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COGS 107B - Winter 2010 - Lecture 2 - proprioception and the vestibular system
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COGS 107B - Winter 2010 - Lecture 2 - proprioception and the vestibular system


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COGS 107B - Winter 2010 - Lecture 2 - proprioception and the vestibular system

COGS 107B - Winter 2010 - Lecture 2 - proprioception and the vestibular system

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  • Spinal nerve containing afferent DRG, ventral root, dorsal root, dorsal horn, ventral horn, grey matter, white matter, intermediate zone
  • Transcript

    • 1. Cogs 107b – Systems Neuroscience lec01072010 – proprioception and the vestibular system the weekly principle(s): ‘the neuron doctrine’ and ‘law of dynamic polarization’ 1
    • 2. sensory organ receptors: across different sensory modalities, anatomical features of sensory organ receptors determine the dynamics of their electrical activity and, within a modality, the type of sensory information they convey
    • 3. proprioception and touch sense: the ‘all-axon’ ganglion cell
    • 4. a simple proprioceptive circuit / system – the knee-jerk reflex
    • 5. the muscle spindle: activation by muscle elongation / stretch is modulated by contraction state of the muscle
    • 6. the Golgi tendon organ: registering tendon stretch (= muscle contraction)
    • 7. functions of proprioception: - joint-protecting reflexes (e.g., knee-jerk) - adjustment of muscle contraction / recruitment - kinesthesia: detection of body position and movement - coordination of motor commands - sense of self?
    • 8. dorsal root ganglion pathways to the brain
    • 9. somatosensory cortex: integration of proprioceptive and tactile information
    • 10. the Pinnochio effect the Pinocchio effect
    • 11. functions of the vestibular system: - postural reflexes - gaze adjustment - assessment of self motion - a reason not to drink too heavily?
    • 12. the ‘hair cell’ receptor – transduction of both head motion (vestibular system) and sound waves (auditory system) into neural signals
    • 13. the ‘hair cell’ receptor – transduction of both head motion and sound
    • 14. the inner ear
    • 15. orthogonal orientation of the semicircular canals and otolith organs
    • 16. semicircular canals: hair cell registration of rotational velocity, orthogonality, and the L/R push-pull system
    • 17. registration of linear translation and static head position via the otolith organs, the utricle and saccule registration of rotational velocity of the head (about the trunk) via the semicircular canals
    • 18. utricle and saccule: registration of static head position (relative to ground / gravity), orthogonality, and the hair cell population code
    • 19.  
    • 20. vestibular afferents: pathway to the brain and spinal cord
    • 21. integrating vestibular signals I – the vestibulo-ocular reflex – adjusting and maintaining gaze during head movements
    • 22. integrating vestibular signals II – the ubiquitous ‘head-direction’ neuron
    • 23.