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  1. 1. 1/23/2011<br />C2 BioTechnologies, LLC<br />1<br />By Larry Cosenza<br />
  2. 2. 1/23/2011<br />C2 BioTechnologies, LLC<br />2<br />Business Overview<br />R&D: Design enzymes for industry.<br />Goal: Manufacture enzymes for production of renewable energy.<br />Technology: Fusion Enzyme.<br />Seeking: Licensing and Commercial Partner.<br />
  3. 3. What We Do<br />Design enzymes for industrial process.<br />Design and construct more robust enzymes.<br />Design and construct enzymes to consolidate industrial bio-process.<br />1/23/2011<br />C2 BioTechnologies, LLC<br />3<br />
  4. 4. How Does This Help?<br />Robust enzymes can reduce variability in process… increasing product yield.<br />Consolidating bio-process reduces operating and consumables costs.<br />Each prototype fusion enzyme can be re-engineered: result in families of products.<br />1/23/2011<br />C2 BioTechnologies, LLC<br />4<br />
  5. 5. 1/23/2011<br />C2 BioTechnologies, LLC<br />5<br />Renewable<br />Feedstock<br />Where does C2 Biotechnologies fit in?<br />Energy<br />
  6. 6. 1/23/2011<br />C2 BioTechnologies, LLC<br />6<br />What are Enzymes?<br />Enzymes are proteins, which are produced by all living organisms. <br />Enzymes are responsible for a number of biological activities in plants, animals, human beings and microorganisms.<br />Enzymes are distinguishable from other proteins because of their catalytic activity.<br />Enzymes work by making or breaking chemical bonds.<br />
  7. 7. 1/23/2011<br />C2 BioTechnologies, LLC<br />7<br />How Do Enzymes Work?<br />Gluco-amylase<br />a - Amylase<br />
  8. 8. First Product Prototype<br />Amylase Fusion Enzyme<br />More robust <br />Active over wide range temperature<br />Actively converts starch into glucose<br />Simple bacterial production system<br />Target markets: ethanol, corn sweetener, fermentation.<br />1/23/2011<br />C2 Biotechnologies, LLC<br />8<br />
  9. 9. Second Technology in Development<br />Cellulase Fusion Enzyme<br />Consolidate bio-process<br />SBIR funded by Department of Energy<br />Target market: cellulosic ethanol<br />1/23/2011<br />C2 BioTechnologies, LLC<br />9<br />
  10. 10. 1/23/2011<br />C2 BioTechnologies, LLC<br />10<br />Industrial Enzymes Market<br />Current Enzyme Market $3.3 billion.<br />Currently ~13 billion gallons ethanol produced in U.S. nearly all from corn. <br />Global market expected to grow. <br />Amylase market ~20% of total or ~$660 million.<br />Cellulase market: growing…<br />
  11. 11. 1/23/2011<br />C2 BioTechnologies, LLC<br />11<br />Industrial Enzyme Pain Points<br />C2 BioTechnologies<br />Fits in here.<br />
  12. 12. 1/23/2011<br />C2 BioTechnologies, LLC<br />12<br />C2BioTechnologies:Right Time Right Place<br />Federal & State legislation mandating use of bio-fuels.<br />Current enzyme market growing.<br />New technology / new products.<br />New markets.<br />Fusion technology addresses industry pain points.<br />
  13. 13. Summary<br />R&D : Design and Construct Fusion Enzyme Technology for Industrial Use.<br />Products: Amylase & Cellulase Fusion Technologies<br />Target Markets: Energy, Food, Fermentation.<br />Goal: Manufacture Enzymes.<br />Seeking: Licensing and Commercial Partner.<br />1/23/2011<br />C2 BioTechnologies, LLC<br />13<br />

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