HSC 340  9-2-10 <ul><li>What is cancer? </li></ul><ul><li>Tumor Classification </li></ul><ul><li>Detection </li></ul><ul><...
What is cancer?  <ul><li>Cancer Initiation: </li></ul><ul><ul><li>Abnormal cellular proliferation/Mutations </li></ul></ul...
 
Tumor Growth <ul><li>Cell Cycle </li></ul><ul><ul><li>G0, G1, S, G2, M </li></ul></ul><ul><ul><li>YouTube - Cell Cycle </l...
Classification (Ch. 1 Pg 5) <ul><li>Benign </li></ul><ul><ul><li>Well differentiated </li></ul></ul><ul><ul><li>Do not met...
Types of cancers <ul><li>Carcinomas </li></ul><ul><li>Sarcomas </li></ul><ul><li>Leukemia </li></ul><ul><li>Lymphoma and m...
Detection <ul><li>Screening Examinations </li></ul><ul><ul><li>Physical exams </li></ul></ul><ul><ul><ul><li>DRE </li></ul...
 
Staging <ul><li>TNM </li></ul><ul><ul><li>T size or extent of tumor </li></ul></ul><ul><ul><li>N lymph node status </li></...
Treatment <ul><li>Surgery </li></ul><ul><li>Chemotherapy (table 1-5) </li></ul><ul><li>Radiation Therapy </li></ul><ul><ul...
Patterns of Spread (Ch. 1 pg.18) <ul><li>Blood, Lymphatic, Seeding </li></ul><ul><li>Depends on site of primary </li></ul>...
Prognosis <ul><li>Estimation of life expectancy  </li></ul><ul><li>Based upon: </li></ul><ul><ul><li>Natural History </li>...
Radiation Oncology Team <ul><li>Radiation Oncologist </li></ul><ul><li>Radiation Physicist </li></ul><ul><li>Dosimetrist <...
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Hsc 340

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Hsc 340

  1. 1. HSC 340 9-2-10 <ul><li>What is cancer? </li></ul><ul><li>Tumor Classification </li></ul><ul><li>Detection </li></ul><ul><li>Staging </li></ul><ul><li>Treatment </li></ul><ul><li>Patterns of spread </li></ul><ul><li>Prognosis </li></ul><ul><li>Radiation Oncology Team </li></ul>
  2. 2. What is cancer? <ul><li>Cancer Initiation: </li></ul><ul><ul><li>Abnormal cellular proliferation/Mutations </li></ul></ul><ul><ul><ul><li>Caused by: </li></ul></ul></ul><ul><ul><ul><li>Environment </li></ul></ul></ul><ul><ul><ul><li>Radiation </li></ul></ul></ul><ul><ul><ul><li>Tobacco </li></ul></ul></ul><ul><ul><ul><li>Genetics </li></ul></ul></ul><ul><ul><ul><li>Chemicals </li></ul></ul></ul><ul><ul><ul><li>Infectious Agents </li></ul></ul></ul>
  3. 4. Tumor Growth <ul><li>Cell Cycle </li></ul><ul><ul><li>G0, G1, S, G2, M </li></ul></ul><ul><ul><li>YouTube - Cell Cycle </li></ul></ul><ul><li>Normal </li></ul><ul><ul><li>Balance between replication and dying of cells </li></ul></ul><ul><li>Tumor growth </li></ul><ul><ul><li>Imbalance between replication and dying of cells </li></ul></ul>
  4. 5. Classification (Ch. 1 Pg 5) <ul><li>Benign </li></ul><ul><ul><li>Well differentiated </li></ul></ul><ul><ul><li>Do not metastasize </li></ul></ul><ul><ul><li>Do not invade </li></ul></ul><ul><li>Malignant </li></ul><ul><ul><li>Well differentiated to undifferentiated </li></ul></ul><ul><ul><li>Can metastasize </li></ul></ul><ul><ul><li>Can invade </li></ul></ul>
  5. 6. Types of cancers <ul><li>Carcinomas </li></ul><ul><li>Sarcomas </li></ul><ul><li>Leukemia </li></ul><ul><li>Lymphoma and myeloma </li></ul><ul><li>CNS cancers </li></ul>
  6. 7. Detection <ul><li>Screening Examinations </li></ul><ul><ul><li>Physical exams </li></ul></ul><ul><ul><ul><li>DRE </li></ul></ul></ul><ul><ul><li>Laboratory tests </li></ul></ul><ul><ul><ul><li>Pap smear, fecal occult blood tests, PSA </li></ul></ul></ul><ul><ul><li>Imaging procedures </li></ul></ul><ul><ul><ul><li>Mammograms, colonoscopies </li></ul></ul></ul><ul><ul><li>Genetic tests </li></ul></ul><ul><li>Awareness </li></ul>
  7. 9. Staging <ul><li>TNM </li></ul><ul><ul><li>T size or extent of tumor </li></ul></ul><ul><ul><li>N lymph node status </li></ul></ul><ul><ul><li>M presence or extent of metastasis </li></ul></ul><ul><li>Surgical staging </li></ul><ul><li>Grade of tumor </li></ul>
  8. 10. Treatment <ul><li>Surgery </li></ul><ul><li>Chemotherapy (table 1-5) </li></ul><ul><li>Radiation Therapy </li></ul><ul><ul><li>External Beam </li></ul></ul><ul><ul><li>Brachytherapy </li></ul></ul><ul><li>Immunotherapy </li></ul>
  9. 11. Patterns of Spread (Ch. 1 pg.18) <ul><li>Blood, Lymphatic, Seeding </li></ul><ul><li>Depends on site of primary </li></ul><ul><ul><li>Prostate (Bone, Liver, Lungs) </li></ul></ul><ul><ul><li>Breast (Lungs, Bone, Brain) </li></ul></ul><ul><ul><li>Lung (Liver, adrenal glands, bone, brain </li></ul></ul><ul><li>Video: How cancer spreads - MayoClinic .com </li></ul>
  10. 12. Prognosis <ul><li>Estimation of life expectancy </li></ul><ul><li>Based upon: </li></ul><ul><ul><li>Natural History </li></ul></ul><ul><ul><li>Grade, Stage, and Tumor Size </li></ul></ul>
  11. 13. Radiation Oncology Team <ul><li>Radiation Oncologist </li></ul><ul><li>Radiation Physicist </li></ul><ul><li>Dosimetrist </li></ul><ul><li>Radiation Therapist </li></ul><ul><li>Nurses </li></ul><ul><li>Clerical Staff </li></ul>

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