Stem cell


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  • How are stem cells different than all other cells? “ Células madre,” Spanish for “stem cells,” reveals that these “mother” cells are responsible for certain cell lineages In culture, a stem cell will reproduce itself forever if given the right environment. Non-stem cells stop dividing after a certain number of divisions. (Draw on board) Stem cell divides into two daughter cells; one remains a stem cell, while the other turns into a more specialized cell Stem cells can travel around the body and turn into tissues that the body needs. (example get a cut, cells migrate over and replace damaged tissue) Now Laurel will talk more about differentiation.
  • Stem cell

    1. 1. Stem CellBy Lalit Mahajan
    2. 2. Definition• A cell that has the ability to continuously divide and differentiate (develop) into various other kinds of cells/tissues. #
    3. 3. Introduction• “Células madre” is a Spanish word for stem cell.• Stem cells are “mother” cells that give rise to all other cells in the body.• They are cells found in all multicellular organisms that can undergo mitosis to give rise to specialized cells, or more stem cells. #
    4. 4. Special Characteristics of all Stem Cells• Self-renewal (proliferation)- the ability of a stem cell to clone itself indefinitely by cell division.• Asymmetric cell division.• Relocation and Differentiation are abilities of stem cells to “migrate” to where they’re needed in the body and specialize into a particular type of mature cell. #
    5. 5. Cell division of stem cell #
    6. 6. Kinds of Stem CellsStem cell type Description Examples Cells from early Each cell can developTotipotent (1-3 days) into a new individual embryos Some cells of Cells can form anyPluripotent blastocyst (5 to (over 200) cell types 14 days) Cells differentiated, Fetal tissue, cordMultipotent but can form a number blood, and adult of other tissues stem cells #
    7. 7. Types of stem cell• Embryonic stem cells• Somatic/ adult stem cells #
    8. 8. #
    9. 9. Embryonic stem cells• come from embryos • This stage embryo is called a Blastocyst. (4-5 days old embryo)• can self-renew forever.• are pluripotent – they can differentiate to become almost every cell in the body.• Can be used for treatments for Paralysis, Diabetes, Alzheimer’s. #
    10. 10. Generates every cell in the body including the placenta and extra- Can form the entire embryonic tissues human being Can generate every cell in theCannot form the entire body except placenta and extra- human being embryonic tissues Become specific cell types are less flexible than above #
    11. 11. Somatic/ adult stem cells• found in adult tissue.• can self-renew many times.• are multipotent – they can differentiate to become only the types of cells in the tissue they come from. #
    12. 12. #
    13. 13. Potential uses of stem cells• Replacing damaged tissue• Studying human development• Testing new drugs• Screening toxins• Testing gene therapy methods #
    14. 14. Thank you #