BIO 419 Immunology

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BIO 419 Immunology

  1. 1. William Carey College Department of Biological Sciences BIO 419: Immunology Course Syllabus Summer Trimester 2006 Dr. Randall Harris Room 121, Green Science Hall Phones: Office 601-318-6595; Home 601-583-0977; Cell 601-329-6143; Fax 601-318-6414 E-mail: randall.harris@wmcarey.edu Class Website: http://groups.yahoo.com/group/bio419_summer2006/ Class E-mail: bio419_summer2006@yahoogroups.com Office hours: During the summer I do not keep set office hours; please call or email me to make an appointment if you need to speak with me in person. Textbook Immunology, A Short Course, 5th edition – Coico, Sunshine, and Benjamini Wiley-Liss Publishers Catalog description (4 hours) A study of the principles of acquired and natural immunity with references to antigens, antibodies, immune response, complement, and susceptibility. The concepts of mediated immunities and immunopathology are also considered. A one semester hour laboratory experience is included. Prerequisite: BIO 235, 260 Course description This course serves as a foundational immunology course for all biology majors and minors. Students will acquire a basic understanding of the current state of our knowledge of the immune system 25 years after the beginning of the AIDS epidemic. Course objectives Upon completing the requirements of this course the student will be able to: a. outline the basic components of the vertebrate immune system; b. understand the molecular processes behind the humoral and cellular immune responses; c. understand the nature of soluble mediators of the immune system; d. compare and contrast the aspects of innate and acquired immunity. Teaching methods The teaching methods used to achieve the goals and objectives of the course include lecture, discussion, demonstration, small group activities, application problems, and hands-on experimentation with immunology techniques and procedures. Course requirements and policies 1. Attendance You are expected to attend every class and lab meeting. “Getting someone else’s notes” cannot substitute for the experience of being in class, hearing the discussion of the topic and being able to ask timely questions. Furthermore, in accordance with official college policy, if you miss five
  2. 2. of the scheduled class meetings (25% of 20 meetings), you will fail the course automatically. An absence will be classified as “excused” if you have documentation of the following: a. personal medical situation b. death in the immediate family c. college-sponsored event d. other circumstances of which I am notified appropriately in advance if possible Please note that an excused absence from class does not relieve you of any obligations in terms of coursework. 2. Grading scale The grading scale for the course is a 10-point scale (90-100 A; 80-89 B; etc.) 3. Evaluation 4 exams (including Final) = 70% of total grade Presentation of an immune disease = 15% of total grade Lab Reports = 15% of total grade 4. Drop grade Students will be allowed to drop their lowest exam grade IF they have missed no more than two class meetings. It does not matter if the absences are excused or unexcused. If the attendance requirement has been met, and the grade on the final exam will not change the final average, then the final exam may be used as the drop grade and the student will be exempt from the final. 5. Exam format Examinations may be a combination of multiple choice, matching, true/false, short answer (a question that can be answered by a few phrases or sentences), discussion questions (extended answers), or application/problem-solving questions. The focus of exams in this class will be the synthesis and application of concepts. To this end, you should make sure that you completely understand concepts as we go along. Do not hesitate to ask me for help! 6. Make-up work and exams a. Only students with excused absences may make up assignments or exams. b. Exams must be made up within one week after the exam was originally given; after this period of time, the student will receive a zero on the exam. 7. Presentation Each student will give a 10-minute presentation on an immune disorder assigned by the professor. These presentations will be lecture-style, and the material presented in them will be eligible for testing on the final exam. Rules, guidelines, and a grading rubric will be issued. 8. Americans with Disabilities Act Students with disabilities who are protected by the Americans with Disabilities Act of 1990 and require special accommodations, should contact Mrs. Brenda Waldrip at 601-318-6188. Mrs. Waldrip is located in the Student Services Office in Lawrence Hall. 9. Academic integrity William Carey College seeks to create an environment that encourages continued growth of moral and ethical values, which include personal honesty and mutual trust. The college places the highest value on academic integrity and regards any act of academic dishonesty as a serious
  3. 3. offense. Academic dishonesty is considered unethical and in violation of William Carey College’s academic standards and Christian commitment. If such an incident occurs, students, faculty, and/or staff are obligated to initiate appropriate action. Depending upon the seriousness of the offense, sanctions could include failure of the assignment, failure of the course, and could lead to suspension or dismissal from the college. A full explanation of the procedures for responding to instances of academic dishonesty are contained in the college’s Policies and Procedures manual and in the student handbook, The Lance. In this class, if you are caught engaging in an act of academic dishonesty (cheating on an exam by looking on another person’s paper or using notes during the test; plagiarism in written work; etc.), you will fail the course. 10. Technology From time to time, coursework may involve the use of information that is gathered from the WWW. (Internet access is available in the college library.) Email is highly recommended as the most efficient way to communicate with me. Course documents and other communications will be supplied via a Yahoo Group (see URL on the first page of this syllabus). 11. Academic schedule It is imperative that you make note of the following dates in the academic calendar: Friday, June 16: Last day to drop a class with a grade of W Friday, June 30: Last day to drop a class with a grade of WP or WF If you find that you have gotten in over your head, I strongly encourage you to drop the class as soon as possible. A grade of “I” (Incomplete) will not be given to a student who should have dropped the course. (Please see the college’s policy on incompletes, next section.) 12. College policy on incompletes A grade of “I” (incomplete) will be assigned only when unavoidable circumstances prevent completion of the work of the course on schedule and must be approved by the instructor and the academic dean. Requests are made using the Incomplete Grade Request form obtained from the registrar’s office. The following criteria must be met before an incomplete request will be considered: a. semester attendance requirements have been met; b. most (80%) of the required work for the class has been done; c. the student is doing passing work; d. the student has requested the grade of incomplete on the proper form prior to the time when faculty must submit the term’s grades to the registrar (noon on the last day of exam week); e. the appropriate documentation has been provided by the student regarding the reason for requesting the incomplete; the documentation will vary according to the reason. Course Schedule Date Assignment/Reading/Lecture May 29 (M) Introduction to the Course; Chapter 1: Introduction and Overview June 1 (R) Chapter 2: Elements of Innate and Acquired Immunity June 5 (M) Exam 1 (Chapters 1 and 2) June 8 (R) No meeting
  4. 4. June 12 (M) Chapter 3: Immunogens and Antigens June 15 (R) Chapter 4: Antibody Structure and Function June 19 (M) Chapter 6: The Genetic Basis of Antibody Structure June 22 (R) Exam 2 (Chapters 3, 4, 6) June 26 (M) Chapter 7: Biology of the B Lymphocyte June 29 (R) Chapter 8: Biology of the T Lymphocyte July 3 (M) Chapter 9: The Role of MHC in the Immune Response July 6 (R) Chapter 10: Activation and Function of T and B Cells July 10 (M) Chapter 11: Cytokines July 13 (R) Exam 3 (Chapters 7, 8, 9, 10, 11) July 17 (M) Chapter 13: Complement July 20 (R) Chapter 14: Type I Hypersensitivity July 24 (M) Chapter 15: Types II and III Hypersensitivity July 27 (R) Chapter 16: Type IV Hypersensitivity July 31 (M) Presentations August 3 (R) Final Exam (Chapters 13, 14, 15, 16) Course References Professional Journals Cell Infection and Immunity Journal of Immunology Nature Proceedings of the National Academy of Sciences Science Selected World Wide Web Sites Microbiology and Immunology Online. http://pathmicro.med.sc.edu/book/immunol- sta.htm The Biology Project: Microbiology and Immunology. http://www.biology.arizona.edu/ immunology/immunology.html Biology Links: Immunology. http://mcb.harvard.edu/BioLinks/Immunology.html Immunology Animations (Davidson College) http://www.bio.davidson.edu/ courses/Immunology/Bio307.html

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