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Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
Curriculum Vitae
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Curriculum Vitae

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  • 1. ALAN SOLOMON: CURRICULUM VITAE Title: American Cancer Society Clinical Research Professor Professor of Medicine and Head, Human Immunology & Cancer Program University of Tennessee Graduate School of Medicine, Knoxville, TN Birth Date: May 16, 1933 Citizenship: United States (born New York, NY) Wife: Andrea G. Cartwright Children: David A. Solomon Joseph A. Solomon Step Children: William (Woody) Cartwright Michael A. Cartwright Office: University of Tennessee Graduate School of Medicine 1924 Alcoa Highway Knoxville, TN 37920 Tel: (865)·305·9167 Fax: (865)·305·6865 E-mail: asolomon@utmck.edu Home: GATOP 2705 Riverside Drive Knoxville, TN 37914 Tel: (865) 524-5087 Fax: (865) 523-3627 E-mail: asolomonmd@hotmail.com Education: Bucknell University 1949-1953 Lewisburg, PA BS (Biology) Duke University School of Medicine 1953-1957 Durham, NC BSM, MD Military Status: Senior Assistant Surgeon, USPHS 1960-1962 Senior Surgeon, Inactive Reserve, USPHS 1962-1983 Board 1
  • 2. Certification: Diplomat: National Board of Medical Examiners 1958 Diplomat: American Board of Internal Medicine 1964 Medical Licensure (active): Tennessee 1966- Grants and Awards: Special Fellowship 1963-1965 National Institute of Arthritis and Metabolic Diseases National Institutes of Health, USPHS USPHS Research Grant R01 CA-08354 1965-1966 Principal Investigator American Cancer Society Research Grant T-420 1967-1973 Principal Investigator National Science Foundation Research Grant GB-6036 1967-1973 Principal Investigator Research Career Development Award CA-21229 1968-1972 National Cancer Institute USPHS Research Grant R01 CA-15173 1974-1977 Co-Principal Investigator American Cancer Society Research Grant IM-430 1985-1991 Principal Investigator USPHS Research Grant R01 CA-10056 1966-2012 Principal Investigator American Cancer Society Clinical 1992-2003 Research Professorship USPHS Research Grant R21 CA-76630 1998-2000 Principal Investigator USPHS Research Grant R21 CA-82609 1999-2001 Principal Investigator USPHS (NCI) Rapid Access to Intervention 1999-2000 Development (RAID) Biologic Projects Award 049 Honors: Alpha Omega Alpha 1956 Duke University School of Medicine C.V. Mosby Award for Scholastic Excellence 1957 2
  • 3. Duke University School of Medicine First Prize, Essay for Fourth Year Medical Students 1957 New England Journal of Medicine Dr. Daniel Stats Memorial Award 1961 Editorial Board, Journal of the Mount Sinai Hospital Fellow, American College of Physicians 1968 Second Prize, Henry L. Moses Award 1970 Montefiore Hospital, NY Physician's Recognition Award 1971 American Medical Association Third Prize, Henry L. Moses Award 1972 Montefiore Hospital, NY President's Club 1981 University of Tennessee The Davison Club 1981 Duke University School of Medicine First Prize, Henry L. Moses Award 1983 Montefiore Hospital, NY Laszlo Memorial Lecturer 1984 Montefiore Hospital, NY The Founders' Society 1987 Duke University Professor of Medicine Citation in Recognition 1989 of Extraordinary Leadership and Service University of Tennessee Medical Center Who's Who in America, 4th Edition 1995 Second Prize (Clinical Category), 2000 Henry L. Moses Award Montefiore Hospital, NY First Prize (Clinical Category) 2001 Henry L. Moses Award Montefiore Hospital, NY Excellence and Leadership in Basic Science and 2005 Research Award 3
  • 4. University of Tennessee Graduate School of Medicine First Prize (Basic Science Category) Henry L. Moses Award Montefiore Hospital, NY 2009 Professional Organizations: American Federation for Clinical Research 1962-1996 American Association for Cancer Research 1963- New York County and State Medical Societies 1963-1966 American Medical Association 1963-1995 Society for the Study of Blood 1964-1966 American Society of Hematology 1964- American Association for Advancement of Science 1965- Central Society for Clinical Research 1967-1990 American College of Physicians (Fellow) 1967- American Association of Immunologists 1968- Knoxville Academy of Medicine 1968- Tennessee Medical Association 1968- Sigma Xi 1968-1980 Southern Society for Clinical Investigation 1968-1978 American Society for Clinical Investigation 1971- American Association for Cancer Education 1977-1982 American Society of Clinical Oncology 1977- International Society of Hematology 1980-1998 International Society for Experimental Hematology 1981-1995 Clinical Immunology Society 1988-2000 American Society for Investigative Pathology 2002 - Professional Assignments Since 1966: Tutor, Immunology Seminar 1968 University of Tennessee- Oak Ridge Graduate School of Biomedical Sciences 4
  • 5. Institutional Research Grant Committee 1968-1970 American Cancer Society, University of Tennessee Faculty Council 1968-1975 University of Tennessee Memorial Research Center Transfusion Committee 1969-1972 University of Tennessee Memorial Research Center and Hospital Library Committee 1970-1972 University of Tennessee Memorial Research Center and Hospital Southeastern Cancer Study Group 1970- 1980 Regional Representative, Admissions Committee 1970-1991 Duke University School of Medicine Subcommittee on Nomenclature of 1971-1973 Human Immunoglobulins International Union of Immunologic Societies Chairman 1971-1974 Institutional Research Grant Committee American Cancer Society University of Tennessee Memorial Research Center Seminar Chairman 1971-1974 University of Tennessee Memorial Research Center Graduate Faculty 1971-1988 Department of Microbiology Subcommittee on Multiple Myeloma 1971-1980 Southeastern Cancer Study Group Project Coordinator 1972-1974 East Tennessee Cancer Research Center Special Medical Committee 1973-1974 Comprehensive Health Planning, Knoxville Academy of Medicine Consulting Staff (Hematology/Oncology) 1974-1978 East Tennessee Chest Disease Hospital Research Participation Committee 1974-1977 5
  • 6. University of Tennessee-Knoxville President 1974-1977 Knoxville-Oak Ridge Associated Researchers and Clinicians in Cancer Board of Directors 1974-1996 American Cancer Society - Knox County Unit Professional Education Committee 1974-1990 American Cancer Society - Knox County Unit Membership Committee 1974-1977 American Association of Immunologists Secretary 1974-1977 Scientific Review Committee East Tennessee Cancer Research Center Chairman 1975-1977 Liaison Committee to the East Tennessee Cancer Research Center, Knoxville Academy of Medicine Subcommittee on Tumor Immunology 1975-1978 Southeastern Cancer Study Group Continuing Medical Education Committee 1975-1978 Knoxville Academy of Medicine Clinical Cancer Committee 1975-1980 University of Tennessee Medical Center at Knoxville Consultant 1976-1983 Human Cancer Diagnostics and Therapeutics Unit, Cancer and Toxicology Program, Biology Division, Oak Ridge National Laboratory Medical Director 1977-2004 Baptist Regional Cancer Center Baptist Hospital of East Tennessee Chairman 1977-1990 Oncology Committee Baptist Regional Cancer Center Consultant 1977- Center for Mechanistic Biology and Biotechnology Argonne National Laboratory 6
  • 7. Advisory Panel 1978-1980 The American Board of Medical Laboratory Immunology Research Committee 1978-1979 Tennessee Heart Association Consultant 1978-1979 Clinical Cancer Program Project Review Committee National Cancer Institute National Institutes of Health Credentials Committee, Medical Staff 1978-1980 East Tennessee Baptist Hospital Treasurer 1979-1980 Knoxville Society of Internal Medicine Clinical Cancer Program Project Review Committee 1979-1982 National Cancer Institute National Institutes of Health Chairman 1982-1983 Program Project Review Committee National Cancer Institute National Institutes of Health Institutional Review Committee 1979-1982 East Tennessee Baptist Hospital Special Committee on Blood Banks 1980-1982 Knoxville Academy of Medicine Committee on Medicine and Religion 1980-1982 Knoxville Academy of Medicine Consultant 1980-1983 Health and Safety Research Division Nuclear Division, ORNL Ad Hoc Subcommittee on Program Project Review 1982-1983 National Cancer Advisory Board Board of Scientific Counselors 1993-1995 Division of Cancer Biology, Diagnosis, and Centers National Cancer Institute, National Institutes of Health Advisory Board 1991-2002 7
  • 8. University of Tennessee Research Corporation Professional Advisory Board 1993-2000 The Wellness Community—National Editorial Board 1993- Amyloid: The Journal of Protein Folding Disorders AAI Committee on Public Affairs 1993-1995 American Association of Immunologists Cancer Center Program Strategic Planning Task Force 1994-1995 University of Tennessee Medical Center Knoxville, TN Counselor 1997-2001 The Henry Kunkel Society, Rockefeller University Hospital New York, NY ` Scientific Advisory Board, 1998- International Myeloma Foundation Research Targeting Advisory Group, 1998 American Cancer Society Harry & Elsa Jiler American 1998-2002 Cancer Society International Visiting Scientist Committee, Chairman University of Tennessee Graduate School of Medicine Scientific Advisory Board 2000-2004 Multiple Myeloma Research Foundation Medical Advisory Board 2004- Amyloidosis Research Foundation Invited Participation in Scientific Conferences since 1992: Mechanisms in B-Cell Neoplasia Conference 4/21-23/92 sponsored by the National Cancer Institute's Laboratory of Genetics, Division of Cancer Biology, Diagnosis and Centers Bethesda, MD Site-Visit Chairman, National Cancer Institute 4/29-30/92 Special Review Committee, Clinical Cancer Program Project Grant, Bethesda, MD 8
  • 9. American Cancer Society Cancernet Support Group 5/12/92 Park West Hospital Knoxville, TN 83rd Annual Meeting of the American Association 5/20-23/92 for Cancer Research San Diego, CA 25th Annual Meeting and Exposition, The American 11/15-18/92 Society of Nephrology Baltimore, MD Methodist Medical Center Staff and CME Committee 4/13/93 Oak Ridge, TN Introductory Speaker, VII International Symposium 7/11-15/93 on Amyloidosis Kingston, Ontario, Canada IVth International Workshop on Multiple Myeloma 10/2-5/93 Mayo Foundation Rochester, MN Molecular Approaches to Cancer Immunotherapy, 11/7-11/93 American Association for Cancer Research Asheville, NC Markey Cancer Center Seminar Series, 11/12/93 Chandler Medical Center, Lexington, KY 5th International Conference on Lymphocyte 2/4-6/94 Activation and Immune Regulation Newport Beach, CA Conference on Immunoglobulin Gene Expression 7/13-17/94 in Development and Disease, sponsored by The New York Academy of Sciences Montreal, Quebec, Canada 36th Annual Meeting and Exposition, 12/3-5/94 The American Society of Hematology Nashville, TN 9th International Congress of Immunology, 7/23-29/95 San Francisco, CA 9
  • 10. Session Chairman on "Major Amyloidoses", 8/20-25/95 FASEB Summer Research Conference on "Amyloid and Other Abnormal Assembly Processes" Copper Mountain, CO Vth International Workshop on Multiple Myeloma 9/10-13/95 La Baule, France Guest Lecturer commemorating the retirement of 3/23/96 Shiro Saito, MD, Dean and Professor of Medicine, First Department of Internal Medicine, School of Medicine, The University of Tokushima, Japan The Louisiana State University Medical Center 4/1/96 Seminar Series Shreveport, LA American Cancer Society Cancernet Support Group 4/16/96 Knoxville, TN Internal Medical Ground Rounds, 4/18/96 University of Arkansas for Medical Sciences Little Rock, AR The Henry Kunkel Society Meeting 5/2-3/96 The Rockefeller University New York, NY VI International Workshop on Multiple Myeloma 6/14-18/97 Boston, MA FASEB Summer Research Conference on 7/13-18/97 "Amyloid and Other Abnormal Assembly Processes" Copper Mountain, CO Center for the Study of Emerging Diseases, 11/8-12/98 International Workshop on Conformational Diseases, Ein-Boqeq, Dead Sea, Israel ACS Professors Meeting 10/10/99 White Planes, NY FASEB Summer Research Conference on 6/11-15/00 “Amyloid and Other Protein Assembly Processes” Copper Mountain, CO Henry Kunkel Society Meeting 5/2-3/01 Rockefeller University 10
  • 11. New York, NY VIIIth International Myeloma Workshop 5/4-8/01 Banff, Alberta, Canada IX International Amyloid Symposium 7/15-21/01 Budapest, Hungary FASEB Summer Research Conference on 6/15-19/02 “Amyloids and Other Protein Assembly Processes” Snowmass, CO 9th Conference on Cancer Therapy with Antibodies 10/24-26/02 and Immunoconjugates Princeton, NJ ACS Professor Meeting 10/30-11-1/03 Key Biscayne, FL X International Amyloid Symposium 4/18-22/04 Tours, France Protein Folding Disorders & Protein Therapeutics 1/11-12/05 San Diego, CA Presentations (Since 1991): “Human Light-Chain-Associated Diseases: 3/26/91 Myeloma (Cast) Nephropathy, Light-Chain Deposition Disease, and Amyloidosis” Medical Grand Rounds University of Tennessee Medical Center “Multiple Myeloma: Recent Advances in 1/16/92 Diagnosis and Treatment” Cancer Committee Multidisciplinary Conference University of Tennessee Medical Center “Malignant Lymphoma” 5/12/92 American Cancer Society-Cancernet Group Park West Hospital, Knoxville, TN “Experimental Model of Human Light-Chain- 11/16/92 Associated Renal and Systemic Diseases” 25th Annual Meeting and Exposition The American Society of Nephrology Baltimore, MD “Multiple Myeloma: Diagnosis and Treatment” 4/13/93 11
  • 12. Methodist Medical Center Staff and CME Committee Oak Ridge, TN “Research Being Conducted in The Human 6/29/93 Immunology & Cancer Program at UTMC/K” Board of Directors American Cancer Society Knox County Unit Knoxville, TN “Heavy-Chain-Associated Amyloidosis 7/11-15/93 (AH Amyloidosis)” VIIth International Symposium on Amyloidosis Kingston, Ontario, Canada “Multiple Myeloma and Related Diseases: 11/12/93 Clinical and Pathologic Implications of Monoclonal Immunoglobulins” Markey Cancer Center Seminar Series University of Kentucky Chandler Medical Center Lexington, KY “Plasma Cell Neoplasms and Amyloidosis” 1/21/94 Medical Residents Conference University of Tennessee Medical Center Knoxville, TN “Immunoglobulin Pathophysiology in 4/16/94 B-Cell Malignancies” American Cancer Society Research Professors' Meeting Santa Cruz, CA “Clinical Implications of Light-Chain Deposition” 9/13/94 Medical Grand Rounds University of Tennessee Medical Center Knoxville, TN “Update on Light-Chain-Related Diseases” 11/18/94 Medical Residents Conference University of Tennessee Medical Center Knoxville, TN “Light-Chain Amyloidosis and Deposition Diseases” 8/22/95 FASEB Summer Research Conference on "Amyloid and Other Abnormal Assembly Processes" Copper Mountain, CO Poster: “Immunoglobulin Kappa Light Chain 8/20-25/95 Framework One (FR1) Peptide is Fibrillogenic” Co-authored with Th. A. Niewold, C. Murphy, and J. Wood, 12
  • 13. FASEB Summer Research Conference on "Amyloid and Other Abnormal Assembly Processes" Copper Mountain, CO Poster: “Quantitation and Characterization of 8/20-25/95 the Binding of Thioflavin T (THT) and Congo Red (CR) to Peptide Fibrils” Co-authored with J. S. Wall, Th. A. Niewold, and C. Murphy, FASEB Summer Research Conference on "Amyloid and Other Abnormal Assembly Processes" Copper Mountain, CO “Pathologic Ramifications of Immunoglobulin 9/12/95 Deposition in Multiple Myeloma and Related Diseases” Vth International Workshop on Multiple Myeloma La Baule, France “Human Light-Chain-Associated Renal and 10/24/95 Systemic Diseases: Myeloma (Cast) Nephropathy, Light-Chain Deposition Disease, and AL Amyloidosis” Medicine Grand Rounds University of Tennessee Medical Center Knoxville, TN “Multiple Myeloma” 11/10,17/95 Healthline, Channel 12 Knoxville, TN “Clinical and Experimental Features of the Human 3/23/96 Renal and Systemic Light-Chain-Associated Diseases” Guest Lecture commemorating the retirement of Shiro Saito, MD Dean and Professor of Medicine First Department of Internal Medicine School of Medicine The University of Tokushima, Japan “Clinical and Experimental Features of the Human 4/1/96 Renal and Systemic Light-Chain-Associated Diseases” The Louisiana State University Medical Center Seminar Series Shreveport, LA “Facts About Leukemia, Lymphoma, 4/16/96 Multiple Myeloma, and Hodgkin's Disease-1995 Update” American Cancer Society Cancernet Support Group Knoxville, TN “Clinical and Experimental Features of the Human 4/18/96 13
  • 14. Renal and Systemic Light-Chain-Associated Diseases” Internal Medical Grand Rounds University of Arkansas for Medical Sciences, Little Rock, AR “Clinical and Experimental Features of the Human 5/2/96 Renal and Systemic Light-Chain-Associated Diseases” The Kunkel Society Meeting The Rockefeller University New York, NY “The Role of Aredia (Pamidronate) in Multiple 9/11/96 Myeloma and Metastatic Lytic Lesions” Chiron Therapeutics Knoxville, TN "Clinical and experimental features of the Human 2/17/97 Renal and Systemic Light-Chain-Associated Diseases" Guest Lecturer, Neuroscience Therapeutics Seminar Parke-Davis Ann Arbor, MI ”Myeloma Update” 4/16-19/98 Arizona Cancer Center Tucson, AZ "Comparison of Recombinant λ6 VL Proteins- 8/7 -11/98 Chemical and Thermal Stability Correlates with Fibrillogenesis Potential" VIII International Symposium on Amyloidosis Mayo Clinic Rochester, MN “Light Chain-Associated Conformational Diseases” 10/8-12/98 International Workshop on Conformational Diseases The Center for the Study of Emerging Diseases Ein-Boqeq, Israel “Light Chain-Associated Conformational Diseases” 1/27/99 Advances in Immunology University of Tennessee Medical Center Knoxville, TN “Immunotherapy in Patients with Light Chain 6/99 Associated (AL) Amyloidosis: Antibody-Mediated Resolution of Pathologic Deposits” Development Therapeutic Program Division of Cancer Treatment and Diagnosis 14
  • 15. National Cancer Institute Frederick, MD “Advances in the Diagnosis and Treatment 8/30/99 of Amyloid-Associated Diseases: Collaboration between the Universities of Uppsala and Tennessee” Guest Lecturer Uppsala University Uppsala, Sweden Poster: “Extramedullary Production of 9/1-5/99 AL Amyloid Precursor Proteins” VIIth International Workshop on Multiple Myeloma Stockholm, Sweden “Antibody-Mediated Resolution of Light Chain- 6/11-15/00 Associated (AL) Amyloid Deposits” FASEB Summer Research Conference on “Amyloid and Other Protein Assembly Processes” Copper Mountain, CO “Primary (AL) Amyloidosis: Diagnostic, Prognosis 7/15-21/01 and Therapeutic Strategies” Keynote Lecturer IXth International Symposium on Amyloidosis Budapest, Hungary “Primary (AL) Amyloidosis: Diagnostic, Prognostic, 8/17/01 and Therapeutic Strategies” Department of Pathology University of Tennessee Medical Center, Knoxville Knoxville, TN “Immunotherapy of Patients with Primary (AL) 4/3/02 Amyloidosis: Antibody-Mediated Resolution of Pathologic Deposits” Drug Development Group Division of Cancer Treatment and Diagnosis National Cancer Institute Rockville, MD “Primary Amyloidosis” 7/30/02 Department of Medicine Grand Rounds University of Tennessee Medical Center, Knoxville Knoxville, TN “Immunotherapy in Primary (AL) Amyloidosis using 8-24-02 15
  • 16. Amyloid-Reactive Monoclonal Antibodies” Guest Lecturer 9th Conference on Cancer Therapy with Antibodies and Immunoconjugates Princeton, NJ “Amyloid: The Curse of Old Age” 9-26-03 University of Tennessee Science Forum University of Tennessee Knoxville, TN “The Amyloidoses: A Medical Curse “ 10-26-03 Council of Scientific Writers Knoxville, TN “Amyloid-Reactive Antibodies as Novel 10-30-03 Immunotherapeutic Agents for Patients with Primary (AL) Amyloidosis” American Cancer Society Professors Meeting Key Biscayne, FL “Immunotherapy in Systemic Primary (AL) Amyloidosis 2-25-04 using Amyloid-Reactive Monoclonal Antibodies” Forum, University of Tennessee Department of Biochemistry Molecular Biology Knoxville, TN “Immunotherapy in AL Amyloidosis” 4-21-04 Xth International Symposium on Amyloid and Amyloidosis Tours, France “Amyloid-Reactive Antibodies as Novel 10-26-04 Immunotherapeutic and Imaging Agents for Patients with Primary (AL) Amyloidosis” Hematology/Medical Oncology Grand Rounds Memorial Sloan-Kettering Cancer Center New York, NY “Demonstration of the Efficacy of Passive 1-11-05 Immunotherapy of Peripheral Amyloid Diseases in Animal Models” San Diego, CA “War on Amyloid: Diagnostic and Therapeutic 4-11-06 Strategies” Internal Medicine Ground Rounds 16
  • 17. The University of Tennessee Graduate School of Medicine Knoxville, TN Appointments: Intern 1957-1958 Mount Sinai Hospital, NY Assistant Resident in Medicine (Dr. L. Leiter) 1958-1959 Montefiore Hospital, NY Assistant Resident in Medicine (Dr. A. B. Gutman) 1959-1960 Mount Sinai Hospital, NY Clinical Associate 1960-1962 Metabolism Service (Dr. J.L. Fahey) National Cancer Institute, National Institutes of Health Chief Resident in Medicine (Dr. A. B. Gutman) 1962-1963 Mount Sinai Hospital, NY Research Assistant in Hematology 1963-1965 (Dr. L. R. Wasserman) Mount Sinai Hospital, NY Guest Investigator (Dr. H. G. Kunkel) and 1963-1965 Assistant Physician The Rockefeller University, NY Assistant Attending Hematologist 1965-1966 Mount Sinai Hospital, NY Associate Physician and Guest Investigator 1965-1966 The Rockefeller University, NY Associate Research Professor 1966-1969 University of Tennessee Memorial Research Center and Hospital Knoxville, TN Research Professor 1970-1978 University of Tennessee Memorial Research Center and Hospital Knoxville, TN Clinical Professor 1972-1980 Department of Medicine, Clinical Education Center University of Tennessee Center for Health Sciences Knoxville, TN 17
  • 18. Professor of Medical Biology 1978-1980 Department of Medical Biology, Memorial Research Center University of Tennessee Center for Health Sciences Knoxville, TN Professor of Medicine 1981- Department of Medicine University of Tennessee Center for Health Sciences Knoxville, TN Head, Human Immunology & Cancer Program 1988- Department of Medicine University of Tennessee Medical Center Knoxville, TN Guest Investigator 1990- Argonne National Laboratory Argonne, IL American Cancer Society Clinical Research Professor 1992- Hospital Staff Appointments (Knoxville, TN): Active Medical Staff 1966- Department of Medicine University of Tennessee Medical Center Active Medical Staff 1975- Department of Medicine (Hematology/Oncology) Baptist Hospital of East Tennessee Courtesy Medical Staff 1975-2000 Department of Medicine (Hematology/Oncology) Fort Sanders Regional Medical Center Courtesy Medical Staff 1975-1993 Department of Medicine (Hematology/Oncology) East Tennessee Children's Hospital Courtesy Medical Staff 1976-1998 Department of Medicine (Hematology/Oncology) St. Mary's Medical Center Other Assignments and Honors: Board of Visitors, College of Nursing 1997- University of Tennessee 18
  • 19. Board of Visitors 2004- University of Tennessee Department of Religious Studies Advisory Board, Clarence Brown Theater 2000- University of Tennessee James L. Clayton Award, Knoxville Museum of Art 2007 Knoxville, TN 19

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