Types of parentrals mahesh

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Classification Of Parenterals,
Small Volume Parenterals: Defn & Components,
Large Volume Parenterals: Defn & Introduction,
Types of LVP,
Examples Of IV fluids,
Difference Between SVP & LVP,

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Types of parentrals mahesh

  1. 1. Types of Parentrals<br />By :<br />Mr. Mahesh Wamanrao Thube,<br />Govt. College Of Pharmacy, A’Bad.<br />
  2. 2. Content: At A Glance<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />2<br />Classification Of Parenterals,<br />Small Volume Parenterals: Defn & Components,<br />Large Volume Parenterals: Defn & Introduction,<br />Types of LVP,<br />Examples Of IV fluids,<br />Difference Between SVP & LVP,<br />References<br />
  3. 3. Classification Of Parenterals<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />3<br />
  4. 4. Small Volume Parenterals<br />USP Defn: An Injection that is packed in containers labeled as containing 100 mL or less<br /><ul><li>Components of SVP</li></ul>Vehicle:<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />4<br />
  5. 5. 7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />5<br />
  6. 6. Large Volume Parenterals<br />Defn: LVP are Parenterals designed to provide -Fluid(water), -Calories(Dextrose soln), -Electrolytes(Saline soln), or -Combination of these.<br />Volume 101-1000mL<br />IV infusion technique is “Venoclysis”.<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />6<br />
  7. 7. Requirements for LVP<br />Sterile, Non Pyrogenic, Free from Particulate matter<br />Volume 101-1000mL,<br />Single dose unit,<br />No Preservative,<br />Clear solution except Fat Emulsion,<br />Isotonic, but Hypertonic also administered in TPN.<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />7<br />
  8. 8. 7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />8<br />Types of Large Volume Parenterals<br />
  9. 9. 1.Hyperalimentation Solution<br />Adm. Of large amt. of nutrients to patients who unable to take food orally, at caloric intake of 4000 kCal/day.<br />Subclavian vein cannulation : Infusion of Hypertonic soln.<br />Formulation : mix. Of Dextrose, Amino acids, Lipids, Electrolytes, & Vitamins.<br />Use: 1.Adm. of Life saving/sustaining drug to Comatose patient.<br /> 2.Patient undergoing t/t of GI disease<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />9<br />
  10. 10. Total Parenterals Nutrition<br />Modified term for Hyperalimentation<br />Defn: IV adm. Of Caloric, Nitrogen, & other nutrients in sufficient qt. to achieve tissue synthesis & anabolism <br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />10<br />
  11. 11. Indication For Use of TPN<br />GI disease,<br />Major trauma, Septicemia,<br />Major Abdominal Surgery,<br />Malignancy of Small Bowel,<br />Radiation Enteritis,<br />Chemotherapy & Radiotherapy,<br />Bone Marrow Transplantation,<br />Prolonged Coma.<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />11<br />
  12. 12. 2. Cardioplegic Solutions<br />Are LVP used in Heart surgery to prevent injury to myocardium during reperfusion, as well as to maintain bloodless operating field.<br />Maintains the Diastolic arrest.<br />Adm. In cold form.<br />Slightly alkaline to compensate Metabolic acidosis,<br />Hypertonic<br />Use: To minimize reperfusion injury resulting from tissue edema<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />12<br />
  13. 13. 3. Peritoneal Dialysis Solution<br />Infused continuously into abdominal cavity, bathing peritoneum & are then continuously withdrawn.<br />Formulation:- Glucose ,<br /> - Antibiotics as Prophylactic<br />Use:<br />Removal of toxic substances from body.<br />To aid & accelerate excretion normal.<br />To treat acute renal insufficiency <br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />13<br />
  14. 14. 4.Irrigating solutions<br />To irrigate, flush & aid in cleansing body cavities & wounds.<br />Certain IV soln(Normal Saline) may be used as irrigating soln, but soln designed as Irrigating soln should not be used Paretentrally.<br />Use: treatment of serious wounds infused into blood stream.<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />14<br />
  15. 15. Examples Of LVP fluids<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />15<br />
  16. 16. Difference Between SVP & LVP<br />7 October 2009<br />16<br />
  17. 17. Continued..<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />17<br />
  18. 18. References<br />Modern Pharmaceutics Fourth Edition, Revised and Expanded, Edited By G.S.Banker & C.T.Rhodes, Marcel Dekker pg387-389.<br />The Science & practice of Pharmacy, By Remington, Vol-01, Edi.21st, Lippincott Publication, pg-838-840.<br />Pharmaceutical Dosage Forms. Vol. 3 : Parenteral Medications, Pub Informa Healthcare, Edi. Avis, Kenneth E, Vol I, pg173-180<br />http://melindo.co.id/images/respiratory.jpg<br />www.weiler-bfs.com<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />18<br />
  19. 19. Thank You………..<br />7 October 2009<br />Govt. College Of Pharmacy, Aurangabad<br />19<br />

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