HTLV-I regulatory proteins- tax, rex and tof in HTLV-I infected people. The 4th International AIDS Conference, Taipei, 43
  • 44. Taiwan. December 1996. 33. Yao C, Wang W-W, Chung Y-M, Su Y-L, Liu C-Y, and Chen YM. Transfusion-acquired AIDS In Taiwan. The 4th International AIDS Conference, Taipei, Taiwan. December 1996. 34. Chen YM, Ting S-T, Liu W-T, Pan W-H, Chou P. Community-based molecular epidemiology of human T-cell leukemia virus type I infection in Kin-hu, Kinmen and three townships in Taiwan. The 4th International AIDS Conference, Taipei, ROC. December 1996. 35. Jen I, Chang L-Y, Lin R-Y, Chen YM. Survey of knowledge, attitudes and practices concerning AIDS among female sex workers in Taipei, Taiwan. The 4th International AIDS Conference, Taipei, ROC. December 1996. 36. Chen YM, Lin C-C, Lin R-Y. Surveys of HIV-1, HTLV-I and other sexually transmitted infections (STI) among female sex workers in Taipei, Taiwan. The 4th International AIDS Conference, Taipei, ROC. December 1996. 37. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I infected people with different clinical status. 44
  • 45. Retroviruses meeting, Cold Spring Harbor, USA. May 1996. 38. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I infected people with different clinical status. Annual meeting for Chinese Society of Oncology, Taipei, Taiwan. May 1996. 39. Shiu J-YA, Tzeng S-J, Chen Y-J, Lui W-Y, Chen YM. cDNA cloning and sequencing of human glycine N-methyl transferase whose expression is diminished in human hepatocellular carcinoma. Annual meeting of Chinese Society of Oncology, Taiepi, Taiwan. May 1996. (*The first award of the poster competition). 40. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor protein p53 and HTLV-I regulatory gene products (Tof, Rev and Tax) in HTLV-I infected people with different clinical status. The XIth International Conference on AIDS, Vancuver, Canada. August 1996. 41. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I infected people with differing clinical status. VIII International Conference on Human Retrovirology: HTLV. Rio de Janeiro, Brazil. June 1997. 45
  • 46. 42. Chen YM, Ting S-T, Lee C-M, Pan W-H, Saitou N, Chou P. Population- based molecular epidemiology of human T-cell leukemia virus type I in Taiwan and Kinmen islands. VIII International Conference on Human Retrovirology: HTLV. Rio de Janeiro, Brazil. June 1997. 43. Yu PS, Jen I, Lin C-C, Lin R-Y, Chen YM. Surveys of HIV-1 HTLV-I and other sexually transmitted diseases among female sex workers in Taipei city and prefectures, Taiwan from 1993 to 1996. 4th International Congress of the AIDS in the Asia and Pacific. Manila, Philippine. Oct. 1997. 44. Chen YM. Current situation of HIV-1 infection in Taiwan, a community report. Global response to HIV/AIDS from Chinese communities. 4th International Congress of the AIDS in the Asia and Pacific. Manila, Philippine. Oct. 1997. 45. Chen YM, Shiu J-Y, Tzeng SJ, Lui W-Y. Characterization of glycine N- methyltransferase gene expression in human hepatocellular carcinoma. Regulation of Liver Gene Expression in Health & Disease. Cold Spring Harbor Laboratory, New York, USA. April 1997. 46. Chen Y-J, Shih L-S, Chang J-G, Whang-Peng J, Chen YM. Frequent detection of aberrant RNA transcripts of the CDKN2 gene in human 46
  • 47. gastric adenocarcinoma. The 2nd Annual Taiwan Joint Cancer Conference. Taiepi, ROC. May 1997. 47. Chen YM, Chen S-H, Osame M, Chen J-Y. Antibody reactivities to tumor suppressor protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I infected people with differing clinical status. VIII International Conference on Human Retrovirology: HTLV. Rio de Janeiro, Brazil. June 1997. 48. Chen YM. Comparison of a modified HIV-1 Monitor test and a branched DNA assay for the quantitation of HIV-1 RNA in triple therapy. 1998 Bangkok Symposium on HIV Medicine, Bangkok, Thailand. January 1998. 49. Chen YM. Comparison of a modified HIV-1 Monitor test and a branched DNA assay for the quantitation of HIV-1 RNA in triple therapy. 1998 Taipei Symposium on Current Treatment and Vaccine Development for HIV Infection. Taipei, ROC. April 1998. 50. Chen YM, Lin R-H, Fu C-Y, Lin R-Y, Syu W-J. Decreasing levels of anti-Nef antibody correlate with increasing viral loads in HIV-1 infected people with differing clinical status. The 12th World AIDS Conference. Geneva. June 1998. 51. Chen YM, Lee C-M, Lin R-Y. Molecular Epidemiology of HIV-1 in 47
  • 48. Taiwan: Heterosexual Males with HIV-1 E Had Significantly Higher Rate of Transmission than Those with HIV-1 B. The 12th World AIDS Conference. Geneva. June 1998. 52. Chen YM. The strategies of advocating AIDS prevention and treatment in Taiwan. Global response to HIV/AIDS from Chinese communities. An official satellite symposium of the 12th World AIDS Conference. Geneva. June 1998. 53. Chen YM and Lee C-M. Molecular epidemiology of HIV-1 infection in Taiwan. Annual Spring Meeting of the Taiwan Medical Assocation. May 1998. 54. Chen YM. The present situation of HIV epidemics and treatment in Taiwan. International Conference on the Treatment of AIDS, Beijing, Oct. 1998 55. Chen YM. Decreasing levels of anti-Nef antibody correlate with increasing HIV-1 viral loads and AIDS disease progression. The 7th Annual Meeting of Chinese Society of Immunology, Taipei, Nov. 1998. 56. Lee C-M, Lin R-H, Syu W-J, Chen S-C, Chen YM. A Study of the Anti- Nef Antibody as a Serological Marker for AIDS Disease Progression. The 30th Annual Meeting of Chinese Society of Microbiology, Taipei, Nov. 48
  • 49. 1998. 57. Hsu Y, Chen Y-J, Chen S-T, Chen YM. Characterization of Rb and CDKN2 (p16INK4A/MTS1) tumore suppressor genes in human esophageal carcinoma. The 3rd Taiwan Joint Cancer Conference. Taipei, April 1998. (*Among 59 posters participated in the competition, it has won the top 8 award).Lin J-R V, Lee C-M, Hsieh 58. L-L, Liu T-Y, Chen YM. The Interaction of Glycine N-methyltransferase and Carcinogens- (Benzo[a]pyrene and Aflatoxin B1) in Liver Cancer Cells. The 30th Annual Meeting of Chinese Society of Microbiology, Taipei, Nov. 1998. 59. Chen YM. Current situation of HIV infection and prevention strategy in gay community in Taiwan. (Invited speaker) UNAIDS and ASAP Workshop on MSM. Singapore, Feb. 1999. 60. Chen YM, Lee C-M, Lin R-H, Syu W-J, Chen S-C. Antibody Responses to HIV-1 Nef and Gag Proteins Correlate with Viral Loads and AIDS Disease Progression. 5th International AIDS Conference in Taipei. Feb. 1999. 61. Chen YM, Lee C-M, Lin R-Y, Chen S-C. Molecular Epidemiology and Trends of HIV Subtypes in Taiwan. 5th International AIDS Conference in 49
  • 50. Taipei. Feb. 1999. 62. Chen YM, Lin R-H, Lee C-M, and Syu W-J. Evaluation of the anti- HIV-1-Gag and Nef Antibody Reactivities as Clinical Markers for AIDS Disease Progression and Response to Triple Therapy. (Invited speaker). 3rd International Symposium on Clinical Virology, Tai-Nan, Taiwan, march 1999. 63. Chen YM, Huang K-L, Chen S-C, Chang H-J. Molecular epidemiology of HIV-1 Infection in Taiwan. Fifth International Congress on AIDS in Asia and Pacific. Kuala Lumpur. (Oral) Oct. 1999. 64. Chen YM. The present situation of human right issues of HIV/AIDS patients in Taiwan. (Invited speaker). Fifth International Congress on AIDS in Asia and Pacific. Kuala Lumpur. Oct. 1999. 65. Chen YM, Lin J-R V, Lee C-M, Lin C-H, Hsieh L-L, Yang S-C, Liu T-Y, Wong F-H. The Interaction of Glycine N-methyltransferase and Carcinogens- (Benzo[a]pyrene and Aflatoxin B1) in Liver Cancer Cells. Annual Meeting of Chinese Society of Oncology, Taipei, April 1999. 66. Chen YM, Lee C-M, Lin J-R V, Chen L-Y, Lin C-H, Hsieh L-L, Yang S- C, Liu T-Y, Wong F-H. Glycine-N-methyltransferase-gene expression and the hepatocarcinogenesis. (Invited speaker) 2nd International 50
  • 51. Symposium on liver Cirrhosis and Liver Cancer. Kyoto, Japan, June 1999. 67. Chen YM. Molecular epidemiology of HIV-1 and HTLV-I in Taiwan. Invited speaker at the Branch of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA, Feb. 2000. 68. Chen YM. Decreasing levels of anti-Nef antibody correlate with increasing viral loads and AIDS disease progression. Invited speaker at the Symposium on Recent Advancement of HIV Therapy. Taipei, Feb. 2000. 69. Chen YM. Molecular epidemiology and Trends of HIV-1 infection in Taiwan. Invited speaker at the Year 2000 Taipei Symposium on the Clinical Management and Laboratory Diagnosis of AIDS. Taiepi, April 2000. 70. Chen YM. Anti-Tat antibody and subtype E have synergistic effect on the sexual transmission of HIV-1. XIII International AIDS Conference. (Oral) Durban, South Africa, July 2000. 71. Chen YM. The AIDS Epidemics and the Human Right Issues in Taiwan. Invited speaker at the Satellite Symposium on “HIV/AIDS in Chinese Community-Threats and Opportunities in the New Millennium” XIII 51
  • 52. International AIDS Conference. July 2000. 72. Chen YM. Virologic markers associated with AIDS disease progression. Invited speaker at the National Annual AIDS Meeting of Philippine. Manila, Oct. 2000. 73. Chen YM. Molecular Epidemiology of HIV-1 Subtypes: Methodology and Application. Invited speaker at the National Annual AIDS Meeting of Philippine. Manila, Oct. 2000. 74. Chen YM. GNMT and liver cancer. Invited speaker at the Laboratory of Population Genetics, National Cancer Institute, NIH, Bethesda, Feb., 2000. 75. Chen YM, Chen LY, Lin JR, Liu TY, Yang-Feng TL. Genomic Structure, Chromosomal Localization and Functional Study of the Human Glycine th N-methyltransferase Gene. The 50 Annual Meeting of American Society of Human Genetics. Philadelphia, USA, Oct. 2000. 76. Tseng TL, Chen YM, Struewing JP, Buetow K. Identification and characterization of novel polymorphisms/mutation in the glycine N- th methyltransferase gene in liver cancer. The 50 Annual Meeting of American Society of Human Genetics. Oct. Philadelphia, USA, 2000. 77. Chen YM. Functional study and characterization of novel 52
  • 53. polymorphisms of GNMT gene in liver cancer patients. In the “Recent advanced diagnosis and treatment in HCC meeting” held by the Chinese Society of Clinical Oncology, Dec. 2000. 78. Chen YM, Chung CL, Jen I, Lan YC, Wu SI, Hsu H. Molecular Epidemiology and temporal trends of HIV-1 subtypes in Taiwan and a survey on the HIV-1, syphilis and sexual behavior among men attending gay saunas in Taipei City. International AIDS Conference in Taiwan. (Invited speaker) March 2001. 79. Chen YM, Chung CL, Wu SI, Hsu H. A Survey on the HIV-1, syphilis and sexual Behavior Among Men Attending Gay Saunas in Taipei City. 2001 Hong Kong AIDS Meeting. August 2001. 80. Chen YM, Chung CL, Wu SI, Hsu H. An HIV and STD Prevention Program for Men Attending Gay Saunas in Taipei City. 2001 Hong Kong AIDS Meeting. August 2001. 81. Chen YM, Chung CL, Jen I, Lan YC, Wu SI, Hsu H. Surveys on the HIV-1, syphilis and sexual behavior among men attending gay saunas in th Taipei City. The 6 ICAAP in Melbourne, Australia, Oct. 2001. 82. Chen YM, Lei WY, Huang YC, Wu SI. The seroconversion of anti-Vpu antibody is associated with the recovery of humeral immunity in patients 53
  • 54. th on highly active antiretroviral therapy. The 6 ICAAP in Melbourne, Australia, Oct. 2001. 83. Chen YM. Molecular epidemiology of HIV-1 and surveys of STDs in gay th saunas in Taiwan. (invited seminar) The 15 Annual Meeting of Japanese AIDS Society, Nov 2001. 84. Chen YM. Clinical Implications of anti-Nef and anti-Vpu antibodies in th patients on HAART. (invited seminar) The 15 Annual Meeting of Japanese AIDS Society, Nov 2001. 85. Tseng TL, Chen YM, Shih YP, Buetow KH. Genotypic and phenotypic characterization of a putative tumor suppressor gene, GNMT, in liver st cancer. The 51 Annual Meeting of American Society of Human Genetics. San Diego, USA, Oct 2001. 86. Chen YM, Lee CM, Shih YP, Tseng TL, Buetow K. Delineation of mechanism of glycine N-methyltransferase gene control in liver cancer. st The 51 Annual Meeting of American Society of Human Genetics. San Diego, USA, Oct 2001. 87. Chen YM. Delineation of the mechanism of glycine N-methyltransferase th gene control in hepatocellular carcinoma. The 4 France-Taiwan Conference on Virus and Cancer. Kenting, Taiwan, Nov. 2001. 54
  • 55. 88. Shih YP, Huang YC, Tseng TL, Chen YM. A Study of the Glycine N- methyltransferase Genotypic and Phenotypic Characterization in Human Heptoma Cell Lines. The 35th Annual Meeting of Chinese Society of Microbiology, Taipei, Dec. 2001. 89. Chen SY, Wong FH, Liu TY, Chen YM. A Study of the Interaction between 4S-PAH-binding Protein (GNMT) and Benzo[a]pyrene. The 35th Annual Meeting of Chinese Society of Microbiology, Taipei, Dec. 2001. 90. Lee CM, Chen YM. A Study of the Mechanism of the Human GNMT Gene Control in Hepatocellular Carcinoma. The 35th Annual Meeting of Chinese Society of Microbiology, Taipei, Dec. 2001. 91. Elbeik E, Lan YC, Dileanis JA, Marlowe N, Ng V, Chen YM. Prevalence of HIV-1 genotypic mutations in the protease and reverse transcriptase genes from infected individuals in Taiwan: Treatment challenges. The XIV International AIDS Conference, Barcelona, Spain, July, 2002. 92. Jen I, Chen YM. Advocating a new health policy for mandatory condom distribution and nationwide behavior surveillance system establishment in Taiwan. The XIV International AIDS Conference, Barcelona, Spain, July, 2002. 93. Hung CP, Wang WC, Jen I, Chen YM. Two-year consecutive survey of 55
  • 56. the prevalence rates of HIV and syphilis infection among men who have sex with men attending saunas in Taipei. The XIV International AIDS Conference, Barcelona, Spain, July, 2002. 94. Chen YM, Elbeik E, Lan YC. Molecular epidemiology of HIV-1 subtypes and drug-resistant strains in Taiwan. The Third Annual HDR meeting. Virginia, 2002. 95. Chen YM. SARS Prevention in Taiwan. International Conference on SARS Control. Beijing. April 2003. 96. Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of Genetic Polymorphism of Glycine N-Methyltransferase Gene in Hepatocellular Carcinoma. 4th volume of Hormonal Carcinogenesis. The 4th International Symposium on Hormonal Carcinogenesis, Spain, Jun. 2003. 97. Chen YM. Molecular epidemiology of HIV-1 subtypes and SARS coronavirus infection in Taiwan. UCLA School of Public Health. Invited seminar. August 11, 2003. 98. Chen YM, Liang CY, Shih YP, et al. Establishment of a confirmatory test for SARS infection. International Conference on SARS. Beijing. August 2003. 56
  • 57. 99. Chen YM. The establishment and operation of the PWA’s Rights’ Advocacy Association in Taiwan. International Seminars on HIV/AIDS: Social Behavior, Stigma and Discrimination. Beijing, China, July 2004. 100. Lan YC, Elbeik T, Lai SF, Chen KT, Leu HS, Cheng S H, Wong W W, Wong J C, Chen YM. Molecular Epidemiology of HIV-1 Subtypes and Drug Resistant Strains in Taiwan: The resurgence of HIV-1 subtype B in Taiwan during 1999 to 2000 survey. The XV International AIDS Conference, Bangkok Thailand, July 2004. 101. Lin YT, Hsieh SL, Chen YJ, Lai SF, Chen YM. The serum level of the decoy receptor 3 (DcR3) is associated with HIV-1 subtype and AIDS disease progression. (oral presentation) The XV International AIDS Conference, Bangkok Thailand, July 2004. 102. Lai SF, Hong CP, Lan YC, Chen KT, Wong WW, Hu BS, Chen YM. Molecular epidemiology of HIV-1 in men who have sex with men from gay saunas in Taiwan from 2000 to 2003. The XV International AIDS Conference, Bangkok Thailand, July 2004. 103. Chen YM, Lan YC, Yang JY et al., Molecular epidemiology of SARS coronavirus infections in Taiwan. 2004 International Symposium on the Prevention and Control of SARS and Avian Flu. Beijing, China, August 57
  • 58. 22 to 24, 2004. 104. Chen YM. Molecular epidemiology of HIV-1 and SARS infections in th Taiwan. (Keynote speech) The 6 Guangdong, Hong Kong, Macau and Taiwan Conference on Preventive Medicine. Macau, Oct. 30, 2004. 105. Lin YT, Hsieh SL, Chen YJ, Lai SF, Chen YM. The serum level of the decoy receptor 3 (DcR3) is associated with HIV-1 subtype and AIDS th disease progression. The 6 Guangdong, Hong Kong, Macau and Taiwan Conference on Preventive Medicine. Macau, Oct. 30, 2004. 106. Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of genetic polymorphism of Glycine N-Methyltransferase gene in prostate th cancer. The 6 Guangdong, Hong Kong, Macau and Taiwan Conference on Preventive Medicine. Macau, Oct. 30, 2004. 107. Huang YC, Shih YP, Li CC, Liao LY, Chen YM. Characterization of genetic polymorphism of Glycine N-Methyltransferase gene in prostate th cancer. The 54 Annual Meeting of American Society of Human Genetics. Toronto, Canada, Oct. 2004. 108. Hsieh JL, Huang CY, Sun CT, Chen YM. Using the CAMIM small-world epidemic model to analyze public health policies. Western Multiconference 2005. 58
  • 59. 109. Tsai TT Tsai, Chuang PH, Lin IF, Chen YM, Wu WH, Chang HJ, Chuang JH. Using Claims Data for Establishing a Syndromic Surveillance System in Taipei City. In International Association for Computer Information Systems Conference. 2005. 110. Chen SY, Lee CM, Liu HH, Darbha R, Hsieh LL and Chen YM. Glycine N-methyltransferase is a novel cytosolic receptor for aflatoxin B1 and it can prevent AFB1-DNA adducts formation. The Twentieth National Biomedical Combined Conference. Taipei, Taiwan, March 26-27, 2005. 111. Huang YC, Chung MY, Chang YH, Huang JSW, Ho MTD, Pan CC Wu TL, Chen YM. Genetic polymorphism and expression of glycine N- methyltransferase (GNMT) gene in prostate cancer. The Twentieth National Biomedical Combined Conference. Taipei, Taiwan, March 26-27, 2005. 112. Chen YM. Molecular epidemiology and serological diagnosis of SARS infection in Taiwan. Invited speaker at the Tartu University, Tartu, Estonia, April 6, 2005. 113. Chen YM. Evolving HIV epidemic in Taiwan: context, current situation and response. Invited speaker at the Estonia National Medical days. Tallinnas, Estonia, April 7-8, 2005. 59
  • 60. 114. Sumodhee C., Hsieh J.L., Sun C.T., Huang C.Y., and Chen YM. Impact of Social Behaviors on HIV Epidemic: A Computer Simulation View. In Proceedings of IEEE Computational Intelligence for Modelling Control and Automation (CIMCA’2005), Vienna, Austria. 115. Medah Isaie, Lai SF, Chang YU, Li CC, Kang HF, and Chen YM. Knowledge, attitude, and practices towards HIV/AIDS among first-year university students in Taiwan-A National Survey. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 116. Chen YM, Lai SF, Lan YC, Chen KH, Chen YJ. Molecular epidemiology of HIV-1 infection among injecting drug users in Taiwan-Report of an emergent situation. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 117. Wang CC, Wong WW, Chen YM. The effect of HAART on the disease progression of HIV/AIDS patients co-infected with HBV or HCV. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 118. LinYT, Chen YJ, Lai SF, Hsieh SL, Chen YM. Serum decoy receptor 3 (DcR3) level is associated with HIV-1 subtype B and slower AIDS disease progression. 7th International Congress on AIDS in Asia and the 60
  • 61. Pacific, Kobe, Japan, July. 2005. 119. Tsui JJ , Lai SF, Chen YM, Wong WW, Yang SY. A Study of the Holistic Care Model for HIV/AIDS patients. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 120. Chang YR, Medah Isaie, Lai SF, Kang FH, and Chen YM. Advocacy for establishment of a guideline for the management of Students Living with HIV/AIDS at schools in Taiwan. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 121. Chang JL, Chen YM, Ko NY. Help PLWHAs Being Familiar to Medical Care Systems: The HAART Partnership of Living with Hope Organization in Taiwan. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 122. Lee YM, Lai SF, Chen KD, Wong WW, Chen YM. Molecular Epidemiology of Hepatitis C Virus Subtypes in HIV/AIDS Patients in Taiwan. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 123. Lai SF, Lan YC, Lin YH, Chen KT, Wong WW, Chen YM. Molecular epidemiology of HIV-1 infection in men who have sex with men (MSM) from gay saunas in Taiwan from 2003 to 2004. 7th International 61
  • 62. Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 124. Lan YC, Elbeik Tarek, Lai SF, Chen KD, Leu HS, Cheng SH, Wong WW, Wong JC, Chen YM. Molecular Epidemiology of HIV-1 Subtypes and Prevalence of HIV-1 Genotypic Drug Resistant Strains in Taiwan. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 125. Hsu SC, Lin SR, Haung HC, Wang CC, Chen YM. Display of AIDS memorial quilts and at-risk babies crib quilts to advocate MTCT program in Taiwan. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 126. Chang CJ, Wang CC, Chen YM. Use CD4 Counts, HBV and HCV Tests to Enhance the Participation and Effects of AIDS Education among PLWHAs in Prisons. 7th International Congress on AIDS in Asia and the Pacific, Kobe, Japan, July. 2005. 127. Chen YM. Molecular epidemiology of HIV-1 infection among injecting drug users in Taiwan. 2005 Taipei International Conference on Drug Control and Addition Treatment. Taipei, Taiwan, November 22-24, 2005. 128. Lee CM, Chen SY, Huang CYF, Lee YCG, Chen YM. Benzo[a]pyrene and Glycine N-Methyltransferse Interactions: Gene Expression Profiles 62
  • 63. of the Liver Detoxification Pathway. The 9th Asian-Pacific Conference on Transcription, ACT-IX. December. December 15-17, 2005. 129. Chen YM. Establishment of a transgenic mouse model to study the th interaction between GNMT and aflatoxin B1. 5 NHRI Conference on Viral Hepatitis and Hepatocellular Carcinoma. Chu-nan, Taiwan. March 24-25, 2006. 130. Chen YM. HIV-1 drug resistance surveillance of treatment naïve persons in a clinical network. Antiretroviral Resistance Prevention, Surveillance and Monitoring in Asia World Health Organization, Global AIDS Program – Vietnam and Asia Regional Global AIDS Program. Hanoi, Vietnam March 27-31, 2006. 131. Chen YM. Molecular epidemiology, phylogenetic and genomic analysis of HIV-1 circulating recombinant form 07_BC among injecting drug users in Taiwan. First Taiwan-Netherlands Workshop on Pathogenomics. Amsterdam, Netherlands, April 9-11, 2006. 132. Chen YM. Trade Related Infections, Traveling and the Spread of Emerging Infectious Diseases. 2006 International Workshop on “WTO Agreement and Public Health”. May 3-4. Taipei, Taiwan. 133. Hsieh JL, Huang CY, Sun CT, Chen YM, Chu D. Using the Agent- 63
  • 64. based Epidemic Simulation CAMIM to Assess Public Health Policies. 2006 Mexican International Conference on Artificial Intelligence. Mexico. 134. Lan YC, Lin YT, Chen JJ, Liu TT, Chen YM. Phylogenetic and genomic analyses of six full-length CRF07_BC variants isolated from injecting drug users in Taiwan. XVI International AIDS Conference, Toronto, Canada. (abstract No. CDA0118) 135. Jang YR, Jiang YH, Chuang SY, Zhou J, Lan YC, Wong WW, Chen YM. Taiwan HIV observational database: baseline and retrospective data. XVI International AIDS Conference, Toronto, Canada. (abstract No. CDC0013) 136. Chen YJ, Huang YH, Lan SF, Chen YM. Phylogenetic analysis of Taiwanese HIV-1 CRF08_BC strains: tracing the origin and dissemination of this CRF in Taiwan. XVI International AIDS Conference, Toronto, Canada. (abstract No. CDC0365) 137. Hung KC, Chen YM. AIDS education combined with a display of AIDS memorial quilts to raise awareness among teenagers in Taiwan. XVI International AIDS Conference, Toronto, Canada. (abstract No. CDC1565). 138. Zhou J, Dore G, Chen YM, Law M. Hepatitis B and C virus coinfection 64
  • 65. among patients with HIV in Asia HIV observational database. XVI International AIDS Conference, Toronto, Canada. (abstract No. TUAB0302, oral presentation) 139. Chang KC, Chang CC, Mai CK, Jung KC, Chen YM. Development and implementation of a harm reduction and AIDS education program in the detention centers and prisons in Taiwan. XVI International AIDS Conference, Toronto, Canada. (abstract No. THPE0732, poster presentation). 140. Chen YM, Huang YH, Chen CJ, Lai SF, Yang JY, Kuo HS. Molecular epidemiology of HIV-1 in Taiwan: emergence of CRF07_BC among injecting drug users in Taiwan. XVI International AIDS Conference, Toronto, Canada. (abstract No. MOPE0359. poster presenation) 141. Chen YM. Molecular epidemiology of HIV-1 Subtypes and Circulating Recombinant Forms in Taiwan. Taiwan-Japan Conference on Infectious Disease Control, Taipei, 2006. 142. Chen YM. Molecular epidemiology of HIV-1 Subtypes in Taiwan. 8th International Taipei AIDS conference. Taipei, 2006. 143. Chen YM. Molecular epidemiology of HIV-1 Subtypes in Taiwan. Taiwan Medical Week. Invited speaker. Taipei, Nov. 13, 2006. 65
  • 66. 144. Liu SP and Chen YM. Characterization of a GNMT gene knockout th mouse model. 8 Meeting of Liver Cancer Study Group of Taiwan. Kaohsiung, Taiwan, Dec. 9, 2006. 145. Tsai TI, Chen YM, Yang SY, Huang YF, Kuo HS. Evaluating preliminary th harm reduction programs in Taiwan. 18 International Conference on the HR. Warsaw, Poland, May13-17 2007. 146. Chen YM, Lin YT, Lan YC, Chen YJ, Huang YH, Lee CM, Liu TT, Wang CT. Molecular epidemiology of HIV-1 infection and full-length genomic analysis of circulating recombinant form 07_BC strains from injecting drug users in Taiwan. Conference on HIV Pathogenesis, Treatment and Prevention. 4th IAS Conference on HIV Pathogenesis and Treatment, Sydney, Australia, 22-25 July 2007. (Poster) 147. Jang YR, Zhou J, Chung SY, Wong WW, Chen YM. Prognostic markers related to AIDS diagnoses and deaths among HIV-1/AIDS patients in Taiwan. Conference on HIV Pathogenesis, Treatment and Prevention. 4th IAS Conference on HIV Pathogenesis and Treatment, Sydney, Australia, 22-25 July 2007. (Poster) 148. Chang KC, Chang ZX, Huang CK, Chen JW and Chen YM. Development and implement of an outreach and Peer education 66
  • 67. program in NSP station in Taiwan. 8th International Congress on AIDS in Asia and the Pacific, Sri Lanka, August 19-23, 2007. 149. Chen YM, Lin YT, Lan YC, Chen YJ, Huang YH, Lee CM, Liu TT, Wang CT. Molecular epidemiology of HIV-1 infection and full-length genomic analysis of circulating recombinant form 07_BC strains from injecting drug users in Taiwan. 8th International Congress on AIDS in Asia and the Pacific, Sri Lanka, 2007. (oral presentation). 150. Chen YM. Molecular epidemiology of HIV-1 and HCV infections in Taiwan. International Conference on AIDS and TB. Taipei, 2007. (Invited speaker). 151. Liu SP, Li YS, Chen YJ, Chiang EP, Li FY, Lee YH, Tsai TF, Hsiao M, Chen YM. Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in liver. The 57th ASHG, San Diego, California. Oct. 23, 2007. 152. Chen YM. Aim for Excellence: The experiences of international collaboration at Yang-Ming University. UK-Taiwan Higher Education Conference, Taipei, Taiwan. November 5, 2007. (Invited speaker). 153. Chen YM. Molecular epidemiology of HIV-1 and HCV infection in Taiwan. 2007 Annual Meeting of Taiwan Society of Biochemistry and 67
  • 68. Molecular Biology. Oct. 19-20, 2007. (Invited speaker). 154. Chen YM. Molecular epidemiology of HIV-1 and HCV infection in Taiwan. International Conference on Control of Tropical Infectious Diseases and Cancer in Taiwan and South Pacific. Nov. 10-11, 2007. (Invited speaker). 155. Chen YM. Review the history: epidemiology of SARS coronavirus infection in Taiwan. 2007 International Symposium on Humanity Care in the Post-SARS Era. Nov. 21-22, 2007. (Invited speaker). 156. Chen YM. Serological and genetic correlates of SARS coronavirus infection. 2007 International Symposium on Humanity Care in the Post- SARS Era. Nov. 21-22, 2007. (Invited speaker). 157. Chen YM. HIV-1 infection and harm reduction program in Taiwan. 21st Japanese Society for AIDS Research Annual Meeting, Hiroshima, Nov30, 2007. (Invited speaker). 158. Chen YM. Molecular epidemiology of HIV and HCV infection in Taiwan. st 1 UK-Taiwan International Networking for Young Scientists Symposium on Infection and Immunity. (invited speaker) Taipei, March, 2008. 159. Chen YM. Characterization of a GNMT-/- mouse model for hepatocellular carcinoma. Joint Symposium between National Yang- 68
  • 69. Ming University , Taiwan and University of California San Diego. (invited speaker), San Diego, April 2008. 160. Chen YM. Searching for kinases and phosphatases associated with interaction between GNMT and DEPDC6 using RNAi screen. Taiwan – Broad Institute Joint Mini-symposium on RNAi Screen. (invited speaker), Taipei, May, 2008. 161. Lan YC, Lu CL, KH, Chen YM. Impact of a Harm Reduction Program on the Prevention of HIV-1 Infection among Injecting Drug Users in th Taiwan. (poster) 19 International Harm Reduction Association Conference, Spain, May, 2008. 162. Chen YM. Proteomic and epigenomic analyses of a GNMT-/- mouse model. Taiwan Proteomics Society Eastern International Conference, Tzu Chi Medical Center, (invited speaker), June, 2008. 163. Lan YC and Chen YM. Evaluation of the harm reduction program in Taiwan. XVII International AIDS Conference, Mexico Coty, 3-8 August 2008 (oral presentation). 164. Liao YJ and Chen YM. Glycine N-methyltransferase is associated with gender disparity in liver cancer susceptibility. 2008 Meeting on Mechanisms & Models of Cancer. Cold Spring Harbor Laboratory, NY, 69
  • 70. August 13-17, 2008. (Poster) 165. Lee YM, Lee CM and Chen YM. Molecular epidemiology of HIV and HCV infection among injection drug users in Taiwan. XVII International AIDS Conference, Mexico Coty, 3-8 August 2008 (Poster). 166. YR Chang, WW Wang and Chen YM. Clinical epidemiology of HIV-1 infection in Taiwan. XVII International AIDS Conference, Mexico Coty, 3-8 August 2008 (Poster). 167.Chen YM. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma. International Symposium in Regeneration Medicine. August 22, 2008, Taipei, Taiwan (invited speaker). 168. Chen YM, YJ Liao, SP Liu, TF Tsai. Glycine N-methyltransferase is nd associated with gender disparity in liver cancer susceptibility. 2 International Liver Cancer Association Annual Conference. Chicago, September 5-7, 2008 (Poster). 169. Chen YM. How we promote human right protection issues for HIV-1/AIDS patients in Taiwan. Presentation in Observatory of HIV and sexuality, in the Facultés Universitaires Saint Louis, au Salon des Professeurs, rue du Marais 109, 5ème étage, Belgium, 2008 (invited 70
  • 71. special seminar). 170. Chen YM. HIV-1 infection in Asia: How Harm Reduction Program Turn the Tide of HIV-1 Epidemic in Taiwan. Presentation in Chu St. Pierre Forum. Department of Infectious Diseases, Chu St. Pierre, The European AIDS Clinical Society (EACS). Belgium. September 9, 2008 (invited special seminar). 171. Chen YM. Emerging Infectious Disease. 2008 Global Forum for Health Leaders. November 3-4, Taipei, Taiwan. (invited speaker). 172. Chen YM. Molecular epidemiology of HIV-1 infection and evaluation of the harm reduction program in Taiwan. Biostatistics Day Symposium. November 26, 2008, Taichung, Taiwan (invited speaker). 173. Lee YM, Lin HJ, Chen YJ, Lee CM, Wang SF, Chang KY, Chen TL, Liu HF, Chen YM. Molecular Epidemiology of HCV Genotypes among Injection Drug Users in Taiwan: Identification of a new subtype 6v and th unique recombinant form_2b6v. 11 Western Pacific Congress on Chemotherapy and Infectious Diseases. (WPCCID), November 29- December 3, Taipei, Taiwan (Poster). 174. Liao CF, Wang SF, Chen YM. Analysis of the DC-SIGN-interactive th domains on the envelop glycoprotein of HIV-1 CRF07_BC. 11 Western 71
  • 72. Pacific Congress on Chemotherapy and Infectious Diseases. (WPCCID), November 29-December 3, Taipei, Taiwan (Poster). 175. Chen YM. Evaluation of the harm reduction program in Taiwan. 2008 Healthy City Symposium in Taipei. December 6-7, 2008. Taipei, Taiwan (invited speaker). 176. Chen YM. Epidemiology of HIV-1 infection and evaluation of harm reduction program in Taiwan. The Asian Administrative Meeting on HIV/ AIDS, Kunming, Yunnan, China. Organized by Ministry of Health, Labor and Welfare of Japan, March 18-19, 2009 (invited speaker). 177. Yen CH and Chen YM. Glycine N-methyltransferase affects the th metabolism of aflatoxin B1 and blocks its carcinogenic effect. 100 AACR meeting, April 18-22, Denver, 2009. (poster). 178. Chen M, Huang YC, Ko IL, Yang S, Chang YH, Huang W J-S, Yi-Ming Arthur Chen YMA. Association study of rs1447295 at 8q24 with prostate cancer in Taiwanese men. World Chinese Urological Society Meeting. Chicago, April 2009. (oral presentation). 179. Jan YR, Zhou J, Chuang SY, Wong WW, Chen YM. Impact of HBV and HCV coinfection on the Outcomes of antiretroviral treatment (ART) and disease progression in HIV-infected Patients in Taiwan. IAS 72
  • 73. (International AIDS Society Meeting), July 19-22, 2009. 180. Chen YM, Chu YT, Kao DYT, Chiang SC, Wu SC. Risk of Cancer th among People Living with HIV/AIDS (PLWHA) in Taiwan 1997-2007. 9 ICAAP, August 8-13, Bali, Indonesia. 181. Chen YM. Network of collaborating universities in health care and its education. EAIE (European Association for International Education, oral presentation and section organizer, Madrid, Spain, September 14-20, 2009. 182. Peng EY, Lyu SY, Morisky DE, Lan YC, Chen YM. Comparison of drug- using experiences among female inmates by age groups in Taiwan. 137 APHA (American Public Health Association) meeting, Philadelphia, USA, November 7-11, 2009. 183. Yang YC, Chen YM, Yeh CC, Ling MP, Wang RY, Lu CL, Chen KH, Lai JS, Lan YC. Creating a HIV-1 infection risk model as a prevention tool for Injecting drug users. Comparison of drug-using experiences among female inmates by age groups in Taiwan. 137 APHA (American Public Health Association) meeting, Philadelphia, USA, November 7-11, 2009. 184. Chen YM, Lan YC, Lyu SY. Evaluating the impact of harm-reduction program in Taiwan from 2005-2008. 137 APHA (American Public Health 73
  • 74. Association) meeting, Philadelphia, USA, November 7-11, 2009. 74