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1.0 jean-françois delfraissy intro 1.0 jean-françois delfraissy intro Presentation Transcript

  •   3rd International Research Meeting June 10th, 2011, Hôtel Marigny Introduction Pr Jean-François Delfraissy Institut de Microbiologie et Maladies Infectieuses (IMMI) Agence Nationale de Recherche sur le Sida et les Hépatites Virales (ANRS) CHU Bicetre – Paris XI CEA CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRD
  • Infectious diseases account for 26% of all deaths worldwide Leading cause of mortality in ressources limited countries Two-thirds of worldwide deaths in children <5 years old The Heavy Burden of Infectious Diseases % of deaths 18% 15% 31% 36% Pneumonia Diarrhoea Other infections Non infectious
  • « Emergence »: a global threat
      • Newly apparent pathogens: HIV, Ebola, H5N1, H1N1…
      • Rapidly increasing in incidence or geographic range : dengue, chikungunya, West Nile
      • Multidrug Resistant Pathogens :
      • NDM-1, E.Coli (EHEC)
      • Importance of zoonosis
      • Multidisciplinary approach
    Vectors Hosts Humans
  • A new vision of microbiology
    • Discovery of new viruses, new bacteria
    • The commensal microbiota : from homeostasis to disease
    • New technologies : deep sequencing, omics…
    • Molecular basis of host defense
    • Host genetic control
    • Biomarkers, Point of care, Pharmacogenomics
  • Medical and Scientific challenges
    • Transmission of infection (mechanisms, nosocomial…)
    • Emerging diseases ; zoonosis, human ecology, biodiversity
    • Resistance : Tuberculosis, Bacteria, MDR…
    • Infectious agents and non infectious diseases : cancer, cardiovascular, obesity, allergy, inflammation,…
    • Vaccination : new vaccines, immunity, SHS…
    • The big 3 : HIV, Tuberculosis, Malaria
  • IMMI: French Biomedical research Centers Institut Pasteur Paris Pitié Salpétrière Mondor/Bicêtre/Orsay/CEA/Saclay Bichat/St Louis Cochin/Cordeliers BIOPOLE Lyon-Grenoble IRT Lyon/Pasteur Institut Pasteur Lille Bordeaux Strasbourg INFECTIOPOLE Sud Marseille-Montpellier-Nice IHU
  • Microbiology and Infectious Diseases Key points: France 2011
    • Major Institutions : Institut Pasteur, Inserm, CNRS, IRD
    • Others : ANRS, CEA, CIRAD, INRA, INVS, Universities
    • 12% of French research forces : 300 teams, 2000 Scientists & Technical staff
    • 18% of French biomedical publications : 5000 publications per year
    • Translationnal and clinical research: 35 clinical units involved, including HIV and hepatits
    • Network of vaccine research centers
    • Large research network in ressources limited countries
  • Scientific Program (1)
    • 8.55 -11.30
    • Session 1 : UNDERSTANDING INFECTIOUS DISEASES: NEW MECHANISMS & PARADIGMS
    • Session 2 : NEW TARGETS AND TOOLS IN INFECTIOLOGY
    • 11.30 Transfer to Elysée Palace
    • 12.15 The President Sarkozy Lecture
    • 12.45 – 13.45 Buffet-Lunch
  • Scientific Program (2)
    • 14.00 – 14.30
    • Session 3 : NORTH-SOUTH PARTNERSHIPS:
    • POWERFUL RESEARCH TOOLS
    • 14.30 – 17.00 R&D Dating Session :
    • Twenty one companies will meet successively with 4 scientific teams representatives
    • This very short meeting allows to define whether a future in depth meeting should be scheduled in case of confirmed common interests
    • 17.15 Conclusion remarks: Pierre TEILLAC – Chairman of ARIIS
    • 17.45 Allocution by the Minister Mr Eric BESSON