Dermopatología por Dra. Luxely Toledo

1. DERMATOPATOLOGÍA DRA. TOLEDO

2. Figure 25-1 A, The skin is composed of an epidermal layer (e) from which specialized adnexa (hair follicles, h; sweat glands, g; and sebaceous glands, s) descend into the underlying dermis (d). B, This projection of the epidermal layer (e) and underlying superficial dermis demonstrates the progressive upward maturation of basal cells (b) into cornified squamous epithelial cells of the stratum corneum (sc). Melanin-containing dendritic melanocytes (m) (and rare Merkel cells containing neurosecretory granules) and midepidermal dendritic Langerhans cells (lc) are also present. The underlying dermis contains small vessels (v), fibroblasts (f), perivascular mast cells (mc), and dendrocytes (dc), potentially important in dermal immunity and repair.

7. NEVUS NEVOCELULAR DE LA UNIÓN

9. NEVUS NEVOCELULAR TIPO COMPUESTO

18. NEVUS DISPLÁSICO

21. ETAPAS DE LA PROGRESIÓN TUMORAL EN LOS NEVUS DISPLÁSICOS

24. MELANOMA MALIGNO

27. MELANOMA MALIGNO

29. MELANOMA MALIGNO

31. FASE DE CRECIMIENTO RADIAL

33. FASE DE CRECIMIENTO VERTICAL

36. CÉLULAS MALIGNAS DEL MELANOMA

41. MÉTODO DE BRESLOW ESPESOR (%) SUPERVIVENCIA A 8 AÑOS (%) <0.76 93.2 0.76-1.69 85.6 1.70-3.60 59.8 >3.60 33.3

44. CARCINOMA ESCAMOSO

50. CARCINOMA ESCAMOSO

52. CARCINOMA ESCAMOSO

55. CARCINOMA BASOCELULAR

57. CARCINOMA BASOCELULAR

64. CARCINOMA BASOCELULAR