MSDS Encapsome CL_Clodronate Liposome Control-Encapsula NanoSciences_2012
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MSDS Encapsome CL_Clodronate Liposome Control-Encapsula NanoSciences_2012

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Material Safety Data Sheet for Encapsome-CL the plain control liposome for Clodronate Encapsulated Liposome (Clodrosome)

Material Safety Data Sheet for Encapsome-CL the plain control liposome for Clodronate Encapsulated Liposome (Clodrosome)

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MSDS Encapsome CL_Clodronate Liposome Control-Encapsula NanoSciences_2012 MSDS Encapsome CL_Clodronate Liposome Control-Encapsula NanoSciences_2012 Document Transcript

  • ENCAPSULA NANOSCIENCES LLC MATERIAL SAFETY DATA SHEET Date Printed: 12/18/2011 Date Updated: 02/04/2006 Version 1.4Section 1 - Product and Company InformationProduct Name: PLAIN LIPOSOMES IN PHOSPHATE BUFFERED SALINEProduct Number: ENCP-2Brand: ENCAPSOME®Company Address: ENCAPSULA NANOSCIENCES LLC 441 DONELSON PIKE, SUITE 345 NASHVILLE, TN 37214, USATechnical Phone: 615-884-4442Fax: 615-250-8747Emergency Phone: 615-438-8553Section 2 - Composition/Information on IngredientSubstance Name CAS# SARA313PLAIN LIPOSOMES NONE NoIngredient Name CAS # Percent SARA313WATER 7732-18-5 >90 NoSODIUM CHLORIDE 7647-14-5 <5 NoPOTASSIUM CHLORIDE 7447-40-7 <5 NoDISODIUM PHOSPHATE 7558-79-4 <5 NoPOTASSIUM PHOSPHATE 7758-11-4 <5 NoL-α-PHOSPHATIDYLCHOLINE 8002-43-5 <5 NoCHOLESTEROL 57-88-5 <5 NoSection 3- Hazards IdentificationHMIS RATINGHEALTH: 0FLAMMABILITY: 0REACTIVITY: 0NFPA RATINGHEALTH: 0FLAMMABILITY: 0REACTIVITY: 0Potential Health EffectsInhalation May be harmful if inhaled. May cause respiratory tractirritation. 1Skin May be harmful if absorbed through skin. May cause skin irritation. PageENCAPSOME®-PBS WWW.CLODROSOME.COM
  • ENCAPSULA NANOSCIENCES LLC MATERIAL SAFETY DATA SHEETEyes May cause eye irritation.Ingestion May be harmful if swallowed.For additional information on toxicity, please refer to Section 11.Section 4 - First Aid MeasuresORAL EXPOSURE If swallowed, wash out mouth with water provided person is conscious. Call a physician.INHALATION EXPOSURE If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.DERMAL EXPOSURE In case of contact, immediately wash skin with soap and copious amountsof water.EYE EXPOSURE In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.Section 5 - Fire Fighting MeasuresFLASH POINT N/AAUTOIGNITION TEMP N/AFLAMMABILITY N/AEXTINGUISHING MEDIA Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.FIREFIGHTING Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Specific Hazard(s): Emits toxic fumes under fire conditions.Section 6 - Accidental Release MeasuresMETHODS FOR CLEANING UP Absorb on sand or vermiculite and place in closed containers for disposal. Ventilate area and wash spill site after material pickup is complete.Section 7 - Handling and Storage 2 PageHANDLINGENCAPSOME®-PBS WWW.CLODROSOME.COM
  • ENCAPSULA NANOSCIENCES LLC MATERIAL SAFETY DATA SHEET User Exposure: Do not breathe vapor. Do not get in eyes, on skin, on clothing.STORAGE Suitable: Keep tightly closed under an inert gas. Store in refrigeratorat 4 °C.Section 8 - Exposure Controls / Personal ProtectionENGINEERING CONTROLS Safety shower and eye bath. Mechanical exhaust required.PERSONAL PROTECTIVE EQUIPMENT Respiratory: Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection is desired, use multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges. Hand: Compatible chemical-resistant gloves. Eye: Chemical safety goggles.GENERAL HYGIENE MEASURES Wash thoroughly after handling. Wash contaminated clothing before reuse.Section 9 - PHYSICAL AND CHEMICAL PROPERTIESAppearanceWhite liquid dispersionSafety datapH7.4Melting pointN/ABoiling pointN/AFlash pointN/AIgnition temperatureN/A 3 PageLower explosion limitENCAPSOME®-PBS WWW.CLODROSOME.COM
  • ENCAPSULA NANOSCIENCES LLC MATERIAL SAFETY DATA SHEETN/AUpper explosion limitN/AWater solubilityN/ASection 10 - STABILITY AND REACTIVITYStorage stabilityCan be stored for one month under nitrogen or argon at 4 °C.Materials to avoidStrong acids, Strong basesHazardous decomposition productsHazardous decomposition products formed under fire conditions. - Carbonoxides, Oxides of phosphorus, Hydrogen chloride gas, Sodium oxidesSection 11 - TOXICOLOGICAL INFORMATIONROUTE OF EXPOSURESkin Contact: May cause skin irritation.Skin Absorption: May be harmful if absorbed through the skin.Eye Contact: May cause eye irritation.Inhalation: Material may be irritating to mucous membranes andupper respiratory tract. May be harmful if inhaled.Ingestion: May be harmful if swallowed.SIGNS AND SYMPTOMS OF EXPOSURETo the best of our knowledge, the chemical, physical, andtoxicological properties have not been thoroughly investigated.Section 12 - ECOLOGICAL INFORMATIONElimination information (persistence and degradability)N/AEcotoxicity effectsN/AFurther information on ecologyN/A 4Section 13 - DISPOSAL CONSIDERATIONS PageENCAPSOME®-PBS WWW.CLODROSOME.COM
  • ENCAPSULA NANOSCIENCES LLC MATERIAL SAFETY DATA SHEETProductObserve all federal, state, and local environmental regulations.Contaminated packagingDispose of as unused product.Section 14- TRANSPORT INFORMATIONDOT (US)Not dangerous goodsIMDGNot dangerous goodsIATANot dangerous goodsSection 15 - REGULATORY INFORMATIONOSHA HazardsNo OSHA HAZARDDSL StatusAll components of this product are on the Canadian DSL list.SARA 302 ComponentsSARA 302: No chemicals in this material are subject to the reportingrequirements of SARA Title III, Section 302.SARA 313 ComponentsSARA 313: This material does not contain any chemical components withknown CAS numbers that exceed the threshold (De Minimis) reporting levelsestablished by SARA Title III, Section 313.SARA 311/312 HazardsNO SARA HAZARDMassachusetts Right To Know ComponentsNo components are subject to the Massachusetts Right to Know Act.Pennsylvania Right To Know ComponentsLecithin AKA L-α-PhosphatidylcholineCAS-No. 8002-43-5Revision Date: 5Cholesterol PageCAS-No. 55-88-5Revision Date:ENCAPSOME®-PBS WWW.CLODROSOME.COM
  • ENCAPSULA NANOSCIENCES LLC MATERIAL SAFETY DATA SHEETNew Jersey Right To Know ComponentsLecithin AKA L-α-PhosphatidylcholineCAS-No. 8002-43-5CholesterolCAS-No. 55-88-5Revision Date:California Prop. 65 ComponentsThis product does not contain any chemicals known to State of Californiato cause cancer, birth, or any other reproductive defects.Section 16- OTHER INFORMATIONFurther informationCopyright 2009 Encapsula NanoSciences LLC license granted to makeunlimited paper copies for internal use only.The above information is believed to be correct but does not purport to beall inclusive and shall be used only as a guide. The information in thisdocument is based on the present state of our knowledge and is applicableto the product with regard to appropriate safety precautions. It does notrepresent any guarantee of the properties of the product. EncapsulaNanoSciences LLC shall not be held liable for any damage resulting fromhandling or from contact with the above product. 6 PageENCAPSOME®-PBS WWW.CLODROSOME.COM