1/23/2011 C2 BioTechnologies, LLC 1 By Larry Cosenza
1/23/2011 C2 BioTechnologies, LLC 2 Business Overview R&D: Design enzymes for industry. Goal: Manufacture enzymes for production of renewable energy. Technology: Fusion Enzyme. Seeking: Licensing and Commercial Partner.
What We Do Design enzymes for industrial process. Design and construct more robust enzymes. Design and construct enzymes to consolidate industrial bio-process. 1/23/2011 C2 BioTechnologies, LLC 3
How Does This Help? Robust enzymes can reduce variability in process… increasing product yield. Consolidating bio-process reduces operating and consumables costs. Each prototype fusion enzyme can be re-engineered: result in families of products. 1/23/2011 C2 BioTechnologies, LLC 4
1/23/2011 C2 BioTechnologies, LLC 5 Renewable Feedstock Where does C2 Biotechnologies fit in? Energy
1/23/2011 C2 BioTechnologies, LLC 6 What are Enzymes? Enzymes are proteins, which are produced by all living organisms. Enzymes are responsible for a number of biological activities in plants, animals, human beings and microorganisms. Enzymes are distinguishable from other proteins because of their catalytic activity. Enzymes work by making or breaking chemical bonds.
1/23/2011 C2 BioTechnologies, LLC 7 How Do Enzymes Work? Gluco-amylase a - Amylase
First Product Prototype Amylase Fusion Enzyme More robust Active over wide range temperature Actively converts starch into glucose Simple bacterial production system Target markets: ethanol, corn sweetener, fermentation. 1/23/2011 C2 Biotechnologies, LLC 8
Second Technology in Development Cellulase Fusion Enzyme Consolidate bio-process SBIR funded by Department of Energy Target market: cellulosic ethanol 1/23/2011 C2 BioTechnologies, LLC 9
1/23/2011 C2 BioTechnologies, LLC 10 Industrial Enzymes Market Current Enzyme Market $3.3 billion. Currently ~13 billion gallons ethanol produced in U.S. nearly all from corn. Global market expected to grow. Amylase market ~20% of total or ~$660 million. Cellulase market: growing…
1/23/2011 C2 BioTechnologies, LLC 12 C2BioTechnologies:Right Time Right Place Federal & State legislation mandating use of bio-fuels. Current enzyme market growing. New technology / new products. New markets. Fusion technology addresses industry pain points.