Drug formulation, types and applications and its effectsDocument Transcript
Drug formulation, types and applications and its effects
The formulation of a drug is essential to the effectiveness of its delivery and has been specially selected
by the pharmaceutical manufacturer for the most positive outcome. Pharmaceutical formulations come
in a variety of types which can be divided into broad categories based on their mode of application.
These main categories include oral, topical, nasal, ophthalmic and intravenous formulations. Choosing
the right formulation of a new drug is based on a variety of factors, including absorption and drug
Some of the most common drugs come as oral formulations, which include capsules, tablets and
solutions. The solutions are typically used in situations where speed of delivery is a priority, such as
drugs that treat the symptoms of colds and coughs. An additional advantage of formulations of oral
solution is the ease of ingestion for sensitive or sensitive systems, such as children or the elderly. The
tablets are a standard formulation for water soluble drugs with stable structures due to their storage
and practice swallowed. Capsules are often used for drugs that absorb better in the mixed alcohol or
mixtures of glycerol.
Topical formulations are applied directly to the skin, while the ophthalmic formulations are given to the
eye. Nasal application, often used for sinus problems, is also used in situations that require faster
delivery. Intravenous injections but not as frequently used in commercial drugs are the preferred
method of delivery for patient already in the hospital or for some long-term treatments such as insulin.
active pharmaceutical ingredients
Determine the best formulation for a new drug is done through a complex series of formulation studies.
These studies examine a range of factors that contribute to the bioavailability of the drug, which is how
the body absorbs the drug. Some of the attributes that are essential to the proper formulation is the
particle size, solubility, and pH stability. Once the physical factors of the new drug were recorded,
commercial and consumer factors need to be addressed, including shelf life, appearance and ease of use
of the drug.
Specific targets for drug formulations may require unusual. Some drugs that are intended to be used in a
wide range of situations can come in a variety of formulations for ease of application. This is particularly
useful when the drugs are designed to be used with children such as liquid solutions are easier and
faster to ingest. Find the best formulation of a drug ensures that it will be as effective and efficient as
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