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    BIOLOGICAL BASIS OF DISEASES.doc BIOLOGICAL BASIS OF DISEASES.doc Document Transcript

    • BIOLOGICAL BASIS OF DISEASES 8 ECTS credits 3rd year- 1st semester Undergraduate Required 32 h/week Lectures: 29 h/week in Turkish Total 4 weeks and Clinical practice: 3 h/week 2 days Contact: M. Reşat Özercan, Necip İlhan Aims and Objectives of the Course This course aims to introduce the students with some basic themes related to all disciplines before the students start learning the pathophysiology of the diseases of a particular system in the body. These themes include cell and tissue damage, apoptosis, autocoids, oedema, thrombosis-embolism, shock benign-malign tumor development, environmental diseases, genetic diseases, viral, bacterial, fungal, parasiter diseases and intoxications. The knowledge of basic pharmacology including pharmacodynamics and pharmacokinetics and autonom pharmacology is also implemented in this course before learning systematic pharmacology. Course contents • Introduction to pharmacology: Classification of drugs, administration of drugs, pharmacokinetics (absorption, distribution, metabolism and excretion), pharmacodynamics (mechanisms of action, drug-receptor interactions, dose-concentration relation, drug-drug adverse and toxic effects of drugs), pharmacogenetics, theraupetic drug monitoring, postmarketing surveillance • Autonom system drugs: Cholinergic, anticholinergic, adrenergic, antiadrenergic drugs, drugs related to nonadrenergic-noncholinergic system, ganglion blockers • Cell-tissue damage: Causes, physiopathology, types, alterations in the enzyme systems, apoptosis, pathological depositions inside the cell, causes of cellular aging, free radicals, primary-secondary wound healing • Oedema: Pathogenesis and pathology, fluid accumulation inside internal spaces, congestion- hyperemia, fluid-electrolyte • Formation of thrombosis--embolism: Pathogenesis of thrombosis and embolism, pathogenesis of infarction • Shock: General overview, types • Genetic diseases: Etiology, congenital malformations • Benign and malign tumors: Introduction to neoplasia, classification of tumors and their characteristics, molecular basis of cancer, chemical carcinogenes, radiation carcinogenesis, radiation-health connection, ecology, pathophysiology of acute radiation syndrome, enzyme markers of cancer, tumor markers, cytotoxic drugs • Viral, bacterial, fungal and parasiter diseases: Pathopysiology, introduction to viral, bacterial, fungal and parasiter diseases • Intoxications: General principals for the treatment of acute intoxications, antagonists and chelator agents, pestisits and their effects on health • Integrated practice: Introduction to the pharmaceutical forms of drugs, clinical case discussion (presentation of a patient with an autoimmune or allergic disorder). Microscopic examination of cell necrosis and thrombosis--embolism • Basic principles of anamnesis, characteristic of pediatric anamnesis, characteristic of neonatal examination, clinical approach to children • Anamnesis and physical examination in children Assessment Methods One written exam is scheduled at the end of the whole course. Prerequisite/ Recommended
    • None Textbook/Recommended Reading 1. Prof.Dr. Oğuz Kayaalp. Tıbbi Farmakoloji, Hacettepe Taş Kitabevi (2002) 2. Prof.Dr. Uğur Çevikbaş (Çeviri Ed.) “Robbins Basic Pathology (Temel Patoloji)”, Nobel Tıp Kitapevleri, (2003) 3. Temel Biyokimya 4. Thompson and Thompson, (Çeviri Kurulu) Tıbbi Genetik, Güneş Kitabevi (2005) 5. J.M. Connor, M.A. Ferguson-Smith, Essential Medical Genetics, Blackwell Scientific (1992) 6. Cura A., “Pediatrik Propedotik: Fizik Bakı ve Semptom Bilgisi”, (2001 ) 7. Tunçbilek E, Yurdakök M, Coşkun T,Çocuk sağlığı propedotik ,Hacettepe yayınları INFECTION 301C rd st 8 ECTS credits 3 year- 1 semester Undergraduate Required 32 h/week Lectures: 28 h/week in Turkish Total 4 weeks Clinical-integrated practice: 4 h/week Contact: Hakkı Engin AKSULU, Adnan SEYREK Aims and Objectives of the Course This course aims to introduce the students with some basic themes related to all disciplines before the students start learning the pathophysiology of the diseases of a particular system in the body. These themes would include cell and tissue damage, apoptosis, inflammation and inflammatory mediators, oedema, etiology and mechanism of inflammation, basic immunological mechanisms and pathohysiology of infectious diseases, antibiotherapy, rational pharmacotherapy and guides to good prescription. Course Contents • Viral, bacterial, fungal diseases: Pathopysiology, introduction to chemotherapy and antibiotics, antiviral drugs, antifungal drugs. • Diseases of parasite (Amebiasis, toxoplasmosis, cestods, trematods and malaria), pathopysiology chemotherapy and to be protection. • İmmunological disorders: Basic immunological mechanisms, immunological tolerance, examples of cellular immune response, autoimmunity, pathology of autoimmune diseases, clinical approach to immune failure, diagnostic tests for immune system disorders, immunomodulator drugs, • Allergic diseases: Pathophysiology of allergic diseases in children and adults, risk factors in allergic diseases and their prevention, drug allergy-antiallergic drugs, acute phase reactants • Acute-chronic inflammation: Causes, signs and types of inflammation, inflammatory mediators- autocoids, drugs related to autocoids (antagonists of histamine and serotonine, eicosonoids and nonsteroidal antiinflammatory drugs) • Integrated practice: Introduction to the pharmaceutical forms of drugs, clinical case discussion (presentation of a patient with an autoimmune or infectious disorder) Assessment Methods One practice exam is performed during the course and one written exam is scheduled at the end of the whole course. Prerequisite/ Recommended None Textbook/Recommended Reading 1. Katzung, B. G., “Basic & Clinical Pharmacology”, McGraw-Hill, (2001) 2. Kumar V., Cotran R.S., Robbins S.L., (Çeviri Ed. Çevikbaş U.), “Robbins Basic Pathology (Temel
    • Patoloji)”, Nobel Tıp Kitapevleri, (2003) 3. Murray R. P, Rosenthal S. K. Medical Microbiology. Mosby. 4. Ustaçelebi Ş.Temel ve Klinik Mikrobiyoloji.Güneş Kitabevi 5. Kayaalp O. Tıbbi Farmakoloji. Hacettepe Taş Kitabevleri. CIRCULATORY AND RESPIRATORY SYSTEMS 3rd year-2nd 8 ECTS credits Undergraduate Required semester 127 h/4weeks Lectures: 105 h/4weeks in Turkish Total 4 weeks Clinical-integrated practice: 22h/4weeks Contact: Ilgın KARACA, Akın BALCI Aims and Objectives of the Course This course aims to teach the students pathophysiology, clinical signs, physical examination findings, laboratory findings and pharmacological treatment of diseases related to cardiovascular and respiratory systems. Course contents • Atherosclerosis: aetiology, predisposing risk factors, pathology and biochemical markers • Atherosclerotic heart disease: clinical evaluation of coronary artery disease, Acute coronary Sendrome, myocardial infarction, pathology of ischaemic heart disease, • Antihyperlipidemic drugs • Congestive heart failure: clinical and laboratory findings, treatment • Hypertension: clinical evaluation of the hypertensive patient, antihypertensive drugs • Arrhythmias: arrhythmogenesis, mechanism of cardiac aritmy, clinical and electrocardiographic findings of most common cardiac arrhythmias, • Bradicardia, tachicardia • Signs and symptoms in cardiac disease • Valvulary heart disease: pathophysiology, clinical and laboratory findings of rheumatic fever, valvulary heart disease and their treatment • Diseases of the myocardium, endocardium and pericardium: pathophysiology and clinical findings of the cardiomyopathies, endocarditis and pericarditis • Congenital heart diseases(Siyonotic and non siyanotic): congenital heart diseases most common in childhood and adults and treatment modalities • Diseases of respiratory system: pathophysiology, clinical and laboratory findings of infectious/noninfectious pulmonary diseases in childhood and adults, drugs used in the treatment of these diseases • Tubercolose and laboratory findings and treatment • Astma bronshiale symtoms and treatment • Intersitsy lung disease • Kronic obstrictive lung disease • Bronshiectasi • Torasic Outlet Sendrome • Deformty of torax • Pulmonary embolism diagnosis and treatment • Diseases of pleura: pathophysiology, clinical signs and treatment • Orthomyxovirus, Paramyxovirus, Herpes virus, Hepatit viruses Assessment Methods Two clinical practice exams during the course and one written exam at the end of the course are
    • scheduled. Prerequisite/ Recommended None Textbook/Recommended Reading 1. Braunwald E., “Heart Disease, A Textbook of Cardiovascular Medicine”, 6th edition, McGraw- Hill, (2001) 2. Ravel R., “Clinical Laboratory Medicine”, 6th edition, Mosby Inc., (1995) 3. Burtis C.A., Ashwood E.R., “Tietz Textbook of Clinical Chemistry”, 3rd edition, WB Saunders Company, (1999) 4. Kaplan L.A., Pesce A.J., Kazmierczak S.C., “Clinical Chemistry: Theory, Analysis and Correlation”, 4th edition, Mosby Inc., (2003) 5. Henry J.B., “Clinical Diagnosis and Management by Laboratory Methods”, 20th edition, WB Saunders Company, (2001) 6. Anderson S.C., Cockayne S., “Clinical Chemistry: Concepts and Applications”, The McGraw Hill Companies, (2003) 7. Murray C.F., Nadel J.A., “Textbook of Respiratory Medicine”, WB Saunders Company, (2000) 8. Murray P.R., Rosenthal K.S., Kobayashi G.S., Pfaller M.A, “Medical Microbiology”, Mosby Inc, (2002) 9. Park M.K., “Pediatric Cardiology for Practioners”, 4th edition, Mosby Co., (2002) 10. Garson A., Bricker J.T., “The Science and Practice of Pediatric Cardiology”, 2nd edition, Williams and Wilkins Co., (1998) 11. Fıshman’s,” Pulmonary disease and disorders” 2001 DIGESTIVE SYSTEM 3rd year- 6 ECTS credits Undergraduate Required 2nd semester 95 h Lecture: 95 h in Turkish Total 3 weeks Lectures: Laboratory practices: Pathology Infectious diseases Pathology Pharmacology Thoracic Surgery Pharmacology Internal Medicine Nuclear Medicine PBL Pediatrics Parasitology General Surgery Radiology Contact: Yavuz Selim İlhan, İbrahim Özercan Aims and Objectives of the Course
    • This course aims to teach the students fallowing topics; Gastroenteric system and hepatobilier systems` diseases and their surgical treatments; disease of organs and their clinical features, etiopathogenesis, pathology; drugs affecting these systems and the pharmacological features. Course contents ● Abdominal examination ● Acute abdomen ● Dispepsia, Nausea , Vomiting ● Abdominal pains ● Pharmacology of enteric nervus system ● Approach to Hepatic mass ● Diseases of eusophagus ● Gastritis, Peptic ulcus, Pylor stenosis ● The Syndrome of Malabsorbsion ● Stomach tumors ● Peptic ulcus and it’s complications ● Treatment of peptic ulcus ● Gastrointestinal system’s bleedings ● Trauma of abdomen ● Diseases of small intestine ● Hepatic cirrhosis and complications ● Abdominal hernias ● The inflammatory disease of intestines ● Acute appendicitis ● İleus ● Tumor of small and large intestine ● The examination of rectum and diseases of perianal area ● Lacsatives and Purgatives ● Anti-diarrheatic drugs ● Surgical infections, asepsia, antisepsia ● Gastroenteritis ● Cancer of the Gastrointestinal system ● The methods of nuclear medicine of gastrointestinal system ● Emetic sand anti-emetic drugs ● Desorders of esophagus motility ● Achalasia and diverticules of esophagus ● The drugs which used for the treatment of gastrointestinal system infections and parasites ● Parasites at immune deficiency ● Acute hepatitis ● Chronic hepatitis ● Hepatic cirrhosis and complications ● Hepatic tumors ● Metabolic and nutritional hepatic disease ● Jaundices ● Ascites ● Radiological practice of digestive system ● Bacterial and parasitic disease of hepar
    • ● Hookworms ● Radiology of digestion tube ● The hepatic depot disease ● Radiology of hepatobilier system ● E.Granulozus and Kist Hidatics ● Acute Pancreatitis ● Chronic pancreatit ● Diseases of pancreas ● Tumors of pancreas ● Disease of diaphragma and subdiaphragmatic abscess ● Disease of Bilier system ● Plasmodiums ● The edema at childiren, ascites and hepatomegalia ● Physiophatology of diarrhea ● T. Vaginalis, G. İntestinalis ● The nourtishment desorders ● Mother milk ● Artopodies ● Vitamin deficiency Assessment Methods A clinical and a written exam are performed at the and of the course. Prerequisite/ Recommended None ENDOCRINE SYSTEM and METABOLISM 6 ECTS credits 3rd year-2nd semester Undergraduate Required 33 h/week Lectures: 30 h/week in Turkish Total 3 weeks and 1 day Clinical-integrated practice: 3 h/week Contact: Ramiz Çolak, Nusret Akpolat Aims and Objectives of the Course This course aims to introduce the student with the following items while learning the pathophysiology of diseases on the system basis: 1. Endocrinology and metabolism, evaluation of the pathophysiological findings and clinic events 2. Endocrinology of growth beginning from the childhood 3. Pathopsiology and the pathology of the mammary gland and whole endocrine system in the adult. Course Contens • Childhood: puberty and growth anomalies, endocrine diseases in childhood, anomalies in sexual development
    • • Adulthood: biochemistry of endocrine system, biochemical diagnostic methods and pathophysiology of endocrine system disorders, benign and malignant pathologies. • Pharmacology: drugs related to pituitary and hipothalamic hormones, ostrogenes-progestins- androgenes and their antagonists, antidiabetic drugs, drugs related to calcium metabolism, thyroidal and antithyroidal drugs, corticosteroids. Assessment methods One written exam is scheduled at the end of the whole course Prerequisite/recommended None Texbook/Recommended Reading 1. Braunwald H., Fauci A.S., Kasper D.L., Hauser S.L., Longo D.L., Jameson J.L., “Harrisons’ Principles of Internal Medicine”, 15th edition, McGraw-Hill Professional, (2001) 2. Katzung, B. G., “Basic & Clinical Pharmacology”, McGraw-Hill, (2001) 3. Kumar V., Cotran R.S., Robbins S.L., (Çeviri Ed.: Çevikbaş U.), “Robbin’s Basic Pathology (Temel Patoloji)”, Nobel Tıp Kitapevleri, (2003) 4. Anderson S.C., Cockayne S., “Clinical Chemistry: Concepts and Applications”, McGraw Hill, (2003) UROGENITAL SYSTEM 6.ECTS credits 3rd year- 2nd semester Undergraduate Required Lectures: 88 h/ 3weeks and 1 day Total 3 weeks Clinical, integrated and pathology practice: in Turkish 1 day 13 h / 3weeks and 1 day Contact: İbrahim Hanifi Özercan, Ayhan Doğukan Aims This course aims to teach the students, pathophysiology of diseases, clinical features, diagnosis, tests and evaluation that are helpful to diagnosis of diseases related to urogenital system, male and female genital sistem Course Contents • Female genital sistem; endocrinology and physiology, pathophysology of genital organ disease benign and malignant diseases and their pathological features • Female genital sistem; Pathology of Endometrial hyprplasia and drug therapy • Pregnancy; the physiology of the reproductive functions and pregnancy, pathophysiologic changes pregnancy • Oral contraceptives and induced endometrial changes • Vagen , vulva and cerviks disease and tumors • Non-neoplastic functional ovarian cysts • Ovarian benign and malign tumors • Pathology of urinary system diseases: Structural charasteristics of kidney, pathogenesis of glomerular diseases (primary, secondary), pathogenesis and pathology of acute renal failure,
    • pathology in congenital malformations, pathology in obstructions and tubulointerstitiel diseases • Cystic disease of the kidney • Clinical manifestations histologic alterations pathogenesis of glomerular injury • Diseases affecting tubules and interstitium • Disease of blood vessels of the kidney • Pathology of urinary system tumors, pathology of prostatic diseases, pathology of testicular and epididymal diseases, pathology of penil diseases. • İnflamations and tumors of urinary bladder • Pharmacology related to urinary system: drugs affecting acid-base balance, diuretics, drugs in the treatment of urinary infections. • Biochemistry related to urinary system: Nonproteic nitrogene compounds and biochemical diagnosis in main renal diseases, tests to evaluate renal functions, urinalysis and interpretation, biochemical diagnosis in prostatic diseases. • Clinical microbiology related to urinary system: Flora of genitourinary tract, defence mechanisms and predisposing factors to infections, organisms causing urinary tract infections and microbiological diagnosis, • Urinary system diseases in children: Functions related to renal structural characteristics, role of kidneys in the regulation of extracellular fluid volume and osmolarity, maesurement and evaluation of blood pressure in children, syndromes suggesting renal diseases, symptoms and mechanisms of nephritic syndrome, symptoms and mechanisms of acute renal failure, embryologic malformations and clinical signs, physiology of micturation and developmental disorders, pathogenesis and clinical features of urinary tract infections, diet and treatment in renal failure, renal replacement therapy. • Internal medicine in urinary system diseases: physiopathology of hypervolemia-oedema, asid- base balance/disbalance, potassium metabolism and disorders, calcium-phosphorus metabolism and disorders, symptom and mechanisms of nephritic syndrome, chronic renal failure, relations between blood pressure and kidney, physiopathology of hypertension, incidence and causes of hypertension. • Urologic disorders: symptomatology in urology, vesicoureteral reflux, nonspecific infections of urinary tract, uroepitelial tumors, renal tumors, diseases transmitting sexual intercourse, prostate cancer, benign prostate hyperplasia, testis tumors, voiding dysfunction and urodinamy, defects causing intrascrotal mass,, stone disease of urogenital system. • Neurologic disorders of urinary system: neurologic voiding disorders, impotance. Prerequisite/ Recommended None Textbook/Recommended Reading 1. Strohl W.A., Rouse H., Fisher B.D., “Mikrobiyoloji”, (2001) 2. Scaechter M., Engleberg N.K., Eisenstein B.I., Medoff G., “Mechanism of Microbial Disease”, 3rd edition, Lippincott, Williams & Wilkins, (1998) 3. Cura A., “Çocuk Sağlığı ve Hastalıkları”, Ege Çocuk Vakfı Yayınları No:6, (1999) 4. Barratt M.T., Anver E.D., Harmon E.H., “Pediatric Nephrology”, 4th edition, Lippincott, Williams & Wilkins, (1999) 5. Dorhout Mees E. J., “Böbrek Fizyopatolojisi: Teoriden Uygulamaya”, Ege Üniversitesi Basımevi, (1992) 6. Akpolat T., Utaş C., Süleymanlar G., “Nefroloji El Kitabı”, Nobel Tıp Kitabevi 7. Rose B.D., Post T.W., “Clinical Physiology of Acid Base and Electrolyte Disorders”, McGraw- Hill, (2001) 8. “Temel Üroloji” Güneş Kitabevi (1998) 9. Tellaoğlu S., Kadıoğlu A., Köksal T., “Erkek Seksüel Disfonksiyonu”, Nobel Kitabevi, (2000)
    • 10. Cotran R.S., Kumar V., Robbins S.L., “Robbins’ Pathologic Basis of Disease”, 6th edition, WB Saunders Co., (1999) 11. Anderson S.C., Cockayne S., “Clinical Chemistry: Concepts and Applications”, McGraw Hill, (2003) NEUROPSYCHIATRY 6 ECTS credits 3rd year-2nd Undergraduate Required semester 30 h/week Lectures: 25h/week In Turkish Total 3 weeks Clinical-integrated practice: 5h/week Contact: Hakkı Engın AKSULU, Engın SAHNA Aims and Objectives of the Course This course aims to teach the students the pathophysiology of the disorders of central nervous system(CNS), periferal nerves and sense organs; their clinical features, etiopathogenesis and pathogenesis; the drugs affecting these systems, their therapeutic targets and pharmacological features. Course Contents • Monoaminergic and peptidergic pathways of the CNS and their contributions in the pathopysiological process • Disorders of the motor and extrapyramidal systems • Clinical and pathological changes in CNS tauma • Congenital CNS malformations, hydrocephalus and intracranial pressure • İnfections of CNS • Degenerative, metabolic and toxic disorders and tumors of CNS • Mental and affective disorders of CNS • Convulsive disorders and epilepsy in children and adults • Drug abuse and addiction • Eye, ear-nose and throat diseases • Sedatif-hypnotic, anxiolitic, antidepressant, neuroleptic, anticonvulsant drugs; opioid analgesics, general and local anesthetics, myorelaxants and CNS stimulants and their pharmacology. Assessment Methods One practice exam is performed during the course an done written exam is scheduled at the end of the whole course. Prerequisite/ Recommended None Textbook/Recommented Reading 1. Robbins Basic Pathology ( Temel Patoloji ) Çeviri Ed. Prof. Dr. Uğur ÇEVİKBAŞ, Nobel
    • Tıp Kitapevleri, 2003. 2. Tıbbi Farmakoloji, Ed. Prof. Dr. S. Oğuz KAYAALP, Hacettepe-TAŞ, 2002. 3. Nöroloji Ders Kitabı, Ed. Prof. Dr. Korkut YALTKAYA, Palme Yayıncılık, 2000. 4. Essential Otolaryngology, Baş ve Boyun Cerrahisi, Ed. K.J. Lee, Çeviri Ed. Prof. Dr. Metin ÖNERCİ, Doç. Dr. Hakan KORKMAZ, Güneş Kitapevi, 2004. 5. Klinik Anestezi, Ed. Prof. Dr. Zeynep KAYHAN, Logus Kitapevi, 2004. 6. Temel Psikiyatri, Ed. Prof. Dr. Ertuğrul KÖROĞLU, Prof. Dr. Cengiz GÜLEÇ, Nobel Tıp Kitapevleri, 1997. 7. Pediyatri, Ed. Prof. Dr. Olcay NEYZİ, Prof. Dr. Türkan ERTUĞRUL, Nobel Tıp Kitapevleri, 2002. 8. Temel Nöroşirürji, Çeviren: Prof. Dr. Osman Ekin ÖZCAN, Güneş Kiyapevi, 2000. 9. Parson’s Göz Hastalıkları, Çeviri Ed., Prof. Dr. Hikmet ÖZÇETİN, Atlas Tıp Kitapevi, 1989. 10. İnfeksiyon Hastalıkları ve Mikrobiyolojisi, Ed. Prof. Dr. Ayşe WILLKE TOPÇU, Prof. Dr. Güner SÖYLETİR, Prof. Dr. Mehmet DOĞANAY, Nobel Tıp Kitapevleri, 2002. LOCOMOTOR AND HEMOPOIETIC SYSTEMS 3rd ear- 6 ECTS credits nd Undergraduate Required 2 semester 103 h Lecture: 27 h/week in Turkish Total 3 weeks Clinical-integrated practice: 5 h/week Lectures: Laboratory practices: Pathology Pathology Internal medicine Pharmacology Physical therapy&Rehab. PBL Orthopedic surgery Medical Skills Pediatrics Pharmacology Clinical Biochemistry Dermatology Plastic &Reconst. Surgery Radiology Nuclear medicine Contact: Bilal USTUNDAG, Ayhan KAMANLI Aims and Objectives of the Course The aim of this course is to teach 3rd year medical students the etiology, physiopathology, clinical manifestations, diagnosis, differential diagnosis and treatment of musculoskeletal system and hematopoietic system diseases such as metabolic bone diseases, traumatic bone fracture, osteomyelitis, arthritis,amiloidozis, vertebral diseases, soft tissue tumors, bone tumors, iron deficiency anemia, hemolytic anemia, megaloblastik anemia, Haemoglobinopathy, porfiria, lymphadenopathy, lymphomas, leukemias, hemophilia, thrombocytopenic purpura, and fat soluble and water soluble vitamins and injury due to heat and cold.
    • Course Contents • Metabolic bone diseases traumatic bone fracture, osteomyelitis, aseptic bone necrosis, arthritis, vertebral colon diseases, familial meditereanean fever amiliodozis: etiology, physiopathology, clinical manifestations, radiologic findings, biochemical features and drugs used for treatment. • Soft tissue and bone tumors: physiopathology, clinical manifestations, radiologic findings and anticancer treatment. • Anemia, Iron deficiency anemia, hemolytic anemia, megaloblastic anemia and haemoglobinopathy: physiopathology, clinical manifestations, laboratory findings and drugs used for treatment of hemophilic anemia observed in adults and children. • Lymphadenopathies, lymphomas, leukemias: physiopathology, diagnosis, differential diagnosis of lymphadenopathies, leukemias and malign lymphomas observed in adults and children, anti-cancer treatment used in hematologic malignancies. • Hemophilia, thrombocytopenic purpura and thrombosis: Physiopathology, clinical manifestations, differential diagnosis of hemophilia and purpura observed in adults and children, anticoagulant and antithrombotic therapy. • Vitamins, clinical manifestations, laboratory findings of avitaminosiz and hypervitaminozis of water soluble and fat soluble vitamins, • Treatment and clinical manifestations injury due to heat and cold, treatment of primary injury, Integrated sessions Hodgkin Lymphoma are discussed in a panel, to review the overall course contents. Assesment Methods A clinical practice exam and a final written exam at the end of course are scheduled. Textbook / Recommended Reading 1-Kumar V., Cotran R.S., Robbins S.L., (Çeviri Ed.: Çevikbaş U.), “Robbins Basic Pathology (Temel Patoloji)”, Nobel Tıp Kitapevleri, (2003) 2-Gümüşdiş G., Doğanavşargil E., “ Klinik Romatoloji”, Deniz Matbaası, (1999) 3-Physical Medicine and Rehabilitation Editors: Braddom RL. WB Sounders Company Philadelphia (2000)- 4- Oxford Textbook of Rheumatology . Maddison PJ et al.Oxford University pres (1998) 5-Kayaalp S.O., “Rasyonel Tedavi Yönünden Tıbbi Farmakoloji”, Hacettepe-Taş Kitapçılık, (2000) 6-Rang H.P., Dale M.M., Ritter J.M, “Pharmacology”, Churchill Livingstone, (1999) 7-Burtis C.A., Ashwood E.R., “Tietz Textbook of Clinical Chemistry”, WB Saunders Company, (1999)
    • 8-Kaplan L.A., Pesce A.J., Kazmierczak S.C., “Clinical Chemistry: Theory, Analysis and Correlation”, Mosby, (2003) 9-Yücetürk G., “Ortopedi ve Travmatoloji”, Saray Medikal Yayıncılık, (1997) 10-Lilleyman J., Hann I., Blanchete V., “Pediatric Hematology”, Churchill Livingstone, Harcourt Brace & Company, (1999) 11-Lanzkowsky P., “Manual of Pediatric Hematology and Oncology”, Academic Press, (1999 ). 12-Beutler E., Lichtman M.A., Coller B.S., Kipps T.J., “Williams Hematology”, The McGraw Hill Companies, (2001) PUBLIC HEALTH AND MEDİCAL ETHICS 6 ECTS credits 3rd year-2nd semester Undergraduate Required 30 h/week In Turkish Total 2 weeks and 4 Lectures: 30 h/week days (80 hours) Contact: Yasemin Acik, A.Ferdane Oguzoncul, S.Erhan Deveci, A.Tevfik Ozan Aims and Objective of the course Objective of public health is to ensure that the society and its members are healthy in terms of physical, mental, social and environmental aspects. For this purpose, the responsibilities assumed by the Department of Public Health is to determine the health status of the public, the existing and potential problems, causes of these problems and the health-related needs of the society by using scientific methods; to develop public health policies and to produce solutions; to conduct inspections and evaluations on the public health programs, to ensure the implementation of these programs and to manage every level of health services. In this framework, the objectives of this course committee are as follows: • To provide an integrated approach towards health and to ensure that basic health services are considered as a dimension of the health services. • To raise consciousness about the importance of preventive health services in the provision of health services. • To discuss the process of health services provision, organization and health staff. • To discuss topics of Health Education, Health Management, Health Systems, Health Economics and to evaluate criteria of health level. • To discuss the importance of epidemiology and scientific studies. • To discuss the significance of nutrition and healthy and balanced nutrition in terms of public health. • To comprehend the way the environment a person lives affect his /her health and to discuss concerned measures that should be taken. • To enlighten how workplace conditions affect the health of person and to discuss social problems. • To discuss health problems and social problems of certain age groups. • To ensure that the significance of public health and the provision of health services are understood well.
    • • To comprehend the importance of public health and health services in extra-ordinary conditions. • To discuss the problem of cigarette and other addictive substances in Turkey and in the world on the public and its effects on the public health. Course contents Introduction to public health Health organization in Turkey Primary health care Health-related Objectives for 21th century Health Level Criteria and the Situation in the Country Growth monitoring Breastfeeding and Problems Concerning Breastfeeding Nutrition in the First 5 Years Food safety and nutrition Food deficiency disease Health education and communication Children’s Health Research planning and ethics Bio-statistics Occupational safety and health Occupational health and ethics Occupational disease Adolescence and School Health Health matters of elderly Epidemiology and prevention of infections Diseases Epidemiology and prevention of Chronic Diseases Tobacco and the other substance use and control Epidemiology Reptoductive right and health Family planning Safe Motherhood Safe sexual lifetime Sexually Transmitted disease Mother and child health status in Turkey Risk approach to mother and child health Childhood enfection disease Immunization Primary health services and environmental health Health management and history Health Systems and Economics Health impact of the disasters Cemical, biological and nuclear weopons and prevention Computer use in public health Epidemiology of Mental health and disease Public health Medicine opinion about accident The patient right and ethics The physicians right and ethics Spesific topics in public health Assesment Methods A written exam is scheduled at the end of the course. Prerequsite/recommended None Textbook/Recommended reading
    • 1. Fişek NT. Halk Sağlığına Giriş. Çağ Matbaası, 1985. 2. Tezcan S, Epidemiyoloji. Hacettepe Halk Sağlığı Vakfı. Yayın No: 92/1. Ankara, 1992. 3. Dirican R, Bilgel N. Halk Sağlığı (Toplum Hekimliği). Uludağ Üniversitesi Basımevi, 1993. 4. Bertan M, Güler Ç. Halk Sağlığı (Temel Bilgiler). Güneş Kitabevi, Ankara, 1995. 5. Concerned we sites: (www.die.gov.tr), (www.saglik.gov.tr), (www.who.int), (www.cdc.gov), (www.ilo.org), (www.tttb.org), (www.cevre.org), (www.unicef.org).