+Egyptian drug guide_3rd_edition_

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+Egyptian drug guide_3rd_edition_

  1. 1. Abimol.Afrin.Betaserc.Daflon.Concor.Epilat.Trio.Epilat.Adalat.Effox.Indral.Maaloxplus.Lipitor.Zolam,Rivo,D.D.BPanadol.Extra..visineAntiv.VitBBetolvex.Amaryl.Blokium.Ator.Cidrophage. Egyptian Drug GuideAvandia.Cardura.Cozaar.DiaBetolvex. 3rd Edition 2011Daflon.Hyzaar.Migranil.Reparil.Panad Department of Pharmacy Practice and Clinical Pharmacyol.Mylogin.Voltarin.Telfast.Septriun.Solocortef.Viagra.Tenedene.Tequin.Claritine.Epilat.Adalat.Effox.Indral.Maaloxplus.Lipitor.Tavanic.Proximol.Solucortef.Visceralgine.Zocor.Tenedone.Clarinase.Dolphen.Novalgin.Colona.Duxil.Eucarbon.Excedrin.Flagyl.Feldene.Dinitra.Anafranil.Comtrex.Librax.Lipostat.Neurobion.Predforte.avandemet.Avendia.Avendemet.Abilaxine.Concor.
  2. 2. Department of Pharmacy Practice and Clinical PharmacyTable of ContentsDRUGS FOR NEUROLOGIC DISORDERS .................................................................................................................. 5 PAIN MANAGEMENT........................................................................................................................................... 5ANALGESIC, ANTI-INFLAMMATORY AND ANTI- PYRETIC DRUGS ............................................................................................. 5ANALGESIC AND ANTIPYRETICS ...................................................................................................................................... 7OPIOID ANALGESICS .................................................................................................................................................... 7MIGRAINE DRUGS ...................................................................................................................................................... 8SKELETAL MUSCLE RELAXANTS ...................................................................................................................................... 8 ANTI-CONVULSANTS ........................................................................................................................................... 9 ANTI-PARKINSON’S DRUGS ................................................................................................................................ 10 BRAIN DISORDERS ............................................................................................................................................ 10DRUGS FOR PSYCHIATRIC DISORDERS ................................................................................................................. 11 SEDATIVES & ANXIOLYTICS DRUGS ....................................................................................................................... 11 ALZHEIMER’S DISEASE DRUGS ............................................................................................................................. 12 ANTI-DEPRESSANTS........................................................................................................................................... 12 ANTI-PSYCHOTICS .......................................................................................................................................... 13DRUGS FOR CARDIOVASCULAR DISORDERS ........................................................................................................ 14 ANTICOAGULANTS ............................................................................................................................................ 14ANTIPLATELETS ....................................................................................................................................................... 15 CAPILLARY STABILIZING DRUGS ............................................................................................................................ 15 ANTI-ARRHYTHMIC DRUGS ................................................................................................................................. 16 ANTI-ANGINA DRUGS ........................................................................................................................................ 16 ANTI-HYPOTENSIVES ......................................................................................................................................... 17 ANTI-HYPERTENSIVES........................................................................................................................................ 18 LIPID REGULATORY AGENTS ................................................................................................................................ 24RESPIRATORY DISORDERS ................................................................................................................................... 26 ASTHMA PREVENTERS ....................................................................................................................................... 26ASTHMA QUICK RELIEVERS :....................................................................................................................................... 28 2
  3. 3. Department of Pharmacy Practice and Clinical PharmacyDRUGS FOR GASTROINTESTINAL DISORDERS ...................................................................................................... 29 PEPTIC ULCER DRUGS ........................................................................................................................................ 29 ANTI-PROTOZOA DRUGS .................................................................................................................................... 30 ANTISPASMODICS ............................................................................................................................................. 31 IRRITABLE COLON DRUGS ................................................................................................................................... 32 ANTI-EMETICS.................................................................................................................................................. 32ANTI-VERTIGO DRUGS .............................................................................................................................................. 33 HEPATIC & LIPOTROPIC DRUGS ........................................................................................................................... 34 ANTI-INFECTIVE AGENTS FOR GI DISTURBANCES AND DIARRHEA ................................................................................ 35 LAXATIVES ...................................................................................................................................................... 35 ANTI HEMORRHOIDS ......................................................................................................................................... 36 ANTI-DYSPEPSIA DRUGS: ................................................................................................................................ 37DRUGS FOR BONE DISORDERS ............................................................................................................................ 39 DRUGS AFFECTING BONE METABOLISM ................................................................................................................. 39 ANTI-HYPERURICEMIA DRUGS............................................................................................................................. 40DRUGS FOR ENDOCRINE DISORDERS................................................................................................................... 41 ORAL HYPOGLYCEMIC DRUGS ............................................................................................................................. 41INSULIN SECRETAGOGUE: ........................................................................................................................................... 41NON SULFONYLUREA INSULIN SECRETAGOGUE:.............................................................................................................. 41BIGUANIDE: ............................................................................................................................................................ 42INSULIN SENSITIZERS: ................................................................................................................................................ 42Α GLYCOSIDASE INHIBITORS ........................................................................................................................................ 43NEW HYPOGLYCEMICS .............................................................................................................................................. 43COMBINATIONS: ...................................................................................................................................................... 43 INSULIN .......................................................................................................................................................... 44 THYROID DISORDER DRUGS ................................................................................................................................ 45DRUGS FOR UROLOGIC DISORDER ...................................................................................................................... 46 BENIGN PROSTATE HYPERPLASIA DRUGS ............................................................................................................... 46 ERECTILE DYSFUNCTION DRUGS ........................................................................................................................... 47RENAL AND URINARY ANTISEPTIC ............................................................................................................................... 48ANTIBIOTICS ........................................................................................................................................................ 49 3
  4. 4. Department of Pharmacy Practice and Clinical Pharmacy CELL WALL SYNTHESIS INHIBITORS ....................................................................................................................... 49Β-LACTAMS ............................................................................................................................................................ 49OTHERS ................................................................................................................................................................. 52 PROTEIN SYNTHESIS INHIBITORS .......................................................................................................................... 53TETRACYCLINE GROUP ............................................................................................................................................... 53AMINOGLYCOSIDES................................................................................................................................................... 53MACROLIDES........................................................................................................................................................... 53CHLORAMPHENICOL.................................................................................................................................................. 54 DNA REPLICATION INHIBITOR ....................................................................................................................... 55 ANTI-METABOLITES........................................................................................................................................... 56 ANTI-TUBERCULAR DRUGS.................................................................................................................................. 56MISCELLANEOUS DRUGS ..................................................................................................................................... 57 OPHTHALMIC PREPARATIONS ............................................................................................................................. 57 NASAL PREPARATIONS ...................................................................................................................................... 58 ANTI-ALLERGY ................................................................................................................................................. 59 SMOKING CESSATION: ....................................................................................................................................... 59 CORTICOSTEROIDS ............................................................................................................................................ 60 COMMON COLD AND INFLUENZA......................................................................................................................... 60 ANTI-EDEMA ................................................................................................................................................... 60 VITAMINS ....................................................................................................................................................... 61NEW DRUGS IN EGYPTIAN MARKET 2010 ...................................................................................................... 62TRADE NAMES INDEX....................................................................................................................................... 63 4
  5. 5. Department of Pharmacy Practice and Clinical Pharmacy Drugs for Neurologic Disorders  Pain ManagementAnalgesic, Anti-inflammatory and Anti- pyretic drugs Pharmacology Active Most Frequently Similar Product Names Constituents Dispensed Celecoxib Celebrex® celoxib® NSAID (Selective COX 2 Inhibitor) Meloxicam Mobic® Anticox II® Piroxicam Feldene® Brexin® Lornoxicam Xefo® NSAID (Nonselective Ibuprofen Brufen® Marcofen® COX inhibitor) ® ® ® Ketoprofen Ketofan Profenid Bi-Profenid (150mg) Ibuprofen + Megafen Combination Paracetamol 5
  6. 6. Department of Pharmacy Practice and Clinical Pharmacy Pharmacolo Active Most Frequently Dispensed Similar Product gy Constituents Names Diclofenac Sodium Voltaren® Olfen® Anuva® Diclofenac sodium Dolphin® (suppository) Voltaren® (suppository) Diclofenac Catafast® (sachets) Catafly® Potassium NSAID Diclofenac Cataflam® Oflam®(Nonselective PotassiumCOX inhibitor) Aceclofenac Bristaflam Amoflam ® ® Indomethacin Indocid Indomethacin ® Metamizole = Novalgin Oblong * Dipyrone *Safety concerns (Agranulocytosis) Hints: 6 -profen, -fenac, -oxicam = NSAIDs
  7. 7. Department of Pharmacy Practice and Clinical PharmacyAnalgesic and AntipyreticsPharmacology Active Most Frequently Dispensed Similar Product Names Constituents ® ® ® Panadol Abimol / Cetal Paracetamol Excedrin® Markadel® ASA + Caffeine + Paracetamol Panadol Extra® Abimol Extra®Analgesic andAntipyretic drugs Caffeine + Paracetamol Cevamol® (eff.) Paracetamol + Vit. C Aspirin C® (eff.) Aspro® (eff.) Aspirin + Vitamin COpioid analgesics Pharmacology Active Most Frequently Similar Product Names Constituents Dispensed Tramadol® Trama SR® Tamol® Tramadol HCl Ultradol® μ-opioid Receptor agonist & NE,5-HT- modulator Imigran® Sumagrai®n Sumatriptan succinate 7
  8. 8. Department of Pharmacy Practice and Clinical PharmacyMigraine drugs Pharmacology Active Most Frequently Dispensed Similar Product Constituents Names ® No-Migrain Ergotamine+ Caffeine + paracetamol+ Domperidone combination ® Migranil (Nile Company) prescribed medication only Ergotamine + Caffeine + Memprobamate +analaginSkeletal Muscle Relaxants Pharmacolog Active Most Frequently Dispensed Similar Product Names y Constituents S.M.R® Roysan® 5HT-1 Receptor Tizanidine agonist Myofen® Mark fast® Chlorzoxazone + Ibuprofen Mylogin® Relaxon®, myoflex®Alpha2-Adrenergic agonist Chlorzoxazone + Paracetamol ® Flexofan Chlorzoxazone + Ketoprofen Dantrelax® Dantrolene Skeletal muscle sodium + relaxant Paracetamol 8
  9. 9. Department of Pharmacy Practice and Clinical Pharmacy  Anti-convulsants Pharmacology Active Constituents Most Frequently Similar Product Names Dispensed ® ® Phenytoin Ipantin Phenytoin Phenytoin ® Valeproate sodium Depakine Valproic acid Lamotrigine Lamictal® Lamotrine®Na+ channel blocker Carbamazepine Tegretol® Tegral® Anticonvulsant, Miscellaneous Gabapentin Gaptin® Neurontin® Anticonvulsant, Conventin® Miscellaneous 9
  10. 10. Department of Pharmacy Practice and Clinical Pharmacy  Anti-parkinson’s Drugs Pharmacology Active Most Frequently SimilarProduct Constituents Dispensed Names ® Dopamine Levodopa + Sinemet Precursor Carbidopa Anticholinergic/ Biperiden Aknetoin® Antimuscarinic HCL  Brain Disorders Pharmacology Active Most Frequently Dispensed Similar Product Names ConstituentsPeripheral Vasodilator Vincamine Oxybral® increasing cerebral blood circulation 10
  11. 11. Department of Pharmacy Practice and Clinical Pharmacy Drugs for Psychiatric Disorders  Sedatives & Anxiolytics drugs Pharmacology Active Most Frequently Dispensed Similar Product Constituents Names Xanax® Zolam ® Restolam® Intermediate acting Alprazolam BDZ ® Neuril/ valinil® Valpam Long acting BDZ Diazepam Calmepam® Lexotanil ® Intermediate- Bromazepam short acting BDZ Apetryl®* Amotril® Long Clonazepam acting BDZ Dormicum® Short acting midazolam BDZ Kava® Non Kava kava benzodiazepines extract*Table2 Hints: -bital= barbiturate 11 -zepam, -zolam = BDZ
  12. 12. Department of Pharmacy Practice and Clinical Pharmacy  Alzheimer’s disease Drugs Pharmacology Active Most Frequently Similar Product Constituents Dispensed Names ® ® Acetylcholine Donepezil Aricept Donhimer esterase Inhibitor(AChEI)  Anti-depressants Pharmacology Active Most Frequently Dispensed Similar Product Constituents Names Clomipramine Anafronil® HCl TCA Nortriptyline Motival® 10.0 mg + Fluphenazine Escitalopram Cipra pro® cipralex® Sertraline HCl Lustral®Selective serotoninreuptake inhibitors (SSRI) Fluoxetine Prozac® Durazac® (once Philozac® weekly) ®5-HT & NE reuptake Venlafaxine HCl Efexor inhibitor (SNRI) Hints: 12 -tyline, -pramine = TCA
  13. 13. Department of Pharmacy Practice and Clinical Pharmacy  Anti-psychoticsPharmacology Active Most Frequently Dispensed Similar Product Names Constituents ® Sulpiride Dogmatil Typical (selective postsynaptic D2-receptors antagonist) ® Clozapine Leponex® Clozapex * Atypical (DA&5-HT receptor agonist) olanzapine Zyprexa® Olapex®, olazine® * Clozapex: black Box warning for Agranulocytosis and seizures. 13
  14. 14. Drugs for Cardiovascular Disorders  Anticoagulants Pharmacology Active Constituents Most Frequently Similar Product Names Dispensed heparin Calcium Calheparine® Heparins Enoxaparin calcium Clexane® ®Low Molecular Weight Tinzaparin Innohep ® Heparin Nadroparin Fraxiparine Strepokinase Angikinase® Sedonase®Fibrinolytic Enzymes Warfarin Sodium Marevan® Inhibits Vit K- dependent clotting factors Hints: -parin = (example: Heparin) Anticoagulants
  15. 15. Department of Pharmacy Practice and Clinical Pharmacy AntiplateletsPharmacology Active Most Frequently Dispensed Similar Product Names Constituents ® ® NSAID(COX Acetyl Aspocid Infant Aspirin inhibitor) Salicylate ® ®, ® ADP receptor Clopidogrel Plavix Stroka Mtogrel blocker Capillary stabilizing drugs Pharmacology Active Most Frequently Dispensed Similar Product Names Constituents Vasoconstrictor Diosmin Dioven® (NE )Oral phlebotropic Diosmin + Daflon® Dafrex® drug HesperidinPeripheral venous Amorphous Reparil® and capillary Aescin + diethy stabilizer amine salicylate Venous and Almitrine Duxil®capillary disorder bismesylate + Stabilizer Raubasine 15
  16. 16. Department of Pharmacy Practice and Clinical Pharmacy  Anti-arrhythmic drugs Pharmacology Active Most Frequently Dispensed Similar Product Names Constituents Positive inotropic Digoxin Lanoxin® effect + + ( Na /K ATPase pump inhibitor)Na+ channel blocker Propafenone Rytmonorm® (Class1C) HCl ®K+ channel blocker Amiodarone Cordarone (ClassIII)  Anti-angina drugs Pharmacology Most Frequently Dispensed Similar Product Names Active Constituents Nitromack® Nitroderm® (patchs) Nitroglycerin Dinitra® Cardiket® Isosorbide Vasodilator dinitrate(Organic nitrates) ® ® Effox Monomack Isosorbide mononitrate ® ® 3-KAT inhibitor* Vastarel Metacardia Trimetazidine (Ketoacyl CoA di-HCl thiolase) 16
  17. 17. Department of Pharmacy Practice and Clinical Pharmacy  Anti-Hypotensives Active Most Frequently Dispensed Similar Product Names Pharmacology Constituents Etilefrine Effortil® Vascon® Vasoconstrictor Alpha/Beta AgonistThe mechanism ofheptaminols therapeutic Heptaminol Corasore®actions is not well understoodalthough it has been suggestedto affect catecholamine releaseor calcium metabolism.Read more athttp://www.wrongdiagnosis.com/medical/heptaminol.htm?ktrack=kcplink 17
  18. 18. Department of Pharmacy Practice and Clinical Pharmacy  Anti-Hypertensives Active Most Frequently Dispensed Similar Product Names Pharmacology Constituents ® ® Atenolol Tenormin Blokium Selective β1-Blocker ® ® ® Bisoprolol Concor , concor Cor Bisocard Metoprolol Betaloc® Propranolol Inderal® Indolol® HCl(Combined α& β Blocker) Non-selective ® ® ® Carvedilol Dilatrol Cardilol , Dilatrend Hints: -olol = β Bloker 18
  19. 19. Department of Pharmacy Practice and Clinical PharmacyPharmacology Active Most Frequently Dispensed Similar Product Names Constituents ® ® Atenolol + Tenoretic Blokium Diu Chlorthalidone Tenedone® Bisoprolol + Concor Plus® Bisocard Plus®, Combination Hydrochlorothiazide  Lodoz® Carvedilol + Co-Dilatrol® hydrochlorothiazide Hints: -olol = β Bloker -thiazide = Thiazide diuretic 19
  20. 20. Department of Pharmacy Practice and Clinical Pharmacy Active Most Frequently Dispensed Similar Product Names Pharmacolgy Constituents ® ® Furosemide Lasix Lafurex Loop diuretics Indapamide Natrilix SR® Diurix® thiazide diuretic Non- Aldactone® Spironolactone® (AldosteronePotassium- antagonist) diuretics sparing Spironolactone Spironolactone + Aldactazide® Hydrochlorothiazide Diuretic Combination Spironolactone + Lasilactone® Furosemide Amiloride + Moduretic® Yostiretic® Hydrochlorothiazide Hints: -semide = Loop diuretic -thiazide= Thiazide diuretic 20
  21. 21. Department of Pharmacy Practice and Clinical PharmacyPharmacology Active Most Frequently Dispensed Similar Product Names Constituents Captopril Capoten® ® Lotensine , hypopress ® Captopril+ Capozide® Hydrochlorothiazide ACE-I Ramipril Tritace® Lisinopril Zestril® Lisopril® Enalapril maleate Ezapril® Enalapril + Ezapril-Co® hydrochlorothiazide Combination HCTZ + Losartan Hyzaar® Modazar® Fortazaar® (double concentration) Hints: 21 -pril = ACEI
  22. 22. Department of Pharmacy Practice and Clinical Pharmacy Active Constituents Most Similar Product Names Pharmacology Frequently Dispensed Losartan Cozaar® Losartan® Potassium ® Candesartan Atacand Cilexetil ARB Valsartan Tareg® Disartan®Angiotensin telmisartan Micardis®II ReceptorBlocker Valsartan + Co-Tareg®/ Co-Diovan® Hydrochlothiazide ARB+ Diuretic Hints: -sartan = ARBs -thiazide = Thiazide diuretic 22
  23. 23. Department of Pharmacy Practice and Clinical Pharmacy Active Most Frequently Dispensed Similar Product Names Pharmacology Constituents ® ® Altiazem Delay-Tiazem Non-DHP* Calcium Channel Diltiazem HCl blocker ® Isoptin Verapamil Norvasc® Alkapress®, Miodura® DHP Calcium Channel blocker Amlodipine besylate Epilat® Adalat® Nifedipine Minipress® blocker Alpa- Prazosin HCl Aldomet® Epidopa® (Epico acting α - company) Centrally agonist Methyl dopa*DHP: Dihydropyridine Hints: -dipine= Ca+ channel blocker -zocin = α Bloker 23
  24. 24. Department of Pharmacy Practice and Clinical Pharmacy  Lipid regulatory agents Pharmacology Active Most Frequently Dispensed Similar Product Constituents Names ® ® Lipanthyl Arteflex Fibrates Fenofibrate ® ® Lipitor Ator Atorvastatin Zocor ® Simvastat® Simvastatin Lescol XL® Statins (HMG CO-Areductase Inhibitor) Fluvastatin Lipostat® Pravastatin Crestor® Rosuvast® Rosuvastatin Hints: -statin= HMG CO-A reductase Inhibitor 24
  25. 25. Department of Pharmacy Practice and Clinical PharmacyPharmacology Active Most Frequently Dispensed Similar Product Names Constituents ® ® Simvastatin + Inegy Lipitrin Ezetimibe Combination Cholestyramin questran(eg) sachets® cholestran 4gm/s® e Bile acidsequestrants 12s(eg) Fish oil + Omega 3 Plus® Superomega, Wheat Germ omega forte oil Other 25
  26. 26. Department of Pharmacy Practice and Clinical Pharmacy Respiratory Disorders  Asthma PreventersPharmacology Active Most Frequently Dispensed Similar Product Constituents Names Fluticasone Flixotide® propionate Inhaled corticosteroids Budesonide Pulmicort® Miflonide ® Formoterol Foradil® Oxis® fumarate Inhaled long-acting beta2 agonist Salmeterol Serevent® xinafoate Steroid inhalers: Hints: Usually brown and orange in color. -onide= Corticosteroids Some examples are Pulmicort and Flixotide. -terol = β-agonist 26
  27. 27. Department of Pharmacy Practice and Clinical PharmacyPharmacology Active Constituents Most Frequently Dispensed Similar Product Names (A) Budesonide + (A) Symbicort® (B) Seretide ® Formoterol New combination preventers (B) Salmeterol + Fluticasone Montelukast sodium Singulair® Kokast® Anti-leukotrienes Kast® Clear Air® Theophylline Quibron SR® Theo SR®Theophylline Theophylline SR® New combination preventers 27 Red& purple inhalers. Examples are Symbicort and Seretide.
  28. 28. Department of Pharmacy Practice and Clinical Pharmacy Asthma Quick relievers : Active Most Frequently Dispensed Similar Product Names Constituents Salbutamol/ Ventolin® AlbuterolInhaled short-acting beta2 agonist Terbutaline Bricanyl® sulphate Iptrotropium Atrovent® Anticholinergic/ anti-muscarinics bromide Tiotropium Spiriva® bromide Prednisone Hostacortin® oral steroids prednisolone Hostacortin H® Hints: Pred- , -pred , -Cort- = Corticosteroids Quick relievers Usually blue inhalers. Examples are Ventolin and Bricanyl. 28
  29. 29. Department of Pharmacy Practice and Clinical Pharmacy Drugs for Gastrointestinal Disorders  Peptic Ulcer drugsPharmaco Active Most Frequently Dispensed Similar Product Names logy Constituents ® ® Ranitidine Zantac Aciloc H2 Receptors blockers ® ® Famotidine Antodine/ Famotak Servipep/ Peptec Omeprazole Omepak® Pepzol®, Risek® Esomeprazole Nexium® Proton-pump inhibitors Lansoprazole Lanzor® Peptazol® ® ® Pantoprazole Controloc Pantoloc Hints: -eprazole, -oprazole= Proton pump Inhibitors 29
  30. 30. Department of Pharmacy Practice and Clinical PharmacyPharmaco Active Most Frequently Dispensed Similar Product Names logy Constituents ® Omeprazole + Trio * Tinidazole + Triple therapy Doxycycline Trio: used in treatment of PUD caused by H.Pylori  Anti-protozoa drugs Pharmacology Active Most Frequently Dispensed Similar Product Constituents Names Imidazole derivatives Metronidazole Flagyl® Amrizole® Hints: -dazole = Imidazole derivatives 30
  31. 31. Department of Pharmacy Practice and Clinical Pharmacy  AntispasmodicsPharmacology Active Most Frequently Dispensed Similar Product Names Constituents ® ® Hyoscine-N- Buscopan Spasmocin ButylbromideAnticholinergic agent, Hyoscine-N- Buscopan Compositum® Spascolon® Scopolamine Butylbromide + Derivatives Dipyrone ®Anticholinergic Dicyclomine Spasmorest agent HCl ® ® tiemonium Visceralgine Viscera methyl sulphateAntimuscarinic agent ® Camylofin + Spasmo Pyralgin M Analgin ® 5-HT3 Trimebutine Gast-Reg Debridat® Receptor maleate antagonist 31
  32. 32. Department of Pharmacy Practice and Clinical Pharmacy  Irritable colon drugs Pharmacology Active Constituents Most Frequently Dispensed Similar Product Names Mebeverine HCl + Colona® Sulpiride Antispasmodic agent ® Mosapride Fluxopride Prokinitic Clidinium bromide + Librax® Chlordiazepoxide Anticholinergic+ Benzodiazepine  Anti-emetics Pharmacology Active Most Frequently Dispensed Similar Product Names Constituents ® Metoclopramide HCl Primperan Dopamine antagonist Domperidone Motilium® Motinorm® ® Selective 5-HT3 Ondansetron HCl Zofran® EmerestReceptor antagonist Adrenocortical Cortigen b6® (amp) Cortiplex® (amp) Hormone + vit b6 – (pyridoxine) Hints: -serton = Selective 5-HT3 Receptor 32 antagonist [antiemetic]
  33. 33. Department of Pharmacy Practice and Clinical PharmacyAnti-vertigo DrugsPharmacology Active Most Frequently Similar Product Names Constituents Dispensed ® ® Betahistine Betaserc Verserc Histamine H3 agonist Cinnarizine Stugeron®Anti- Histamine 33
  34. 34. Department of Pharmacy Practice and Clinical Pharmacy  Hepatic & Lipotropic drugsPharmacology Active Most Frequently Dispensed Similar Product Constituents Names Silymarin Legalon® Hepaticum® Flavonoids(hepatoprotective) Ursodeoxycholic Ursogall® Ursofalk® acid Gallstone Dissolution Agent D.D.B D.D.B®* Hepacare®Hepatoprotecti ve Menthol + Rowachol® Bilichol®Hepato- & reno- Menthone + biliary Alphapinene Disorders Betapinene + therapy Borneol + Camphene + Cineal + Olive oil Liver albumen® Levanox® Combination *D.D.B: Referred to as the Yellow pill in the Egyptian market 34
  35. 35. Department of Pharmacy Practice and Clinical Pharmacy  Anti-infective agents for GI disturbances and Diarrhea Pharmacology Active Constituents Most Frequently Similar Product Names Dispensed ® ® Nifuroxazide Antinal Diax Oral nitrofuran Antibiotic Tiliquinol + Intetrix® Tilbroquinol Anti-infective  LaxativesPharmacology Active Most Frequently Dispensed Similar Product Names Constituents (A) Bisacodyl (A) Abilaxine® (B) MinaLax® (B) Bisacodyl + Dioctyl Sodium Sulphosucci-nate Stimulant Sodium Picolax® Laxeol-PI® Laxative Picosulphate ® ® Plantago Biolax PlantagoBulk- forming Laxative Ca Polycarbophil Evaculax® 35
  36. 36. Department of Pharmacy Practice and Clinical Pharmacy  Anti hemorrhoidsPharmacology Active Most Frequently Similar Product Names Constituents Dispensed ® ®Local anesthetic, Cinchocaine + Proctosedyl Sediproct hydrocortisone + Anti- Framycetine + inflammatory, Aesculoside Anti-puritic & Anti-spasmodic Hydrocortisone Procto-4® Framycetin Esculin Bismuth subgallate Tribenoside + Proctoglyvenol® lidocainevasoprotective +Local Anesthetic; Hints: -caine = lidocaine 36
  37. 37. Department of Pharmacy Practice and Clinical Pharmacy  Anti-dyspepsia drugs: Pharmacology Active Constituents Most Frequently Similar Product Names Dispensed ® Papain + Sanzyme Digestin Digestive enzymes Neo-Digestin® Papain + Sanzyme + Pepsin cellulose +methixene HCl + Spasmo canulase ® Pancreatin + pepsin + Simethicone+ Na Parasympatholytic dehydrocholate. Nutrizym® Pancreatin + Ox-bile + Proteolytic enzyme Bromelin Papain +Na dehydrocholate + Dicyclomine + Spasmodigestin® Simethicone+SanzymeDigestive, Spasmolytic and Anti-flatulent 37
  38. 38. Department of Pharmacy Practice and Clinical Pharmacy Pharmacology Active Constituents Most Frequently Similar Product Dispensed Names Anti-flatulent Disflatyl® Dimethicone + Silicon dioxide Antacid Rennie® Magnesium carbonate + Ca+ Carbonate. ® Maalox Plus Antacid/ Anti- Aluminium hydroxide + flatulant MgOH + Simethicone Epicogel® Aluminium hydroxide gel + Magnesium hydroxide + Dimethicone Oral antifoaming Luftal® Simethicon® agent Simethicone (polydimethylsiloxane and silica gel.) ®Activated Charcoal Eucarbon Activated Charcoal + Senna + Carbon + Rhubarb + peppermint oil + sulpher+ fennel oil 38
  39. 39. Department of Pharmacy Practice and Clinical Pharmacy Drugs for Bone Disorders Drugs affecting bone metabolismPharmacology Active Constituents Most Frequently Dispensed Similar Product Names ® Salmon calcitonin Miacalcic calcitonin® Calcitonin (A) Alendronate + (A)Fosavance® (B)Fosamax® Colicalciferol (B) AlendronateBisphosphonate Derivative Risedronate Sodium Actonel® Hints: -dronate = Bisphosphonate 39
  40. 40. Department of Pharmacy Practice and Clinical Pharmacy Anti-Hyperuricemia drugsPharmacology Active Most Frequently Dispensed Similar Constituents Product Names Allopurinol Zyloric® No Uric® Xanthine Oxidase Inhibitor ® ® piperazine + Urosolvine Urivin colchicine+atropine+ sodium citrate Uricosuric 40
  41. 41. Department of Pharmacy Practice and Clinical Pharmacy Drugs for Endocrine Disorders  Oral Hypoglycemic drugs Insulin Secretagogue:Pharmacology Active Most Frequently Dispensed Similar Product Names Constituents Gliclazide Diamicron® Sulfonylurea (1st Generation) Glibenclamide Daonil® Diaben® Sulfonylurea (2nd Generation) Glimepiride Amaryl® Dolcyl® Sulfonylurea (2nd Generation) Non Sulfonylurea Insulin Secretagogue: Pharmacology Active Most Frequently Dispensed Similar Product Names Constituents Repaglinide NovoNorm® Repaglide® Meglitinides 41
  42. 42. Department of Pharmacy Practice and Clinical Pharmacy Biguanide:Pharmacology Active Most Frequently Dispensed Similar Product Names Constituents Metformin Glucophage® Cidophage® Hydrochloride Biguanide Insulin sensitizers: Pharmacology Active Most Frequently Similar Product Names Constituents Dispensed Pioglitazone Glustin® Hi glitazone®Thiazolidinedione(Insulin sensitizer) Hints: -glitazone = Thiazolidinedione 42
  43. 43. Department of Pharmacy Practice and Clinical Pharmacy α Glycosidase Inhibitors Pharmacology Active Most Frequently Dispensed Similar Constituents Product Names α Glycosidase Acarbose Glucobay® Inhibitors New Hypoglycemics Pharmacology Active Most Frequently Dispensed Similar Product Constituent Names s Dipeptidyl sitagliptin Januvia® Peptidase IV (DPP-IV) Inhibitor Hints: -gliptin = DPP-4 enzyme inhibitorCombinations: Pharmacology Active Most Frequently Dispensed Similar Product Constituents Names Glucovance® Glimet® Glibenclamide + Metformin Sulfonylurea (2nd)+ biguanide ® Diavance Glypuride + Metformin 43
  44. 44. Department of Pharmacy Practice and Clinical Pharmacy  InsulinPharmacology Active Most Frequently Similar Product Names Constituents DispensedRapid Acting Insulin Rapid Lispro® Aspart® Insulin acting Crystalline Humulin-R® Actrapid® (Regular Insulin)Short Acting Insulin ® ® insulin isophan Insulatard Humulin N (NPH insulin)Intermediate-Acting Insulin Insulin glargine Lantus® Long acting (Glargine) insulin Insulin humulin70/30® isophan70%+re Mixtard® gular 30%Combination 44
  45. 45. Department of Pharmacy Practice and Clinical Pharmacy  Thyroid Disorder drugsPharmacology Active Most Frequently Similar Product Constituents Dispensed Names ® ® thyroxin Sodium Eltroxin Euthyrox (L-thyroxine) Anti-hypothyroidism Carbimazole Carbimazole® Neomercazol® Anti- ®hyperthyroidism Propylthiouracil Thyrocil 45
  46. 46. Department of Pharmacy Practice and Clinical Pharmacy Drugs for Urologic Disorder  Benign Prostate Hyperplasia drugs Pharmacology Active Most Frequently Similar Product Names Constituents Dispensed Doxazosin Cardura® Dosin® Terazosin Itrin® α- blocker Tamsulosin Tamsulin® Tamic®5 α- reductase Finasteride Proscar® Prostat® Inhibitors Pumpkin Pepon® Procure® seed oil others Hints: -afil = α-blocker 46
  47. 47. Department of Pharmacy Practice and Clinical Pharmacy Erectile dysfunction drugs Pharmacology Active Most Frequently Similar Product Constituents Dispensed Names Sildenafil Citrate Viagra® Virecta®Phosphodiesterase- 5-Inhibitor Tadalafil Cialis® Snafi® Hints: -afil = Phosphodiesterase-5-Inhibitor 47
  48. 48. Department of Pharmacy Practice and Clinical Pharmacy Renal and Urinary AntisepticPharmacology Active Most Frequently Dispensed Similar Product Constituents Names Proximol® ??? Halphabarol Urosolvine® UR-AID® Atropine Sulphate + Colchicine +Combination Piperazine Rowatinex® Urinex® Betacamphene+fe nchone+pinene, anethol, borneol, camphene, cineol, olive oil Anti- Spasmo rowatinex®Spasmodic oils (Supp.) Fenchone, anethol, Betacamphene, cineole 48
  49. 49. Department of Pharmacy Practice and Clinical Pharmacy Antibiotics  Cell wall Synthesis Inhibitors β-LactamsPharmacology Active Most Frequently Dispensed Similar Product Constituents Names Retarpen® Penicillin G Sodium® Benzyl penicillin Phenoxymethyl Ospen® penicillin ® Ampiclox Ampicillin + Penicillins Cloxacillin Unasyn® Unictam® Sulbactam + Ampicillin Amoxil® Hiconcil® Amoxicillin Hints: -cillin= β-lactam 49
  50. 50. Department of Pharmacy Practice and Clinical PharmacyPharmacolog Most Frequently Similar Product Active Constituents y Dispensed Names ® ® Augmentin Hibiotic Amoxicillin + Clavulanic acid combination Penicillins ® Flumox® Flucamox Amoxicillin + flucloxacillin Ceporex® Keflex® CephalexinCephalosporins 1 Generation Duricef ® Curisafe® Cefadroxil st Velosef ® Fortecef ® Cephradine Hints: Ceph- = first generation Cephalosporins except Cefazolin 50
  51. 51. Department of Pharmacy Practice and Clinical PharmacyPharmacology Active constituents Most Frequently Dispensed Similar Product Names ® Ceclor Bacticlor 2nd GenerationCephalosporins Cefaclor ® Zinnat Cefuroxime Cefobid® (b.i.d twice daily) Cefrone ® Cefoperazone Claforan® Cefotax®Cephalosporins 3rd Generation Cefotaxime Oframox® Rocephen® (Roche Company) Ceftriaxone Hints: Cef- = Cephalosporin -fa-, -fam-, -fox-, -tea-, -fur- = 2nd Generation Cephalosporins Exceptions : cefmetazole , cefonicid , cefprozil , loracarbef Tri or t = 3rd Generation cephalosporins (parental preparations) 51
  52. 52. Department of Pharmacy Practice and Clinical PharmacyPharmacology Most Frequently Dispensed Similar Product Names ® Cefprozil Cefzil Ceftazidime Fortum ® Cefzim® rd 3 Generatio n Cefpodoxi Orelox®Cephalosporins m Cefdinir Omnicef ® Cefepime Maxipime® Wincef® 4th generati on OthersPharmacology Active Constituents Most Frequently Similar Product Names Dispensed Others Vancomycin Vancomycin® Vancocin® linezolid Averozolid 600® 52
  53. 53. Department of Pharmacy Practice and Clinical Pharmacy  Protein Synthesis InhibitorsPharmacology Active Most Frequently Similar Product Names constituent Dispensed ® ® Tetracycline Hostacycline Tetracid (Cid Company) Tetracycline group ® ® Doxycycline Doxymycin Farcodoxin (Pharco company) Gentamicin Garamycin® Gentamicin®Aminoglycos ides Tobramycin Tobracin® Tobcin® Erythromycin Erythromycin® Erythrocin® Azithromycin Zithromax® Azolide® Zithrocan® Macrolides Clarithromycin Klacid® Spiramycin Rovac® Rovamycin® 53
  54. 54. Department of Pharmacy Practice and Clinical PharmacyPharmacology Active constituent Most Frequently Similar Product Dispensed Names Lincosamides Clindamycin Clindam® Dalacin-C® group Miphenicol® (Misr Chloramphenico Company) l Chloramphenicol Cidocetine Hints: -cycline : tetracycline -mycin: aminoglycoides, Macrolide, lincosamides 54
  55. 55. Department of Pharmacy Practice and Clinical Pharmacy  DNA Replication Inhibitor Pharmacolo Active Most Frequently Dispensed Similar Product Names gy constituent ® ® ciprofloxacin Ciprofar Ciprobay Gatifloxacin Gasticin, gatilox Tequin Levofloxacin Tavanic® Tavacin®Quinolones * ® ® ® Noracin Kiroll Tarivid ofloxacin *Should not be used with patients under 18 years old Hints: -floxacin : Quinolones 55
  56. 56. Department of Pharmacy Practice and Clinical Pharmacy  Anti-metabolitesPharmacology Active constituents Most Frequently Dispensed Similar Product Names ®Folic acid Sulphamethoxazole Septrin- D.S. Sutrim forte®synthesis + trimethopriminhibitors (TMP + SMZ)  Anti-tubercular drugs Pharmacol Active Most Frequently Dispensed Similar Product Names ogy constituents Rifampicin Rimactane® (Rifampin) ® Rifampicin Rimactazid Rifam plus® +Isoniazid Streptomycin Streptomycin 56
  57. 57. Department of Pharmacy Practice and Clinical Pharmacy Miscellaneous Drugs  Ophthalmic PreparationsTherapeutic Pharmacology Active Most Frequently Dispensed Similar Product Class Constituents Names Adrenergic Tetrahydrozoline Visine® Occuzoline® Agonist AgentDecongestant andAntihistaminic Eye Drops ® ® Aminoglycosides Tobramycin Tobrex TobralexAntibacterial Eye Drops Aminoglycoside/ Tobramycin and Tobradex® Optidex-T® Corticosteroid DexamethasoneAntibacterial &Corticosteroid Eye Drops Methylhydroxyprop Tears Natural® Tears Guard® ylcellulose (Hydroxy propyl methylcellulose)Preparationsfor Dryness of the Eye Carboxymethylcellulose Refresh plus®* Refresh tears® ® ® Corticosteroid Prednisolone Pred forte Echonopred Plus , ® Acetate solupredDrops for Eye Allergy andInflammation 57
  58. 58. Department of Pharmacy Practice and Clinical Pharmacy Therapeutic Pharmacology Active Constituents Most Frequently Similar Product Class Dispensed Names Histamine H1 Chlorpheniramine Prisoline® Optozoline® Antagonist + Maleate + Decongestant and Anti- Alpha 1 Agonist Naphazoline histaminic and HydrochlorideAnti-allergic Eyeand Nasal Drops *Refresh plus: each dose in separate pack.  Nasal Preparations Therapeutic Pharmacology Active Most Similar Product Class Constituents Frequently Names Dispensed Fluticasone Flixonase® Ticanase® Propionate Nasal Anti-Allergic Corticosteroid Oxymetazoline Afrin® Oxymet® HCl Decongestant Xylometazoline Otrivin® Balkis®, HCl Nasostop® Vasoconstrictor (α- receptor Nasal Decongestant stimulant) ® ® Sod. Nasotal Nazocrom Cromoglycate Mast cell stabilizerchimpchimp Hints: -olone = Corticosteroids 58

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