The relevance and efficacy of wireframing has been hotly debated for a few years now...but its just a tool like any other. Its how you use it that matters.
Leveraging a strong wireframing practice as an integral aspect of any creative process can have more impact than on the digital products you are creating. It can help shape your entire business.
Talk adaptation can be found here: http://www.idiom.co/progress-process-wireframe/