DEFINITION Thalassemia is a group of inherited/ hereditary disorders characterized by reduced or absent amounts of hemoglobin or synthesis of hemoglobin.
TWO BASIC GROUPS OF THALASSEMIADISORDER Alpha Thalassemia Beta Thalassemia: A person with this disorder has two mutated genes
TYPES OF BETA THALASSEMIA Beta thalassemia minor– the mildest form of beta thalassemia. Thalassemia trait - heterozygous disorder resulting in mild hypochromic, microcytic hemolytic anemia. Beta thalassemia intermedia - Severity lies between the minor and major. Beta thalassemia major - homozygous disorder resulting in severe transfusion-dependent hemolytic anemia. 6