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Most state and local health departments are involved in on-going traditional disease surveillance and are beginning to access information through health information exchange with clinical partners. Biosurveillance initiatives offer the opportunity to leverage these existing initiatives while providing important data to protect community health. Building on these existing activities and relationships is key to the success of national initiatives such as BioSense Redesign and meaningful use of electronic health records as a component of the evolving nationwide health information network (NHIN). During this session/workshop, the National Association of County and City Health Officials (NACCHO) and the Association of State and Territorial Health Officials (ASTHO) in association with the Centers for Disease Control and Prevention will address discuss the BioSense redesign effort and provide opportunities for extended engagement of local and state health officials. This workshop encourages the participation of public health emergency responders, and local public health personnel involved in bio-surveillance for emergency preparedness and response within their jurisdictions.