Bioinformatics

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Bioinformatics

  1. 1. Workshop: Bioinformatics By Belinda Román Bioinformatics is the application of statistics and computer science to the field ofmolecular biology. A few things that we can do with the usage of bioinformatics aremapping and analyzing DNA and protein sequences, and aligning different DNA andprotein sequences to compare them . In this workshop, I learned where and how people areusing this area of sciences, and how it is contributing to investigations, making it easy forscientists to access data that is already known. In order for me to understand howbioinformatics works, I made a practice using the following database website:www.ncbi.nlm.gov. Here I looked first for the DNA sequence of the fibrinogen alpha chainin different species of organisms. In this step, I varied the search by also using accessionnumbers. Then, we learned how to translate a DNA sequence into a protein. In order to dothis, the database translates the sequence into an amino acid sequence and then into aprotein. Another interesting thing I did was the comparison of two sequences fromdifferent species. At the end, I was able to interpret the results of each of the differenttechniques used for searching and comparing sequences.

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