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Bragg Peak Particle Therapy Explained
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Bragg Peak Particle Therapy Explained

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  • 1. “The InternationalAgency forResearch onCancer projectsthat by 2030almost21.4 million newcases will bediagnosedannually…..”http://www.cbc.ca/health/story/2010/06/02/cancer-world-statistics.html Lester Lin ver. 1 10/4/2012
  • 2. An simple primer on varioustreatments for cancer such as Photons,Protons, and Carbon ions. Lester Lin v7 10/4/2012
  • 3. Every year, 10’s of millions of people willhear these words from their doctor. You Have Cancer Lester Lin ver. 1 10/4/2012
  • 4.  Typical cancer treatments:  Chemotherapy  Controlled poisoning of your body  Terrible side effects.  Hair loss  Nausea  Digestive tract Surgery  Invasive  Risk of infection  Damage to critical tissue  Scarring  Side effects such as impotence and incontinence for prostate cancer as an example. Lester Lin ver. 1 10/4/2012
  • 5. Typical cancer treatments: X-ray Radiation Therapy.  Exposure of healthy tissue to radiation  Negative Side effects CancerX-Ray Radiation bombarding tumor Tumor Lester Lin ver. 1 10/4/2012
  • 6.  Proton P Therapy Protons are propelled through an accelerator at 50% of the speed of light, then shot into the patient’s body aimed precisely at the tumor. Cancer Tumor Lester Lin ver. 1 10/4/2012
  • 7.  Proton P The Bragg Peak describes the characteristic of protons and ions to have a peak release in energy right before it comes to rest. This Therapy accounts for the amazing power to kill cancer cells, while minimizing bad radiation exposure to healthy tissue. There are only 30 Proton Therapy Centers around the world. Cancer Tumor Lester Lin ver. 1 10/4/2012
  • 8. X-Rays expose the healthytissue to maximum power,then decreases in energy onthe way to the tumor. Afterthe tumor, the energy is stilldissipating, and irradiatinghealthy tissue distally to thetumor.Protons are going throughhealthy tissue at very lowradiation levels and at highspeed, then reaches peakpower at the tumor,delivering peak killing power.The radiation level then dropsoff very quickly causing littledamage to healthy tissuedistally..Carbon Ions also have the Bragg Peak traits, but delivered at over 20x’sthe power of protons. Lester Lin ver. 1 10/4/2012
  • 9. Control Ion Pre-Linear Synchrotron System Source C Accelerator AcceleratorHow Ions are shot.The Ion Source produces carbon ions andfeeds it to thePre-Linear Accelerator which acceleratesthe carbon ions and feeds it to Beam LineThe Synchrotron Accelerator whichspeeds the carbon ions to 70% the speedof light and shoots them through theBeam Line to theThe Gantry, which aims these high speedcarbon ions at the patient’s cancerous Gantrytumor Treatment Couch and Chairwhile the patient is held very still in theTreatment Couch or chair to ensuremaximum possible accuracy. Lester Lin ver. 1 10/4/2012
  • 10. Control Ion SynchrotronSystem Source C Pre-Linear Accelerator Accelerator Beam LineThe ions rapidly peak inenergy when arriving atthe tumor and deliver Cancer Gantry Tumorthe killing power. Lester Lin ver. 1 10/4/2012
  • 11.  Carbon Ion Therapy vs. Proton Therapy Bragg Peak Systems, Inc.: A company that will build FDA approved Heavy Ion Therapy Systems. Protons come from Hydrogen molecules. P Carbon ions Carbon come from Carbon molecules. Many times, these are referred to as “Heavy Ions” because they are 20x’s 12x’s heavier than the protons, and cancer much more killing effective than energy protons against of cancer. Protons Lester Lin ver. 1 10/4/2012
  • 12. P •An angry wild elephant is charging at you. •Do you want the gun on Carbon the left? •or the one on the right to protect you? •The small gun can kill an elephant. • But the big one will do it 20 x’s faster and more the efficiently. cancer killing •Elephant = cancer. energy •Protons = small gun of •Carbon Ions = BIG gun. Protons Lin ver. 1 Lester 10/4/2012
  • 13. Protons typically deliver single breaks ofDNA strands, which leaves a chance for cancer cells to repair themselves. P P P P Lester Lin ver. 1 10/4/2012
  • 14. Carbon Ions deliver massive doublestrand breaks of DNA in the cancer Carboncells, making it impossible for them to repair themselves. Lester Lin ver. 1 10/4/2012
  • 15. X-Ray Radiation: Good Proton Therapy: Better Carbon Ion Therapy: Best Carbon Ions have shown the ability to kill tumors with 2 to 40x’s less treatment sessions than with Protons.  Consider what that means to a cancer victim.  Full treatments finished in 10 days instead of 40*  Less stress, and less “downtime” for the patient.  Less unnecessary exposure of healthy cells to radiation.  Financial savings for less travel and lodging during treatments, and less work missed Lester Lin ver. 1 10/4/2012
  • 16. 4 room Proton Center compared to 4 room Carbon Ion Center 1 year time frame each administering 36,000 sessions. 1 year comparison forecast of cured patients finishing treatments between a 4 room Carbon-Ion vs. Proton Center 4000 3500 3000 Protons Carbon Ion 2500 900 patients 3,600 patients completing completing 2000 treatments in treatments in one year. one year. 1500 •Higher Revenue 1000 •More Patients Treated. 500 0 Cured Patients Treatments x10 Proton Carbon-ion 2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments Lester Lin ver. 1 10/4/2012
  • 17. 4 room Proton Center compared to 4 room Carbon Ion Center 25 year time frame 25 year comparison forecast of cured patients finishing treatments between a 4 room Carbon-Ion vs. Proton Center 4000 3500 Over the next 25 years… let’s examine the long term effect: If you go with Protons, 67,500 less people will get treated for their cancer 3000 from your center. 2500 A Heavy Ion center, charging the same price to complete cancer treatments as 2000 a Proton center should generate 400 to 1000% more profit. On 1500 basis, compare generating 45 million USD yearly revenue as a Proton this center, (just for Proton treatments) or 180 million USD as a Heavy Ions Center… or how about DOUBLE THAT??? (which is a possibility) 1000 Over 25 years, 500 1.125 billion vs. 4.5 billion USD 0 Treated Patients Treatments x10 Proton Carbon-ion 2.5 patients per hour-12hrs. Per day-300 days per year. Avg. 40 total proton treatments vs. 10 total carbon treatments Lester Lin ver. 1 10/4/2012
  • 18. The Bragg Peak Systemsbusiness plan is to build a160 million USD productwith only 17 million of start-up capital, and no debt.Boeing invested over2 billion USD to develop the747 in the 1960’s to producea product that sold for Bragg Peak will produce the Heavy22 million USD each. Ion System with FDA approval in 4 years starting from the completion ofhttp://www.centennialofflight.gov/essay/Aerospace/Boeing_747/Aero21.htm funding. Lester Lin v7 10/4/2012 18
  • 19. Each year, an enemy on American soil kills over 550,000 Americans, andtakes over 1.5 million new hostages. the enemy is CANCER Lester Lin v7 10/4/2012 19
  • 20. The National Missile DefenseProgram:The projected cost of the program forthe years 2004 to 2009 will be$53,000,000,000 USD (53billion) for protection.We ask for investorparticipation of just $17million USD to bring the bestproven weapon against cancerinto a reality.Lester Lin v7 20 10/4/2012
  • 21. C C C C$50,000 USD Carbon Ion C CTreatment fee C C C C 10 Treatments in 2 Weeks @ $5,000 USD ea. = $50,000 40 Treatments in 8 Weeks @ $1,250 USD ea. = $50,000 P P P P P P P P P P P P P P P P$50,000 USD P P P P P P P P ProtonTreatment fee P P P P P P P P P P P P P P P P Lester Lin ver. 1 10/4/2012
  • 22. C Benefits for the Patient •Saved 7 weeks of time C •Saved 7 weeks of lodging expenses$50,000 USD •Saved 7 weeks of lost work-time Carbon Ion C •Reduced the stress of treatment by 7 weeks.Treatment fee C Benefits for the Medical Center •1000% more revenue per treatment. •Up to 10x’s more patients cured in equal time period.4 C Treatments in 1 Week @ $12,500 USD ea. = $50,00040 P Treatments in 8 Weeks @ $1,250 USD ea. = $50,000 P P P P P P P P P P P P P P P P$50,000 USD P P P P P P P P ProtonTreatment fee P P P P P P P P P P P P P P P P Lester Lin ver. 1 10/4/2012
  • 23. The future of treating a cancer patient ata much lower price point than currentfees can be accomplished with Heavy IonTherapy.This is of prime importance for countrieswith national health insurance.
  • 24. 2011 Medipolis, Japan 2012? Pavia, Italy 2012 Kiel, Germany History and Plans of 2013 Shizuoka, Japan Heavy Ion Centers Opening. 2014 Zhuhai , China 2014? Shanghai, China 2014? South Africa 2014? Austria CC Over 8,000 patients treated CC with Carbon Ions by 2010! C CC 2009 Heidleberg Germany 2010 Marburg Germany 2010 Gunma , Japan C C CC Main stream phase 2002 Hyogo Japan Carbon Ions are entering C the mainstream clinical 1997 GSI Germany usage phase with1994: Chiba, Japan C rapid acceleration of C Proving Heavy Ion Centers phase opening.
  • 25. 2011 Medipolis, Japan 5 years from now, Proton Centers 2012? Pavia, Italy will be fighting the stigma of being 2012 Kiel, Germany “YESTERDAY’S” technology. 2013 Shizuoka, Japan 2014 Zhuhai , China 2014? Shanghai, ChinaPlanners and decisionmakers will be 2014? South Africaquestioned, Why 2014? Austria C Cdidn’t they see thistrend coming?? Over 8,000 patients treated CC with Carbon Ions by 2010! C CC 2009 Heidleberg Germany 2010 Marburg Germany 2010 Gunma , Japan C C CC 2002 Hyogo Japan 5 years from now, those 1997 GSI Germany C who had the foresight to go with Carbon Ions1994: Chiba, Japan C today, will be admired as C Proving the strategic thinkers and Stage planners tomorrow.
  • 26. • Deliver 20x’s the cancer killing power ofThe Bragg Peak Systems Protons. Medical Advantage • Cure the Patient 4 to 10x’s faster • Financial earning potential over a Proton Center isThe Bragg Peak Systems staggering. Financial Advantage • Proton’s will find it hard to compete with Heavy Ion Centers in the future. • Shorter treatment times potentially 4 to 10x’s less.The Bragg Peak Systems • Less Stress for the patient Physically, Emotionally and Benefit to the Patient Financially. • Less unnecessary radiation exposure. • A Heavy Ion Center will provide maximum advantageThe Bragg Peak Systems to the general public by having the capability to treat Benefit to Society many multiples more patients than a Proton center with the same number of treatment rooms. Lester Lin ver. 1 10/4/2012
  • 27. The only company offering anupgradable Proton Therapy SystemThe only company with afirm commitment to deliver anFDA approved system from the onset.Bringing Heavy Ion systems to marketat an affordable price point. Lester Lin ver. 3 10/4/2012 27
  • 28. We hope you have caught our vision and inspiration andchoose Bragg Peak Systems as your partner for your FDAapproved Particle Treatment System. With all sincerity, the team from Lester Lin ver. 3 10/4/2012 JP 28
  • 29. We’re all about saving lives Lester Lin ver. 3 10/4/2012 29