• Share
  • Email
  • Embed
  • Like
  • Save
  • Private Content
Modifications to lecture on microbial control
 

Modifications to lecture on microbial control

on

  • 927 views

 

Statistics

Views

Total Views
927
Views on SlideShare
927
Embed Views
0

Actions

Likes
0
Downloads
45
Comments
0

0 Embeds 0

No embeds

Accessibility

Upload Details

Uploaded via as Adobe PDF

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
    Processing…
Post Comment
Edit your comment

    Modifications to lecture on microbial control Modifications to lecture on microbial control Presentation Transcript

    • CHEMOTHERAPEUTIC AGENTSMonday, January 23, 2012
    • CHEMOTHERAPEUTIC AGENTSMonday, January 23, 2012
    • CHEMOTHERAPEUTIC AGENTS Antibiotics are medicines used to treat infections caused by bacteria only Infections are usually caused by bacteria or viruses Antibiotics, therefore, do not cure all infections Many infections like the common cold, flu, mild sore throat or diarrhea are caused by virusesMonday, January 23, 2012
    • CHEMOTHERAPEUTIC AGENTS Antibiotics are medicines used to treat infections caused by bacteria only Infections are usually caused by bacteria or viruses Antibiotics, therefore, do not cure all infections Many infections like the common cold, flu, mild sore throat or diarrhea are caused by virusesMonday, January 23, 2012
    • Monday, January 23, 2012
    • WHAT IF ANTIBIOTICS WERE USED INCORRECTLY? No healing effect - If antibiotics are used for viral infections, there will be no effect on the illness Antibiotic resistance - This occurs when one antibiotic no longer works on a specific type of bacteria A stronger antibiotic will be needed to treat the infection caused by this resistant strain of bacteriaMonday, January 23, 2012
    • WHAT IF ANTIBIOTICS WERE USED INCORRECTLY? No healing effect - If antibiotics are used for viral infections, there will be no effect on the illness Antibiotic resistance - This occurs when one antibiotic no longer works on a specific type of bacteria A stronger antibiotic will be needed to treat the infection caused by this resistant strain of bacteriaMonday, January 23, 2012
    • ANTIBIOTIC MECHANISMSMonday, January 23, 2012
    • ANTIBIOTIC MECHANISMSMonday, January 23, 2012
    • RESISTANCEMonday, January 23, 2012
    • RESISTANCEMonday, January 23, 2012
    • Monday, January 23, 2012 RESISTANCE
    • Monday, January 23, 2012 RESISTANCE
    • Mechanisms of resistance Imipenem resistant Pseudomonas aeruginos Streptococcus pneumoniae resistance to Tetracycline penicillinsMRSA penicillinbinding protein Penicillins, PBP2A Cephalosporins Hawkey, P. M BMJ 1998;317:657-660Monday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE?Monday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE?Monday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE?Monday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE?Monday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE? Another factor that contributes to resistance is that when patients are prescribed antibiotics for a just cause, many do not finish their medication This allows resistant bacteria to survive more easily The practice of saving unused medication to treat themselves or others at a later date can also lead to resistant strainsMonday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE?Monday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE?Monday, January 23, 2012
    • DO YOU CONTRIBUTE TO RESISTANCE? Also contributing to antibiotic resistance is the widespread use of antibiotics to promote weight gain and to control disease in cattle, pigs, and chickens Forty to fifty percent of antibiotics produced are used in livestock feed This leads to an increase of resistant bacteria in these animals, which is then spread to humansMonday, January 23, 2012
    • THE CONSEQUENCES OF RESISTANCE: Ecology of pathogenesis Bacteria grow fast High population densities Great competition for resources Pathogen = normal bacterium that has gained access to a new resource through new genes --> Competitive advantageMonday, January 23, 2012
    • Monday, January 23, 2012
    • Monday, January 23, 2012
    • 12 Steps to Prevent Antimicrobial Resistance: Hospitalized Adults 12 Steps to Prevent Antimicrobial Resistance: Hospitalized Adults Use Antimicrobials Wisely Prevent Infection 5. Practice antimicrobial control 1. Vaccinate 6. Use local data 7. Treat infection, not 2. Get the catheters out contamination 8. Treat infection, not colonization Diagnose and Treat 9. Know when to say “no” to Infection Effectively vanco 3. Target the pathogen 10. Stop treatment when infection is cured or unlikely 4. Access the experts Prevent Transmission 11. Isolate the pathogen 12. Contain the contagionMonday, January 23, 2012
    • ANY QUESTIONS???Monday, January 23, 2012