Heart Structure• Hollow• Located within the mediastinum of the thorax.• Base is attached to several large blood vessels.• Distal end extends downward and to the left forming a blunt apex at the fifth intercostal space.
Pericardium orpericardial sac coversthe heart.
The inner layer of the pericardium is called the visceral pericardium (epicardium)which covers the heart.The parietal pericardium forms the inner lining of the fibrous pericardium.The fibrous pericardium is tough and composed of mostly connective tissue.Between the layers is the pericardial cavity which has pericardial fluid thatlubricates the membranes to reduce friction when the heart moves.
The heart consists of three different layers
Mitral Valve Closed
Mitral Valve Open
Semilunar Valve Function
Tricuspid ValveChordae Tendineae
Circumflex artery – supplies the blood to the walls of the left atrium and left ventricle.Left anterior descending artery – supplies the walls of both ventricles.Posterior interventricular artery – supplies the walls of both ventricles.Marginal artery – supplies the walls of the right atrium and right ventricle.
Heart Actions• Atrial systole is when the atria contract while the ventricles relax which is called ventricular diastole.• Thus systolic and diastolic blood pressure.• This series of contraction and relaxation is called a cardiac cycle.
Heart Sounds• “Lubb” heart sound occurs during the ventricular contraction when the A-V valves are closing.• “Dubb” heart sound occurs during ventricular relaxation when the pulmonary and aortic valves are closing.• A heart murmur is when the heart valves fail to close completely causing leakage.
Sinoatrial NodeAtrioVentricular NodeAtrioventricular Bundle Purkinje FibersHeart Conduction System
Sympathetic & Parasympathetic Nervous Systems• Physical exercise, body temperature, and concentration of various ions affect heartbeat.• Branches of sympathetic and parasympathetic nerve fibers innervate the S-A and A-V nodes.• Parasympathetic impulses decrease heart action, sympathetic increases heart action.• Cardiac center in the medulla oblongata regulates autonomic impulses to the heart.
Effects of K+ & Ca2+• Potassium and calcium are two ions that influence heart action and are the most important.• Potassium affects the electrical potential of the cell membrane.• Calcium ions are needed more for cardiac muscles
Conditions• Hyperkalemia (excessive potassium ions) decreases the rate and force of cardiac contractions.• Very high amounts may block cardiac impulses.• Hypokalemia is low potassium and can cause an abnormal arrhythmia.• Hypercalcemia increases heart action causing a prolonged contraction.• Hypocalcemia depresses heart action.
Arteries are strong, elasticvessels adapted for carryingblood away from the heartunder high pressure.Three distinct layers:Endothelium – Inner mostlayer. Rich in elastic andcollagenous fibers. Called thetunica interna.Middle layer – Tunica media.Smooth muscle fibers, thicklayer of elastic connectivetissue.Outer layer – Tunica externa.Attaches the artery to tissues.Contains vasa vasorum that givesRise to capillaries
• Vasomotor fibers stimulate smooth muscle to contract, thus reducing the diameter of the vessel.• This is called vasoconstriction.• Vasodilation changes the diameter of the vessel that influences the blood flow and pressure.• Arterioles are microscopic continuations of arteries that give off branches called metarterioles that join capillaries.• If arteries are cut they spurt blood due to the high pressure of the heart.
Venules are microscopic vesselsThat continue from capillaries intoTo form veins.Veins have valves and arePushed back if blood beginsTo back up in a vein.Valves aid in the return ofBlood to the heart.Arterial blood loss will causea sympathetic nerve impulseto stimulate vein walls toreturn more blood to theheart to maintain bloodpressure.
Capillaries exchanges nutrients, gases, and metabolic by-products between theCapillary blood and tissue fluid.Diffusion provides the most important means of transport. The pathways dependon lipid solubilities.Filtration causes a net outward movement of fluid at the arteriolar end of acapillary.Osmosis causes a net inward movement of fluid at the venular end of a capillary.Plasma proteins generally stay in the blood.
Blood Pressure• Arterial blood pressure is produced by heart action; it rises and falls with phases of the cardiac cycle.• Systolic pressure occurs when the ventricle contracts; diastolic pressure occurs when the ventricle relaxes.• Heart action, blood volume, resistance to flow and blood viscosity influence arterial blood pressure.• Blood pressure is controlled by cardiac output.• The more blood that enters the ventricle the greater the stroke volume and the greater the cardiac output.
Venous Blood Flow• Not a direct result of heart action.• Skeletal muscle contraction, breathing movements and vasoconstriction influence the flow.• Venous constriction can increase venous pressure and blood flow.