Mining molecules from text and data

355 views

Published on

Published in: Technology, Education
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
355
On SlideShare
0
From Embeds
0
Number of Embeds
2
Actions
Shares
0
Downloads
3
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide
  • This is a conservative estimate based only on what is in PubMed Too much to read! Text mining used to extract relations Similar methods used to mine medical records and link diseases
  • Mining molecules from text and data

    1. 1. Mining molecules from text and data Lars Juhl Jensen
    2. 2. Reflect
    3. 3. augmented browsing
    4. 4. Pafilis, O’Donoghue, Jensen et al., Nature Biotechnology , 2009 O’Donoghue et al., Journal of Web Semantics , 2010
    5. 5. web services
    6. 7. STITCH
    7. 8. Kuhn et al., Nucleic Acids Research , 2010
    8. 9. >74,000 small molecules
    9. 10. >2.5 million proteins
    10. 11. 630 genomes
    11. 12. Gleevec
    12. 14. evidence types
    13. 15. primary experimental data
    14. 16. physical interactions
    15. 18. curated knowledge
    16. 19. drug targets
    17. 20. pathways
    18. 21. >10 km
    19. 22. literature mining
    20. 23. co-mentioning
    21. 25. NLP Natural Language Processing
    22. 27. integration
    23. 28. incomparable data
    24. 29. quality scores
    25. 30. calibrate vs. gold standard
    26. 31. Acknowledgments <ul><ul><li>Reflect </li></ul></ul><ul><ul><li>Sune Frankild </li></ul></ul><ul><ul><li>Heiko Horn </li></ul></ul><ul><ul><li>Evangelos Pafilis </li></ul></ul><ul><ul><li>Michael Kuhn </li></ul></ul><ul><ul><li>Reinhardt Schneider </li></ul></ul><ul><ul><li>Sean O’Donoghue </li></ul></ul><ul><ul><li>STITCH </li></ul></ul><ul><ul><li>Michael Kuhn </li></ul></ul><ul><ul><li>Damian Szklarczyk </li></ul></ul><ul><ul><li>Andrea Franceschini </li></ul></ul><ul><ul><li>Monica Campillos </li></ul></ul><ul><ul><li>Christian von Mering </li></ul></ul><ul><ul><li>Andreas Beyer </li></ul></ul><ul><ul><li>Peer Bork </li></ul></ul>
    27. 32. larsjuhljensen

    ×