Whether the strategy of short-term administration of small daily doses of prednisolone during infectious illnesses was effective in reducing annual relapse rates in patients with frequently relapsing nephrotic syndrome.
Mean difference 0.22 (95% CI 0.16, 0.28) (P=0.04).
Poisson regression, adjusted for occurrence of infections, daily administration of prednisolone during infections independently resulted in a 59% reduction in the rate of relapses (rate ratio, 0.41; 95% CI 0.3, 0.6).
Reduces frequency of relapses to less than 3 per yr
For every one out of six patients with frequent relapses