Arteriosclerosis - Homoeopathic & miasmatic view


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Arteriosclerosis - Homoeopathic & miasmatic view

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  • Once the inner wall of an artery is damaged, blood cells called platelets often clump at the injury site to try to repair the artery, leading to inflammation. Over time, fatty deposits (plaques) made of cholesterol and other cellular waste products also accumulate at the injury and harden, narrowing your arteries. The organs and tissues connected to the blocked arteries then don't receive enough blood to function properly.Eventually pieces of the fatty deposits may rupture and enter your bloodstream. This can cause a blood clot to form and damage your organs, such as in a heart attack. A blood clot can also travel to other parts of your body and partially or totally block blood flow to another organ.
  • Following injury to endothelium, there is accumulation of LDL. Following by oxidation of LDL. There is adhesion & migration of blood monocytes, transforation to macrophages.Adhesion of plateles.Relaease of cytokines and other factors from platelets and macrophages.
  • Atheroma of arteries (arteriosclerosis) – Adren., Am. iod., Am. vanad., Ant. ars., Arn., Ars., Ars. iod., Aur. iod., Aur., Aur. m. n., Bar. c., Bar. m., Cact., Calc. fl., Chin. s., Con., Crat., Ergotin, Glon., Iodothyr., Kali iod., Kali sal., Lach., Lith. c., Nat. iod., Phos., Plumb. iod., Plumb. m., Polygon. av., Sec., Stront. c., Stront. iod., Stroph., Sumb., Vanad.CORONARY ARTERY DISEASE (Acute insufficiency of the left ventricle leading to pulmonary edema) (11) : am-c., ant-t., apis, ars., carb-v., dig., kali-c., lach., nat-m., phos., sulph.Tissue remediesArteriosclerosis66 Natriumphosphoricum, Silicea terra, NatriumsulphuricumHigh blood pressure due to arteriosclerosis67Calcareaflourica, Ferrumphosphoricum
  • Baryta Mur – hypertension and vascular degeneration; arteriosclerosis where high systolic pressure with a comparatively low diastolic tension is attended by cerebral and cardiac symptoms;  large blood vessel and aorta is involved; in duration and narrowing of cardiac orifice with  pain immediately after eating
  • Arteriosclerosis - Homoeopathic & miasmatic view

    1. 1. Dr. Manshi Mankiwala M.Sc. Public Health, M.D. Homeopath
    2. 2.  Atherosclerosis is a specific type of arteriosclerosis, but the terms are often used interchangeably.  Atherosclerosis refers to the build up of fats in and on your artery walls (plaques), which can restrict blood flow.  These plaques can also burst, causing a blood clot. Although atherosclerosis is often considered a heart problem, it can affect arteries anywhere in your body. Atherosclerosis is a preventable and treatable condition.
    3. 3.  Arteriosclerosis obliterans is typically seen in medium and large arteries of the lower extremity. Characterized by fibrosis of the intima and calcification of the media. The lumen of the vessel may be obliterated or markedly narrowed.  Medial calcific sclerosis (Monckeberg’s calcific sclerosis) is seen mostly in the elderly, commonly in arteries of the extremities. Characterized by calcification of the Tunica media but without thickening of the intima or narrowing of the vessel lumen.  A similar form of an intramural calcification, presenting the picture of an early phase of arteriosclerosis, appears to be induced by a number of drugs that have an antiproliferative mechanism of action
    4. 4. Major Components of Plaque  Cells (Macrophages & other WBCs)  Collagen, elastin  Lipid ( Intra / extra cellular Cholesterol)  Often Calcification Major Processes in Plaque  Intimal Thickening (proliferation of smooth muscles and elastin & collagen formation)  Lipid accumulation
    5. 5.  Injury to the endothelium ( dysfunctional endothelium)  Chronic inflammatory changes  Migration of smooth muscle cells from media & intima  Proliferation of smooth muscle cell in intima  Increased production of elastin, collagen  Enhanced lipid accumulation
    6. 6. Consequences
    7. 7. Carotid & Cerebral Circulation  Brain infarction  TIA if arterial narrowing is aggravated by mural vasospasm Celiary & Mesentric Arterial circulation  Ischemic entricolitis  Nephrosclerosis leads to gradual renal failure  Renal hypertension  Iliac or femoral artery aneurysms  Vessel occlusion by plaque / thrombus, which can lead to ulceration / gangrene of the part
    8. 8. Coronary Artery Disease  Symptoms of coronary artery disease (where the heart arteries are narrowed) are usually brought on by physical exercise, exposure to cold weather, anger, or stress. The most common symptoms include:  Chest pain (generally a heavy, squeezing, or crushing sensation with possible burning or stabbing pains)  Abdominal, neck, back, jaw, or shoulder/arm pain  Weakness  Perspiration  Shortness of breath 
    9. 9. Cerebrovascular Disease  Cerebrovascular disease (where the arteries that supply the brain with blood) are narrowed can cause transient ischemic attack (a sudden loss of brain function with complete recovery within 24 hours) and stroke.  Symptoms may include:  Weakness or paralysis on one side of the body  Trouble speaking or understanding speech  Loss of vision in one eye  Muscle weakness  Difficultty in walking  Dizziness  Loss of balance or coordination  Sudden severe headache
    10. 10. Peripheral Artery Disease  Peripheral artery disease affects the arteries that supply the arms and legs with oxygen rich blood. Symptoms may include:  Pain, aching, cramps, numbness or sense of fatigue in the leg muscles (intermittent claudication)  "Bruits" (blowing sounds can hear with a stethoscope that indicate turbulence in blood flow)  Thickened nails  Smooth, shiny skin surface  Skin that is cold to the touch  Gangrene
    11. 11.  Menstrual irregularity with premenstrual water retention and swelling of breasts.  High uric acid, high cholesterol, alterration of lipid metabolism leading to deposits of cholesterol and lipoproteins on blood vessel walls.  Hypertension that results from damage to the vascular bed of the kidneys and salt and water retention.  Rheumatoid arthritis with abnormal globulin processes also fall into this category.  Abnormal growth of hair, generalized as well as local.  Stone formation and deposition of calcium in normal tissues.  all expressions of Gouty-Rheumatic Constitutions.  All these tend to be worse in cold damp weather and by rest.  Gouty conditions, worse with over-indulgence in food and wine.  Pain in the insertions of long tendons, muscular aches and pains, recurrent fibrositis in large muscles
    12. 12.  The physical responses in sycosis are erratic, wandering, Metastatic of inflammatory processes.  Hardening of elastic lamina and intimal proliferation.  Atheroma developed in large arteries results in narrowing of lumen and stenosis  Increased peripheral resistance resulting from thickness of walls of the arteries  The sycotic patients are fleshy and puffy, their obesity contributing to complaint of dyspnoea.  Pains in electric shocks, radiates from precordium to the shoulder scapula. soreness or tenderness over precordial region.  Heat and change of waether<;  > from gentle exercise, exept of rheumatic origin.  Pulse is slow, feeble and soft.  Cardiac dropsy, tachycardia, thrombosis, embolism, MI
    13. 13.  aberrant, allergic, hypertrophic, spasmodic responses.  tuberculosis exists in the family history or in the patient’s own history.  Profuse perspiration with musty odour  Emaciation with ravenous appetite  Diabetic syndrome  Cracks and fissures of the skin  Premature greying of hair  chronic inflammation of the skin, mucous membranes, serous membranes, subcutaneous tissues, lungs etc.  protracted recovery  Easy suppuration and delayed healing
    14. 14.  Joint get easily sprained.  Cramps in lower extremities.  Aggravation: Night, from thunderstorm, closed room, morning  Amelioration: quiet , rest, warmth, dry weather, open air  Stress or suppression of emotions
    15. 15.  History or evidence of clinical syphilis  Repeated abortions or miscarriages, still births, neonatal deaths, foetal malformations, placenta praevia, vesicular mole, toxaemia of pregnancy  Cancer  Ectopic tissues (ectopic gestation, mammae, thyroid, uterine endometrium)  Maniac psychosis, psychopathic personalities, criminal propensities, moral depravity, etc.  <night Cracks, fissures, ulcerations with indurations Alopecia  Dental caries before teeth erupt;  bone and peri-osteal pain at night, relieved by cold applications and movement  Osteoporosis leading to fractures and deformities  Ulcerations healing to fibrosis, scarring, and
    16. 16.  Paralysis, occurring as a result of ischaemia, metabolic degenerative states.  Loss of intellectual function, loss of memory, inability to think, comprehend, or learn (Alzheimer’s disease); cerebrovascular accidents where there is degeneration of brain tissue.  Sensation of heaviness in precordium. Symptoms are < at night, perspiration, warmth of bed. > during day, change of possition and cold.  Pulse irregular in rate or rythem.
    17. 17. CRATAEGUS  . Acts on muscle of heart, and IS A HEART TONIC.  No influence on the endocardium. Myocarditis.  Failing compensation. .Insomnia of aortic sufferers,  anaemia; oedema, cutaneous chilliness. High blood pressure.  Is a sedative in cross, irritable patients  with cardiac symptoms. Chronic heart disease,  with extreme weakness. Very feeble and irregular heart action.  Dyspepsia and nervous prostration, with heart failure.  In the beginning of heart disease after rheumatism.  ARTERIOSCLEROSIS. CARDIAC DROPSY. Aortic disease.  Extreme dyspnoea on least exertion without much increase of pulse.  Pain in region of heart and under left clavicle. Dilated heart. .  Pulse accelerated,. Valvular murmurs, angina pectoris.  Cutaneous chilliness, blueness of fingers and toes; all aggravated  by exertion or excitement. Sustains heart in infectious diseases.
    18. 18. AURUM MET  Sensation as if HEART STOPPED BEATING for two or three seconds, immediately followed by a tumultuous rebound, with sinking at the epigastrium.,  Pulse RAPID,FEEBLE,IRREGULAR, Palpitation.  Hypertrophy.  HIGH BLOOD PRESSURE,_Valvular lesions of arteriosclerotic nature.
    19. 19. CACTUS  ENDOCARDITIS WITH MITRAL REGURGITATION together with violent action  Acts best in the incipiency of cardiac incompetence.  Heart weakness of arteriosclerosis.  Violent palpitation; WORSE LYING ON LEFT SIDE, AT APPROACH OF MENSES.  ANGINA PECTORIS, with suffocation, cold sweat, and constriction as if heart were squeezed by an iron hand.  Pain in apex, shooting down left arm. Palpitation, with vertigo, dyspnoea, flatulence.  CONSTRICTION; very acute pains and stitches in heart; pulse feeble, irregular, quick, without strength.  Endocardial murmurs, excessive impulse, increased praecordial dullness, enlarged ventricle. Low blood pressure.
    20. 20. STROPHANTHUS HISPIDUS  Common name – Kombe seed  Part used – Seed  Acts on the Heart increasing the systole and diminishing the rapidity.  A muscle poison , Increases the contractile power of striped muscles.  Heart’s action weak, irregular due to muscular debility and insufficiency. Irritable heart of tobacco smokers.  In mitral regurgitation where oedema and dropsy have supervened.  Arteriosclerosis of the aged.  Nausea without actual vomiting, great loathing of food. Anaemia.  Nausea with disgust for alcohol, aids in treatment of dipsomania.
    21. 21. Baryta muriatica  This drug produces lesions of arteriosclerosis of the large blood vessels and aorta, similar to senile atheroma.  It has the headache with heaviness, worse at night when lying down.  Dizziness of old people. Apoplexy or threatened apoplexy, with buzzing in the ears.  It can be given for a long pulmonary arterio- sclerosis.  hypertension and vascular degeneration; arteriosclerosis where high systolic pressure with a comparatively low diastolic tension is attended by cerebral and cardiac symptoms; large blood vessel and aorta is involved; in duration and narrowing of cardiac orifice with pain immediately after eating
    22. 22. Arnica [Arn]  This is a remedy of value in cerebral arteriosclerosis,vertigo of the aged, heaviness and cerebral affections, plethoric people who have a tendency to haemorrhages.  cerebral arteriosclerosis; great tendency for hemorrhage; acts well in plethoric, feebly in debilitated people, relaxed bold vessel with black and blue spots; sore, lame and bruised feeling; thrombosis; limbs and body aches as if beaten
    23. 23. Plumbum [Plumb]  Hypertension and arterio-sclerosis.  It seems to suit rather the pre- sclerotic states than those of actual sclerosis.  It has a cramp like constriction of the peripheral arteries, a wiry pulse, and especially if the symptoms be associated with a chronic nephritis it is all the more indicated.  Patient feels the pulse in the fingers. Slight motion causes fainting.  It suits the anaemic, pale, emaciated patients with extreme weakness which is the plumbum constitution.
    24. 24. Ergotin –  acts well in the beginning of arteriosclerosis when only the cardiac irritation and the hard heart sound are present.  Stiffening and degeneration of arterial walls, spasmodic contraction of the vessels with hardening Spigelia  remarkable remedy for the inflammation of the heart affecting both inner and outer lining of the heart, deficiency of the mitral valve in people who are alcoholic, pain in the heart, dizziness, noises in head, excessive nervousness, chocking sensation in throat; patient is unable to sleep properly; sparks before the eyes is a guiding symptom of this remedy.
    25. 25. Arsenic iod –  remedy for arteriosclerosis; myocardial degeneration and senile heart; cardiac weakness; emaciation and general debility; best suited to anemic people; rapid, irritable pulse; chronic aortitis. Adrenaline –  high arterial blood pressure; roaring in the ear due to hypertension; its chief therapeutic use depends o its vaso constriction action. Aurum mur –  arterio-sclerosis; high blood pressure due to disturbed function of nervous mechanism; hypertrophy of the heart; congestion in the chest and head; strong palpitation.
    26. 26. Preventive Care:  Stop smoking.  Exercise at least 30 minutes a day, 6 days a week.  Eat healthy foods, such as fruits, vegetables, and whole grains that are low in saturated fat and high in fiber.  Maintain a normal weight (or lose weight if you need to).  Reduce stress.