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Secondary glaucoma
1. Secondary glaucomaSecondary glaucoma
associated with lens disordersassociated with lens disorders
glaucoma capsulareglaucoma capsulare
PseudoexfoliationPseudoexfoliation
syndromesyndrome
Exfoliative materialExfoliative material
Glaucoma due toGlaucoma due to
deposits of fibrillardeposits of fibrillar
basement membranebasement membrane
material on TBMmaterial on TBM
Treatment as in POAGTreatment as in POAG
2. Secondary glaucomaSecondary glaucoma
lens disorderslens disorders
phacomorphic glaucomaphacomorphic glaucoma
Swollen intumescentSwollen intumescent
lens causes pupillarylens causes pupillary
blockblock
Control of IOP followedControl of IOP followed
by lens extractionby lens extraction
3. Secondary glaucomaSecondary glaucoma
lens disorderslens disorders
phacolytic glaucomaphacolytic glaucoma
Due to micro leak of lensDue to micro leak of lens
protein in hypermature /protein in hypermature /
mature cataractmature cataract
Lens particle loadedLens particle loaded
macrophages block themacrophages block the
TBMTBM
Control of IOP and lensControl of IOP and lens
extractionextraction
4. Secondary glaucomaSecondary glaucoma
lens disorderslens disorders
phaco anaphylacticphaco anaphylactic
Associated with latentAssociated with latent
period during whichperiod during which
sensitization to lenssensitization to lens
protein occursprotein occurs
Seen more commonly inSeen more commonly in
young patientsyoung patients
Control of IOP and uveitisControl of IOP and uveitis
5. Secondary glaucomaSecondary glaucoma
lens disorderslens disorders
ectopia lentisectopia lentis
Secondary glaucoma dueSecondary glaucoma due
to congenital, traumatic orto congenital, traumatic or
spontaneous lensspontaneous lens
subluxation or dislocation.subluxation or dislocation.
Mechanism: pupillaryMechanism: pupillary
block, angle closure orblock, angle closure or
phacolyticphacolytic
6. Secondary glaucomaSecondary glaucoma
pigmentary glaucomapigmentary glaucoma
Young myopic patientsYoung myopic patients
Secondary open angleSecondary open angle
glaucoma due to pigmentaryglaucoma due to pigmentary
obstruction of TBMobstruction of TBM
Krukenburg’s spindleKrukenburg’s spindle
Retroillumination: radial spokeRetroillumination: radial spoke
like defects in the irislike defects in the iris
Treatment as in POAGTreatment as in POAG
7. Secondary glaucomaSecondary glaucoma
Neovascular glaucomaNeovascular glaucoma
Rubeosis iridis associated withRubeosis iridis associated with
glaucomaglaucoma
Seen in conditions:Seen in conditions:
Diabetic retinopathyDiabetic retinopathy
CRVOCRVO
Sickle cell retinopathySickle cell retinopathy
ROPROP
Treatment: Control of IOP,Treatment: Control of IOP,
photocoagulation with Trabphotocoagulation with Trab
10. Secondary glaucomaSecondary glaucoma
uveitisuveitis
Due to plasmoid aqueous andDue to plasmoid aqueous and
cells obstructing the anglecells obstructing the angle
In chronic due to posteriorIn chronic due to posterior
synechia/goniosynechiasynechia/goniosynechia
TreatmemtTreatmemt
control of IOPcontrol of IOP
control of uveitiscontrol of uveitis
23. Secondary glaucomaSecondary glaucoma
Steroid inducedSteroid induced
Secondary open angle glaucomaSecondary open angle glaucoma
Usually following topical therapy in high responders (marked rise ofUsually following topical therapy in high responders (marked rise of
IOP after about 6 wks of steroid therapy), occasionally occurs afterIOP after about 6 wks of steroid therapy), occasionally occurs after
systemic therapy alsosystemic therapy also
Deposition of mucopolysaccharides in the TBMDeposition of mucopolysaccharides in the TBM
Typically resembles POAGTypically resembles POAG
Judicious use of steroids is advocated to avoid above complicationJudicious use of steroids is advocated to avoid above complication
Discontinue steroids, IOP will get down in 10days-4 wks periodDiscontinue steroids, IOP will get down in 10days-4 wks period
Timolol maleate may be used if requiredTimolol maleate may be used if required
Surgery in intractable casesSurgery in intractable cases