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Disease Systems Biology

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  • Integration Automation Collaboration

Disease Systems Biology Disease Systems Biology Presentation Transcript

  • Disease Systems Biology Lars Juhl Jensen
  • signaling networks
  • proteomics
  •  
  • NetPhorest & NetworKIN
  • Miller, Jensen et al., Science Signaling , 2008
  • Linding, Jensen, Ostheimer et al., Cell , 2007
  • other modifications
  • association networks
  • STRING & STITCH
  • Kuhn et al., Nucleic Acids Research , 2010
  • data integration
  • Korbel et al., Nature Biotechnology , 2004
  • Jensen & Bork, Science , 2008
  • Letunic & Bork, Trends in Biochemical Sciences , 2008
  • more entity types
  • text mining
  • >10 km
  • Reflect
  • augmented browsing
  • Pafilis, O’Donoghue, Jensen et al., Nature Biotechnology , 2009
  • association mining
  • web services
  •  
  • patient records
  • text and registry data
  • drugs
  • side effects
  • diseases
  • patient trajectories
  • patient stratification
  •  
  • genotype vs. phenotype
  •  
    • Reflect
      • Sune Frankild
      • Heiko Horn
      • Evangelos Pafilis
      • Michael Kuhn
      • Reinhardt Schneider
      • Sean O’Donoghue
    • Patient records
      • Francisco Roque
      • Peter Bjødstrup Jensen
      • Henriette Schmock
      • Marlene Dalgaard
      • Massimo Andreatta
      • Thomas Hansen
      • Karen Søeby
      • Søren Bredkjær
      • Anders Juul
      • Thomas Werge
      • Søren Brunak
    ” we” are many people
    • STRING & STITCH
      • Damian Szklarczyk
      • Andrea Franceschini
      • Michael Kuhn
      • Milan Simonovic
      • Alexander Roth
      • Pablo Minguez
      • Tobias Doerks
      • Jean Muller
      • Manuel Stark
      • Samuel Chaffron
      • Chris Creevey
      • Philippe Julien
      • Jan Korbel
      • Berend Snel
      • Martijn Huynen
      • Christian von Mering
      • Peer Bork
    • NetPhorest & NetworKIN
      • Rune Linding
      • Heiko Horn
      • Martin Lee Miller
      • Gerard Ostheimer
      • Francesca Diella
      • Claus Jørgensen
      • Karen Colwill
      • Jing Jin
      • Pavel Metalnikov
      • Vivian Nguyen
      • Adrian Pasculescu
      • Marina Olhovsky
      • Michele Tinti
      • Lei Li
      • Marilyn Hsiung
      • Sirlester Parker
      • Jennifer Bordeaux
      • Thomas Sicheritz-
      • Pontén
      • Jes Alexander
      • Jin Gyoon Park
      • Stefan Knapp
      • Nikolaj Blom
      • Leona D. Samson
      • Rob Russell
      • Peer Bork
      • Shawn Li
      • Gianni Cesareni
      • Benjamin Turk
      • Søren Brunak
      • Michael Yaffe
      • Tony Pawson