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Curriculum Vita
 

Curriculum Vita

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    Curriculum Vita Curriculum Vita Document Transcript

    • CURRICULUM VITAE Name: Songqing He Email :hesong@musc.edu Job Title : postdoctoral fellow Research Interesting Transplantation, Cancer, Immunology, Gene Therapy and Clinical Surgery. Education: 1989.9 – 1994.6 M.D. Department of Medicine, Guilin Medical College, P. R. China 1997.8 – 1999. 6 M.Sc. Hepatic Surgery Center Affiliated Tongji Hospital,Tongji Medical University, P. R. China (Advisor: Prof. Xiaoping Chen.) 2000.9 –2003. 6 Ph.D. Hepatic Surgery Center Affiliated Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, P. R. of China (Advisor: Prof. Xiaoping Chen.) Postdoctoral Training: 1994- 1997 Resident, the affiliated hospital of Guilin Medical College, Guilin, P. R. China 1999- 2000 Instructor, the affiliated hospital of Guilin Medical College, Guilin, P. R. of China 2003- 2005 Instructor, Hepatic Surgery Center, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,wuhan, P. R. of China. Sep.2005—Sept.2006 Post-Doctoral Research Fellow in the Department of Medicine, Transplant Research Program, UC Davis Oct.2006—May.2007 Post-Doctoral Research Fellow in Department of pharmaceutical sciences, MUSC, Charleston, SC June.2007-Now Post-Doctoral Research Fellow in Department of Microbiology and Immunology, Children's Research Institute, Medical University of South Carolina, Charleston, SC 29425, USA. Awards and Honors: 1. 1990-1993 An award for top student from Guilin Medical College, Guilin P. R. China 2. 1993. An award for top student from Guangxi Province Government, P. R. of China 3. 1994 Excellent Graduate Student Award from Guangxi Province Government, P. R. of China 4. 2003 Ph.D. Thesis Award from the Huazhong University of Science and Technology, Wuhan, P. R. China 5. 2005 An Award for A Progress of National Science and Technology from Ministry Of Education focus on Liver Cancer Therapy.
    • Technical Skills Ι Animal Models: Liver transplant model in Rat and mouse (small-for-size and full size) Partial hepatectomy and ischemia/reperfusion model Experimental nude mice In situ hepatocellular carcinoma model Mouse heart transplantation (abdomen and neck) Heart ischemia/reperfusion model ΙΙ Molecular Biology Western-blot analysis In situ hybridization RT-PCR EMSA ΙΙΙ Immunohistochemistry: ΙV Cell culture technique Publication 1.He SQ, Hasibur Rehman, Gong MG,et.al. Inhibiting survivin expression Enhances TRAIL-induced tumoricidal activity in human hepatocellular carcinoma via cell cycle arrest. Cancer Biol Ther 2007 May 16;6(8). 2.Zhang Y, Venugopal SK, He S, Liu P, Wu J, Zern MA. .Ethanol Induces Apoptosis in Hepatocytes by a Pathway Involving Novel Protein Kinase C Isoforms. Cellular Signal 2007 Jul 27. 3. He SQ, Zhang YH, Venugopal SK, Dicus CW, Perez RV, Ramsamooj R, Nantz MH, Zern MA, Wu J.Delivery of anti-oxidative enzyme genes protects against ischemia/reperfusion liver injury in mice. Liver Transpl. 2006 Dec;12(12):1869-79. 4.Chen XP, Qiu FZ, Wu ZD, Zhang ZW, Huang ZY, Chen YF, Zhang BX, He SQ, Zhang WG. Effects of Location and Extension of Portal Vein Tumor Thrombus on Long-Term Outcomes of Surgical Treatment for Hepatocellular Carcinoma. Ann Surg Oncol. 2006 Jul;13(7):940-6. 5.Chen XP, Zhang ZW, Zhang BX, Chen YF, Huang ZY, Zhang WG, He SQ, Qiu FZ. Modified technique of hepatic vascular exclusion: effect on blood loss during complex mesohepatectomy in hepatocellular carcinoma patients with cirrhosis. Langenbecks Arch Surg. 2006 Jun;391(3):209-215. 6.Chen XP, He SQ, Zhao X, Huang ZY, Li CH. Chinese medicine Extractum trametes robiniophila murr augment tumor necrosis factor related apoptosis-inducing ligand induced apoptosis in human hepatic cancer cell lines. Chinese journal of surgery. 2005 Dec; 43(23):1524-7. 7.He SQ, Chen Y,Chen XP, et al. Antitumor effects of soluble TRAIL in human hepatocellular carcinoma.J Huazhong Univ Sci Technolog Med Sci. 2005;25(1):51-4. 8.Huang ZY, He SQ, Xiao ZY, Wu CD, Li CH, Chen XP. Hepatic angiomyolipoma demonstrating similar imaging characteristics as hepatocellular carcinoma: one case report.J Huazhong Univ Sci Technolog Med Sci. 2005;25(5):615-6, 618. 9.Xiao ZY; Chen XP, He SQ, HUANG ZY, LI L. Expression of TRAIL and TRAILR in human
    • hepatocellular carcinoma and its therapeutic significance. Chinese Journal of General Surgery 2005-08-014 10.Huang ZY, Chen XP, Wu ZD, He SQ. Nonresectable huge hepatocellular carcinomas treated with cryosurgery in combination with intraoperative transarterial chemoembolization. Journal of Abdominal Surgery 2005-06-013 11.Xiao ZY, Chen XP, He SQ, Huang ZY, LI L. ANTITUMOR EFFECT OF TRAIL IN HUMAN HEPATOCELLULAR CARCINOMA. Journal of Hepatobiliary Surgery 2005-03-027 12.Zhao X, Chen XP, He SQ, et al. THE THERAPEUTIC EFFECT OF TRAIL AND TRAILR IN TREATMENT OF CHEMORESISTANT HEPATOCELLULAR CARCINOMA CELLS. Journal of Hepatobiliary Surgery 2005 13.Zhao X, Chen XP, He SQ, et al. Apoptosis of chemoresistant hepatocellular carcinoma cells synergisti cally induced by TRAIL and adriamycin. Digestive Surgery.2005 14.He SQ , Chen XP, Zhang WG, Wang HP, Wang Q.Tumor necrosis factor related apoptosis-inducing ligand induces apoptosis and sensitizes resistant hepatic cancer cells to chemotherapy. Chinese journal of Hepatology 2004 12(8):456-9. 15.Wang SF, Chen XP, Zhang WG, He SQ, Chen DF. Expression of peroxisome proliferator-activated receptor alpha in human normal liver and hepatocellular carcinoma. Chinese journal of Hepatology 2004 Jan; 12(1): 52-3. 16.Wang HP, Chen XP,Ding L,He SQ. Correlation between hypoxia-inducible factor-1α and vascular endothelial growth factor expression in cirrhosis and hepatocellular carcinoma. Chinese Journal of Experimental Surgery 2004-03-018. 17.Chen XP, He SQ , Wang HP, Zhao YZ, Zhang WG. Expression of TNF-related apoptosis-inducing Ligand receptors and antitumor tumor effects of TNF-related apoptosis- inducing Ligand in human hepatocellular carcinoma. World J Gastroenterol 2003 Nov; 9(11): 2433-40. 18. Wang HP, Chen XP, Ding L, He SQ , Ali M, Li DH, Zhang WG. Hepatitis B x protein activated vascular endothelial growth factor expression through hypoxia inducible factor-1 pathway. The Chinese Journal of Oncology 2003 Sep; 25(5): 433-6. 19. He SQ, Chen Y, Chen XP, Zhao YZ, et al . Effects of TRAIL gene therapy on human hepatocellular carcinoma. Chinese journal of experimental surgery 2003, 8,708-710. 20.He SQ, Chen Y, Chen XP, Zhang WG, Wang HP, Zhang BX . Interleukin-12 enhanced tumor necrosis factor related apoptosis-inducing ligand TRAIL-induced apoptosis in human hepatocellular carcinoma by inhibiting expression of survivin. Chinese journal of surgery 2003 Jun; 41(6): 453-7. 21.Wang HP, Chen XP, He SQ, Ding L. Effects of regulatory endoplasmic HBX expression on hepatic cell apoptosis. Chinese journal of Hepatology 2003 Jul; 11(7): 440. 22.He SQ , Chen Y, Chen XP, Zhang WG, Wang HP, Zhao YZ, Wang SF. Antitumor effects of soluble TRAIL in humanhepatocellular carcinoma. The Chinese Journal of Oncology 2003 Mar; 25(2): 116-9.
    • 23. He SQ , Chen XP.Zhao YZ, et al. Expression Profiles of TRAIL Receptors and their Clinical Significance in Human Hepatocellular Carcinoma. The Chinese-German Journal of Clinical Oncology (English) 2003, 2, 25-29. 24. He SQ, Chen XP.The relationship of Interleukin-12 、 Interleukin-2 and soluble IL-2 receptor in human hepatocellular carcinoma. Chinese journal of general surgery 2002,4: 211-213. 25.He SQ , Chen XP. Expression and clinical significance of soluble Interleukin-2 receptor in human hepatocellular carcinoma. Chinese journal of Hepatobiliary surgery 2001 , 3 : 214-216. 26.He SQ, Chen XP. Expression and clinical significance of Interleukin-12 in human hepatocellular carcinoma. The journal of Hepatobiliary surgery 1999, 7:46-48. Reviews: 1. He SQ, Chen XP.TRAIL 、TRAIL receptors and anticancer effect. Chinese journal of surgery 2002, 4:311-313. 2. He SQ, Chen XP.Interleukin-12 and its antitumor effect. Chinese journal of surgery 2000, 3:311-313.