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Applying for a Grant at the NIH
 

Applying for a Grant at the NIH

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    Applying for a Grant at the NIH Applying for a Grant at the NIH Presentation Transcript

    • Applying for a Grant at the NIH Helen Quill, Ph.D. Chief, Basic Immunology Branch Division of Allergy, Immunology & Transplantation NIAID, NIH
    • The Application Process
    •  
    • 2 Independent Assignments for Your Grant Application upon Receipt at NIH
    •  
    • Peer Review “ Before you criticize someone, you should walk a mile in their shoes. That way when you criticize them, you’re a mile away and you have their shoes.” -Steven Wright
    • CSR (Center for Scientific Review)
      • Study Section
      • peer review panel
      • 15-25 reviewers, mostly from academia
      • IRG (integrated review group)
      • group of study sections
    • New Immunology IRG
      • New Study Sections: est. June 2004
      • Innate Immunity & Inflammation (III)
      • Immunity & Host Defense (IHD)
      • Cellular & Molecular Immunology (CMI)-A
      • Cellular & Molecular Immunology (CMI)-B
      • Hypersensitivity, Autoimmune & Immune-Med. Dis. (HAI)
      • Transplantation, Tolerance & Tumor Immunology (TTT)
      • Vaccines Against Microbial Diseases (VMD)
      • F32 Postdoctoral Grants
    •  
    • Institute Program Officer
      • Designated Federal official with overall
      • responsibility for the funding process
      • Scientist trained in area of coverage
      • Develops targeted research programs
      • Approves funding and oversees funded grants
      • Approves yearly progress reports
      • Assists PI with both administrative & scientific questions
      • Attends study section as observer
    •  
    • Review Process
      • 6-8 wks before study section meeting
      • SRA assigns and sends applications to primary, secondary, tertiary reviewers (mostly academics) for evaluation
      • At study section meeting
      • - These 3 reviewers give initial scores
      • - Primary presents research plan, discusses PI, etc.
      • - Secondary emphasizes points of agreement/disagreement
      • - Tertiary adds his/her 2 cents worth
      • - General discussion/questions among panel members
      • - All panel members vote a priority score
      • Less expected from new PI
    • Review Process
      • 1-2 months after review
      • - SRA prepares summary statement (written critique document) and calculates percentiles (R01s)
      • - CSR or Institute mails summary statement to PI
      • ~ 5 months after review
      • Institute sends Notice-of-Grant Award by e-mail to PI’s business office
    • Paylines
      • Payline is based on percentile (rank)
      • Percentile: your score percentiled against current scores in that study section plus the previous 2 rounds of review in that study section
      • Each Institute determines its own payline (e.g. in 2003, NIAID 22.0%; NCI 20.0%)
      • Payline may be different from prior fiscal year
      • For most Institutes, percentiles within the payline get funded automatically
      • Study sections may recommend budget/time cuts; Institutes usually follow these recommendations
    •  
    • Funding Mechanisms
    •  
    • K08 Mentored Clinical Scientist Development Award
      • Clinical doctoral degree only
      • US citizenship or green card
      • 3-5 yrs of support
      • Salary: up to $75K + FB/yr
      • Supplies: up to $20K/yr
      • 75% effort required
    • K23 Mentored Patient-Oriented Research Career Development Award
      • M.D. or Ph.D. working with patients
      • US citizen or green card
      • Candidates just out of specialty or sub-specialty training
      • Project must be patient-oriented research
      • 3-5 yrs of support
      • Salary: up to $75K + FB/yr
      • Supplies: $25K/yr
      • 75% effort required
    • K22 Research Scholar Development Award
      • Postdoc moving to assistant professor
      • Eligibility
        • Current NIAID intramural postdoc
        • Current postdoc on NIAID training grant/fellowship
        • US citizen or green card
      • 2 yrs non-renewable
      • Yr 1: $150K; yr 2: $100K
      • Can apply without a sponsoring institution
    • SUCCESS RATES FOR NIAID TRAINING AND CAREER DEVELOPMENT GRANTS
      • Grant Type
      • F32
      • K02
      • K08
      • K22
      • K23
      • K24
      • T32
      • OVERALL
      • 2002 Success Rate (%)
      • 25
      • 63
      • 66
      • 59
      • 39
      • 27
      • 60
      • 43
    •  
    • R01 Success Rates (%) All PIs 30.9 27.2 27.2 30.2 32.8 NIDDK 32.0 34.4 33.3 34.6 30.7 NHLBI 25.9 26.0 26.9 29.8 30.2 NCI 30.8 34.2 30.8 30.9 35.5 NIAID N/A 31.3 31.4 31.6 30.9 NIH 2002 2001 2000 1999 1998
    • R01 Success Rates (%) New PIs NIH-wide 22.0 23.0 23.7 22.9 23.8 Success rate 1,596 1,640 1,670 1,596 1,539 Grants awarded 7,265 7,139 7,059 6,984 6,464 Applications reviewed 2002 2001 2000 1999 1998
    • Solicited Research Programs NIH Institutes
    •  
    •  
    •  
    •  
    • Help
    • How NIH Staff Can Help You
      • CSR Scientific Review Administrator (SRA)
      • Before review
      • Advice on study section, amount of preliminary data, supplementary data, etc.
    • How NIH Staff Can Help You
      • Institute Program Officer
      • Before review
      • Scientific advice on proposed Aims; on revised Aims; on study section, etc.
      • After review
        • Discuss review, summary statement, revision
        • Provide information on payline, funding status
        • Rarely – help with funding outside the payline
    • How NIH Staff Can Help You
      • Use the Institute Program Officer
      • as your point person at NIH
    •  
    • Spend some time at the NIH and NIAID websites!
    • Websites
      • NIH Home Page: www.nih.gov
      • Training/Career Development: www.training.nih.gov
      • Grant Guidelines/Forms:
      • www.nih.gov/grants/documentindex.htm
      • How to Write a Grant:
      • www.niaid.nih.gov/ncn/grants/write/index.htm
      • NIH Guide:
      • http://grants.nih.gov/grants/guide/index.html
      • NIAID Solicited Biodefense Research Programs:
      • www.niaid.nih.gov/biodefense
    • New Immunology IRG
      • New Study Sections: est. June 2004
      • Innate Immunity & Inflammation (III)
      • Immunity & Host Defense (IHD)
      • Cellular & Molecular Immunology (CMI)-A
      • Cellular & Molecular Immunology (CMI)-B
      • Hypersensitivity, Autoimmune & Immune-Mediated Diseases (HAI)
      • Transplantation, Tolerance & Tumor Immunology (TTT)
      • Vaccines Against Microbial Diseases (VMD)
      • F32 Postdoctoral Grants