This presentation illustrates the importance of routine immunization in its role of saving more lives than any other health service and reducing rates of preventable deaths. In order for this to continue, the foundation must be solid and stable for the structure of routine immunization system to endure all types of disease eliminations, interventions, and vaccination cycles. Countries are now making the transition from RED to REC to improve equity, access and complete immunization. Age groups targeted to receive vaccines include infants, young children, pre-adolescents, Women of child bearing age and expanded age groups during campaigns. Over the last 20+ years there has been a substantial increase in NVI.