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Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
Dysmen - Dysmenorrhea
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Dysmen - Dysmenorrhea

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  • The lunar cycle is based on the cycle of the moon typically being 28 days. 28 Days equals one month But in reality a month can be 28,29, 30, or 31 day.
  • Synergy of both Mefenamic acid and Dicyclomine help in erase the PAIN and decreases the SPASM.
  • Transcript

    • 1. DysmenMefenamic Acid & Dicyclomine Hydrochloride Tablets.Dispels Pain & Spasm FastDispels Pain & Spasm Fast
    • 2. Menstrual CycleMenstrual Cycle
    • 3. The Menstrual Cycle Days 1–4 The uterinelining is shed duringmenstruation.Days 5–13 An eggmatures in one of theovaries, and theuterine lining starts tothicken.EggEggMaturingEggDays 14–15 The ovaryreleases the mature eggduring ovulation.Days 16–22 The eggtravels through thefallopian tube to theuterus, and the uterinelining continues tothicken.Days 23–28 Theunfertilized egg entersthe uterus.
    • 4. THE LUNAR CYCLE• INTERVAL 28 DAYS• FLOW 5 DAYS• OVULATION DAY 14
    • 5. PHASES OF THE MENSTRUALCYCLE• MENSTRUATION• PROLIFERATION• OVULATION• SECRETORY
    • 6. PHASES OF THE MENSTRUALCYCLE• MENSTRUATION• PROLIFERATION• OVULATION• SECRETORY• DAY 1 to 5• DAY 6 to 13• DAY 14• DAY 15 to 28
    • 7. • VARIES• NEW FOLLICLE IS FORMING• THE UTERINE LINING IS SHEDDING• HORMONES ARE AT THEIR LOWEST• MUCUS IS LOW IN VOLUME &ELASTICITY,CLOUDY,THICK• TEMPERATURE IS NORMAL• SYMPTOMS: ANXIETY, HEADACHES,CRAMPS, NAUSEA, DEPRESSION, DIARRHEA,DECREASED LIBIDO
    • 8. • VARIES• FOLLICLE MATURING• UTERINE LINING BUILDING UP• HORMONES START TO RISE• MENSTRUAL SYMPTOMS SUBSIDING• FEELING PRETTY AND GOOD• LIBIDO INCREASING
    • 9. • FAIRLY CONSTANT time in your cycle• MATURE EGG LEAVES THE FOLLICLE• HORMONE PEAK• MUCUS IS HIGH VOLUME & ELASTICITY, THIN, CLEAR• TEMP IS LOW• SYMPTOMS: INCREASE SECRETIONS,NAUSEA, SHARP OR DULL PAIN, SPOTTING,
    • 10. • CONSTANT• EGG DEGENERATES• CORPUS LUTEUM REGRESSING• HORMONES STABLE- MODERATE• MUCUS IS LOW IN VOLUME & ELASTICY, THICK, CLOUDY• TEMP- SPIKES JUST AFTER OVULATION, THEN STABLIZES• SYMPTOMS: WEIGHT GAIN, BLOATING,SWELLING, BREAST TENDERNESS, ANXIETY,DEPRESSION,ANXIETY, HEAD ACHE, SPOTTING ,CONSTIPATION,ACNE
    • 11. What’s the impact?Women’s fluctuating hormones make us veryvariable in nature; men’s hormones are verysteady state and don’t fluctuate much at all.Basically it means that if you don’t like us today,wait-more than likely a female will improve in a fewdays…With men, if you don’t like them on day one, morethan likely they won’t change a whole lot.
    • 12. Prostaglandin
    • 13. ProstaglandinsActivation of the inflammatory response, production of pain,and feverWhen tissues are damaged, white blood cells flood to the siteto try to minimize tissue destructionProstaglandins are produced as a result. Blood clots formwhen a blood vessel is damagedA type of prostaglandin called thromboxane stimulatesconstriction and clotting of plateletsConversely, PGI2, is produced to have the opposite effect onthe walls of blood vessels where clots should not be formingPGE2 causes uterine contractions.
    • 14. ProstaglandinsActivation of the inflammatory response, production of pain,and feverWhen tissues are damaged, white blood cells flood to the siteto try to minimize tissue destructionProstaglandins are produced as a result. Blood clots formwhen a blood vessel is damagedA type of prostaglandin called thromboxane stimulatesconstriction and clotting of plateletsConversely, PGI2, is produced to have the opposite effect onthe walls of blood vessels where clots should not be formingPGE2 causes uterine contractions.
    • 15. Need of the DrugThat can cure pain and spasm in colic anddysmenorrhea cases
    • 16. DysmenMefenamic Acid & Dicyclomine Hydrochloride Tablets.Dispels Pain & Spasm FastDispels Pain & Spasm Fast
    • 17. MRP PTR PTS24.30 18.51 16.66MRP PTR PTS30.75 23.43 21.09
    • 18. PharmacologyMefenamic acid:analgesic, anti-inflammatory and antipyretic propertiesinhibits the enzymes of prostaglandin synthetase and alsoantagonizes the actions of prostaglandin at the receptorsitesdual mode of action of Mefenamic acid offers significantadvantages over other NSAIDs which merely inhibitprostaglandin synthesisThese effects may also be responsible for its effectivenessin the treatment of primary dysmenorrhoea
    • 19. DicyclomineDicyclomine is an anticholinergic. It is a competitive antagonistat muscuranic cholinergic neurons.Reduces the effect of acetylcholine, a chemical released fromnerves that stimulates muscles, by blocking the receptors foracetylcholine on smooth muscleDirect relaxing effect on smooth musclePrevent spasm in the muscles of the gastrointestinal tract inthe irritable bowel syndromeRelaxes the muscle and prevents spasms from occurring.Slightly reduce the production of stomach acid.
    • 20. PharmacologyBlocks action of AchInhibits parasympathetic actionsRelaxes smooth muscles of GIT, Biliary tract,Urinary Tract, UterusSynergy of Mefenamic acid andDicyclomine -Mefenamic acid erases pain and Dicyclominedecreases spasm.
    • 21. MOAIt also act as an antagonist atprostaglandin receptor sites. Ithas analgesic and antipyreticproperties with minor anti-inflammatory activityMefenamic acid inhibits theenzymes coyclooxygenase(COX-1) (COX-2) and reducethe formation of prostaglandin.Thus helps in relives the painMefenamic Acid
    • 22. PHARMACOLOGYMEFENAMIC ACID DICYCLOMINEIt is analgesic, anti inflammatory andanti pyretic property.It is anti cholinergic in propertyIt inhibits the enzymes andantagonizes the action ofprostaglandinIt decreases the effect of acetylcholineby blocking the receptors on smoothmusclesDual mechanism of action offeradvantages over NSAIDDirect relaxing effect on smoothmuscles prevents spasm of IBSThis effect may responsible fortreatment of DYSMENORRHOEAIt relaxes the muscles and preventspasm from occurring thus decreasesthe production of stomach acid.Synergy of both Mefenamic acid and Dicyclomine help in erase the PAIN anddecreases the SPASM

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