Biology 327 – Microbial Pathogenesis and Human Immunology
CEDAR CREST COLLEGE
Biology 327 – Microbial Pathogenesis and Human Immunology
Course Syllabus - Part I: Overview
Instructor: Dr. Amy J. Reese
Office: Science Center 110
Phone: 610-437-4471, x3517
Office Hours: Monday 1 – 1:50 pm, Tuesday 4 – 4:50 pm, Wednesday 1 – 1:50 pm, Thursday 4 – 4:50
pm, and Friday 10 – 10:50 am. Other hours by appointment.
GENERAL COURSE INFORMATION
Biology 327: Microbial Pathogenesis and Human Immunology, 4 credits (3 if not taking lab)
Course website: http://www2.cedarcrest.edu/academic/bio/areese/index.html
Course Prerequisites: BIO 227, 231 and 222 or permission of the instructor
This course will introduce the microorganisms responsible for many common diseases and the
ways in which the human body can protect itself against these diseases. Topics include
immunology, bacteriology, virology, mycology, parasitology, and microbial pathogenesis.
Lectures, laboratory work, current events, literature research, individual and group projects will
be integral parts of this course.
• Marjorie Kelly Cowan and Kathleen Park Talaro, Microbiology: A Systems Approach, 1st ed.,
McGraw Hill, 2006 or M. T. Madigan, J. M. Martinko, J.M. and J. Parker, Brock Biology of
Microorganisms, 10th Ed., Prentice Hall, 2003 (use of one of these texts is highly
recommended for a resource).
• Marjorie Kelly Cowan, The Microbe Files, Benjamin Cummings, 2002 (required).
• Philip M. Tierno, The Secret Life of Germs: Observations and Lessons from a Microbe
Hunter, Atria, 2001 (required).
• Lecture 3 hours per week in 212 Alumnae Hall
• Laboratory 3 hours per week in Oberkotter Center for Health and Wellness – lab 2
Bio 327 Syllabus – Part I: Overview 1
• The specific schedule for lectures can be found on the separate handout Biology 327,
Microbial Pathogenesis and Human Immunology; Course Syllabus – Part II: Lecture
Schedule, Assignments & Policies.
• The specific laboratory schedule can be found on the separate handout Biology 327,
Microbial Pathogenesis and Human Immunology; Course Syllabus – Part III: Laboratory
Schedule, Assignments & Policies.
At the successful completion of the course, the student should be able to:
1. Describe the different types of pathogens, classical symptoms and likely affected body sites.
2. Discuss the specific health risks associated with particular groups based on age, location, leisure
activities, health status, pets, and previous medical history.
3. Understand basic immunology and the interactions between host and pathogen.
4. Understand issues of commensal flora, organism transmission, and portals of entry.
5. Become familiar with common terminology associated with medical microbiology.
6. Discuss preventions, precautions, vaccinations, community health, cultural issues, biohazard
levels, and the role of the media in issues of human health.
7. Learn various laboratory methods appropriate for clinical or research applications of medical
8. Understand epidemiology, concepts of pathogenicity, virulence, disease mechanisms, antibiotic
resistance, and types of disease outbreaks.
9. Describe roles of acute, chronic, symptomatic, asymptomatic/subclinical, and reactivation in
10. Be familiar with approaches to diagnosis, case study analysis, and basic treatment concepts.
COURSE OUTCOMES & ASSESSMENT
Successful Course Completion Outcomes:
1) Demonstrate the ability to engage in critical analysis and qualitative reasoning.
- Students will study the patterns of common infectious disease pathogens and affected body sites
- The students will practice and apply their skills with new case studies and know what pieces
systematically to look for and how to predict causative microbial agents and appropriate
2) Demonstrate the ability to understand and respond to issues of local, national, and global significance.
- The student will learn critical analysis skills for addressing microbiology and microbial
pathogenesis portrayed in the general public media at the local, national, and global levels.
- Students will practice articulating the science behind such material in discussion and presentation
format to address current medical microbiology.
Bio 327 Syllabus – Part I: Overview 2
1. Students will take 3 major lecture exams and a comprehensive final exam on the content areas.
2. Students will prepare for and participate in regular discussions on current events, case studies,
and related course topics.
a. Each student should prepare at least one typed page of discussion points with references
for each discussion.
b. Discussion preparation assignments should include an introductory paragraph, data or
material collected with references, and a summary paragraph to wrap up and conclude
information gathered and prepared for the class discussion.
c. During discussions, each student should plan on verbally contributing at least one point
of prepared and referenced material towards each discussion.
d. Additional points raised during the discussion should be added by hand to the prepared
page, and both pieces submitted at the end of class as a part of discussion preparation.
These will be assessed and returned to the students for further study.
3. Students will research, write, and present an analysis and critique of an account of microbial
pathogenesis or human immunology in the local, national, or global news or TV coverage.
Further details will be discussed in class. Completion of the assignment should include:
a. the original article with full source documentation
b. any related follow up stories
c. a report with the above two parts, presentation of microbiology research using texts, CDC
information, primary literature and other reliable sources, and a critical analysis of the
science presented and implied in the article
d. a one-page lay description of the issue that can also be presented at the annual Cedar
Crest College Health and Wellness Conference
4. Four quizzes and an assignment will be given in the laboratory to assess the student ability to
understand the methodology and data interpretations of the techniques covered in the laboratory.
STUDENT ASSESSMENT & EVALUATION
Grading & policies:
500 points Lecture
300 points Laboratory work
200 points Cumulative final lecture exam
See separate handouts Biology 362 – Course Syllabus – Part II: Lecture Schedule, Assignment &
Policies and Biology 362 – Course Syllabus – Part III :Laboratory Schedule, Assignments &
Policies for grading breakdowns and policies.
Final A A- B+ B B- C+ C C- D+ D F
grade 93- 90- 87- 83- 80- 77- 73- 70- 67- 60- <60
% 100 92.9 89.9 86.9 82.9 79.9 76.9 72.9 69.9 66.9
Bio 327 Syllabus – Part I: Overview 3
STUDENT RESPONSIBILITIES AND COURSE POLICIES
Attendance and Academic policies:
1. You are expected to attend lecture, be at class on time and as scheduled, not leave early, and not
to disrupt the class. Unexcused absences/behavior may result in a 10% reduction of the total
lecture grade. Unexcused absences for lecture exams or finals will result a zero for that exam.
2. Laboratory attendance is mandatory by college policy. Each unexcused absence will result in a
10% reduction of your total laboratory grade. Unexcused absences on the day of a practical will
result in a zero for that exam.
3. In the unfortunate event of an unplanned absence due to a personal or family medical emergency,
you must contact the Dean of Student Affairs (Joan Laffey: 610-437-4471, x3371;
email@example.com) to obtain appropriate documentation for an excused absence. These
offices will contact me. You should also contact me about the situation and to make alternative
4. I fully support the Honor Code philosophy, the statement of Academic Integrity, the statement
against Academic Dishonesty or Plagiarism, and the Classroom Protocol, including appropriate
behavior and respect for instructors and classmates, that are set out by Cedar Crest College’s
Academic Policies and Services and the Community Standards for Academic Conduct.
5. Refer to the separate laboratory and lecture syllabi for further details, policies, and procedures.
1. Disabilities Services
o Students with disabilities who wish to request accommodations should contact the
Advising Center and visit the site http://www2.cedarcrest.edu/acadadvising/ada_file.html
within the first two weeks of class.
2. Academic Support
o The Advising Center provides many resources, such as study skills resources and peer
tutoring, through their website http://www2.cedarcrest.edu/acadadvising/index.html or on
campus site in the Administration Bldg, room 213, or by phone at 3484.
Bio 327 Syllabus – Part I: Overview 4
STRATEGIES FOR SUCCESS
1. Do come to class and lab ready to participate.
- Read assigned text material before class to get an idea of the terminology
- Review notes on a regular basis to be prepared to build on that material
- Review notes from previous classes before the next class
- Often, you’ll be given particular material to prepare to discuss in the next class
- Know what lab tests you’ll be doing that day and why when you come to lab
2. Do ask for help if you are having trouble.
- If you are having troubles preparing for the course, email me or visit during office hours.
The earlier in the course, the better.
- Find a study-buddy and compare, review, and revise notes early and often.
3. Do make comprehensive connections, which goes beyond memorization.
- Use homework assignments to help review and connect material.
- Memorization is step one. Connection of the material and concepts is step two.
- Think of it this way. A recital is like memorization and you practice specifically for it. But
science is always changing, I want you to learn to sightread!
4. Do regularly attend classes
- You can read the book (and you should), but you wouldn’t want to rely on the book alone.
- In class we’ll highlight the points that you should focus on. I test from my class notes.
- Tips and key information may also be given in class.
- Besides, I say and do silly things in class that you don’t want to miss!
5. Do study every day and along the way!
- Avoid “binge studying” such as trying to do everything the night before. There is simply too
much valuable information and too many applications to do this.
- If you practice, you’ll know where you have troubles before the exam.
- Write your own test questions to help you review one day, try to answer them the next.
- Flash cards may be good for some, but they are only a start to memorization.
- Study with someone else (see if s/he can answer your questions), it helps with connections
and makes it fun.
- Try studying at the same time every day.
- Ideally, you review new notes daily, and look back over old ones so you keep adding one. If
you are really doing this, you could take an exam at any point in time. Make this method
Commit to trying one new study tip this semester:
Bio 327 Syllabus – Part I: Overview 5
Exam/Assignment etc. Points possible Points scored
Lecture Discussion 1 10
Lecture Discussion 2 10
Lecture Discussion 3 10
Lecture Discussion 4 10
Lecture Discussion 5 10
Lecture Discussion 6 10
Lecture Discussion 7 10
Lecture Discussion 8 10
Lecture Discussion 9 10
Lecture Discussion 10 10
Lecture exam 1 100
Lecture exam 2 100
Lecture exam 3 100
Research project paper 75
Research 1-page description 25
Lecture total 500
Lab quiz 1 40
Lab quiz 2 40
Lab quiz 3 40
Lab quiz 4 40
Lab assignment 40
Lab total 300
Final exam 200
Course total 1000
______/1000 x 100 = _________
Note: The above scoring does not take into consideration if labs or lecture policies are violated and
result in a deduction of points.
Bio 327 Syllabus – Part I: Overview 6