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Molecular Genetics
         Understanding the Role of
         Molecules in Inheritance


Tuesday, March 9, 2010
Tuesday, March 9, 2010
Master Objectives:




Tuesday, March 9, 2010
Master Objectives:

          3.3.B.b	 Recognize that DNA codes for proteins,
              which are expressed as the her...
Master Objectives:

          3.3.B.b	 Recognize that DNA codes for proteins,
              which are expressed as the her...
Tuesday, March 9, 2010
DNA provides the CODE




Tuesday, March 9, 2010
DNA provides the CODE
             The sequence of nitrogen bases
         in DNA code for the building of protein




Tue...
DNA provides the CODE
             The sequence of nitrogen bases
         in DNA code for the building of protein




Tue...
DNA provides the CODE
             The sequence of nitrogen bases
         in DNA code for the building of protein

      ...
Each strand of DNA contains many
                 genes which each code for a
                         different protein p...
Each strand of DNA contains many
                 genes which each code for a
                         different protein p...
Protein is made by linking
                 AMINO ACIDS together




Tuesday, March 9, 2010
Protein is made by linking
                 AMINO ACIDS together




Tuesday, March 9, 2010
Every 3 bases in DNA codes
              for a specific amino acid




Tuesday, March 9, 2010
Every 3 bases in DNA codes
              for a specific amino acid




Tuesday, March 9, 2010
The sequence of amino acids
        gives the protein its properties




Tuesday, March 9, 2010
The sequence of amino acids
        gives the protein its properties




Tuesday, March 9, 2010
Structural proteins and
          enzymes are responsible
          for ALL of our inherited
          characteristics

Tu...
Examples:




Tuesday, March 9, 2010
Examples:




            antibodies


Tuesday, March 9, 2010
Examples:       keratin




            antibodies


Tuesday, March 9, 2010
Examples:                    keratin

                         hemoglobin


            antibodies


Tuesday, March 9, 2010
Examples:                    keratin

                         hemoglobin
                                      actin and
...
Examples:                       keratin

                         hemoglobin
                                          act...
The Big Picture




Tuesday, March 9, 2010
The Big Picture
    Central Dogma




Tuesday, March 9, 2010
The Big Picture

                         Protein Synthesis
    Central Dogma




Tuesday, March 9, 2010
The Big Picture

                         Protein Synthesis
    Central Dogma




Tuesday, March 9, 2010
Tuesday, March 9, 2010
Tuesday, March 9, 2010
Mutations are changes
          in the DNA that alter
          protein synthesis.


Tuesday, March 9, 2010
All mutation requires is
                         a change in 1 base pair...




Tuesday, March 9, 2010
All mutation requires is
                         a change in 1 base pair...




                         Chemicals


Tues...
All mutation requires is
                         a change in 1 base pair...




                         Chemicals

     ...
All mutation requires is
                         a change in 1 base pair...

        Nuclear Radiation

                 ...
All mutation requires is
                         a change in 1 base pair...

        Nuclear Radiation
                  ...
All mutation requires is
                         a change in 1 base pair...

        Nuclear Radiation
                  ...
"DNA makes RNA and RNA makes
                    proteins and proteins make us."
                              ~Francis Cr...
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Molecular Genetics

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Transcript of "Molecular Genetics"

  1. 1. Molecular Genetics Understanding the Role of Molecules in Inheritance Tuesday, March 9, 2010
  2. 2. Tuesday, March 9, 2010
  3. 3. Master Objectives: Tuesday, March 9, 2010
  4. 4. Master Objectives: 3.3.B.b Recognize that DNA codes for proteins, which are expressed as the heritable characteristics of an organism. (DOK: 1) Tuesday, March 9, 2010
  5. 5. Master Objectives: 3.3.B.b Recognize that DNA codes for proteins, which are expressed as the heritable characteristics of an organism. (DOK: 1) 3.3.B.e Identify possible external causes (e.g., heat, radiation, certain chemicals) and effects of DNA mutations (e.g., altered proteins which may affect chemical reactions and structural development). (DOK: 2) Tuesday, March 9, 2010
  6. 6. Tuesday, March 9, 2010
  7. 7. DNA provides the CODE Tuesday, March 9, 2010
  8. 8. DNA provides the CODE The sequence of nitrogen bases in DNA code for the building of protein Tuesday, March 9, 2010
  9. 9. DNA provides the CODE The sequence of nitrogen bases in DNA code for the building of protein Tuesday, March 9, 2010
  10. 10. DNA provides the CODE The sequence of nitrogen bases in DNA code for the building of protein The code (genes) are like a blueprint for constructing enzymes and cell parts Tuesday, March 9, 2010
  11. 11. Each strand of DNA contains many genes which each code for a different protein product Tuesday, March 9, 2010
  12. 12. Each strand of DNA contains many genes which each code for a different protein product Tuesday, March 9, 2010
  13. 13. Protein is made by linking AMINO ACIDS together Tuesday, March 9, 2010
  14. 14. Protein is made by linking AMINO ACIDS together Tuesday, March 9, 2010
  15. 15. Every 3 bases in DNA codes for a specific amino acid Tuesday, March 9, 2010
  16. 16. Every 3 bases in DNA codes for a specific amino acid Tuesday, March 9, 2010
  17. 17. The sequence of amino acids gives the protein its properties Tuesday, March 9, 2010
  18. 18. The sequence of amino acids gives the protein its properties Tuesday, March 9, 2010
  19. 19. Structural proteins and enzymes are responsible for ALL of our inherited characteristics Tuesday, March 9, 2010
  20. 20. Examples: Tuesday, March 9, 2010
  21. 21. Examples: antibodies Tuesday, March 9, 2010
  22. 22. Examples: keratin antibodies Tuesday, March 9, 2010
  23. 23. Examples: keratin hemoglobin antibodies Tuesday, March 9, 2010
  24. 24. Examples: keratin hemoglobin actin and myosin antibodies Tuesday, March 9, 2010
  25. 25. Examples: keratin hemoglobin actin and myosin antibodies pepsin and trypsin Tuesday, March 9, 2010
  26. 26. The Big Picture Tuesday, March 9, 2010
  27. 27. The Big Picture Central Dogma Tuesday, March 9, 2010
  28. 28. The Big Picture Protein Synthesis Central Dogma Tuesday, March 9, 2010
  29. 29. The Big Picture Protein Synthesis Central Dogma Tuesday, March 9, 2010
  30. 30. Tuesday, March 9, 2010
  31. 31. Tuesday, March 9, 2010
  32. 32. Mutations are changes in the DNA that alter protein synthesis. Tuesday, March 9, 2010
  33. 33. All mutation requires is a change in 1 base pair... Tuesday, March 9, 2010
  34. 34. All mutation requires is a change in 1 base pair... Chemicals Tuesday, March 9, 2010
  35. 35. All mutation requires is a change in 1 base pair... Chemicals UV Radiation Tuesday, March 9, 2010
  36. 36. All mutation requires is a change in 1 base pair... Nuclear Radiation Chemicals UV Radiation Tuesday, March 9, 2010
  37. 37. All mutation requires is a change in 1 base pair... Nuclear Radiation Mistakes Chemicals by the Cell UV Radiation Tuesday, March 9, 2010
  38. 38. All mutation requires is a change in 1 base pair... Nuclear Radiation Mistakes Chemicals by the Cell UV Radiation Carcinogens Tuesday, March 9, 2010
  39. 39. "DNA makes RNA and RNA makes proteins and proteins make us." ~Francis Crick Tuesday, March 9, 2010
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