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Metabolisme protein dan asam amino
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Metabolisme protein dan asam amino

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  • 1. Metabolisme Protein dan Asam Amino Annisa N.A Dwinda Listya Lulut Handoyo Ni Komang Ayu Febi W. Yohana S.M
  • 2. Protein Penggolongan :1. Protein Fibrous (Serat) Protein yang tidak larut dalam air. Misal : keratin, kolagen, sutra2. Proterin Globular Protein yang larut dalam air. Misal : enzim, hormon, hemoglobin, mioglobin, ovalbumin (pada putih telur)
  • 3. Struktur Protein Struktur primer protein • Rantai peptida yang dihubungkan oleh ikatan peptida H R O H R O H R O H R ON C C N C C N C C N C C H H H H
  • 4. Struktur Protein Sekunder
  • 5. Degradasi Asam Amino Degradasi as amino pd mamalia berlangsung di liver Degradasi gugus α-amino Degradasi rantai karbon
  • 6. Degradasi Gugus Asam Amino Gugus α-amino dari asam amino ditransfer menjadi α- ketoglutarat membentuk glutamat oleh enzim aminotransferase Glutamat mengalami deaminasi oksidatif menghasikan ion NH4+ dikatalis oleh enzim glutamat dehidrogenase menggunakan NAD + atau NADP+
  • 7. Reaksi Degradasi Gugus Asam Amino
  • 8. Hasil Reaksi Katalis a-amino Reaksi yang dikatalis oleh aminotransferase & glutamat dihidrogenase : Asam α-amino + NAD+ (atau NADP+)+ H2O ® asam α-keto +NH4+ + NADH (atau NADPH)+ H+