The document provides instructions for building molecular models of biomolecules through dehydration synthesis and hydrolysis. Students will construct models of glucose and then combine two glucose molecules through dehydration synthesis to form a disaccharide, modeling how glycogen is formed in the body. They will then reverse the process through hydrolysis, adding a water molecule back to separate the two glucose units, as occurs when glycogen is broken down into glucose. Students are asked to write definitions of dehydration synthesis and hydrolysis in their journal.

1. Building Biomolecules
Learning Goal:
I will build models of monomers of carbohydrates, lipids, and proteins. I will model dehydration
synthesis and hydrolysis. I will write a definition of dehydration synthesis and hydrolysis.
Key
Carbon: Black
Hydrogen: white
Oxygen: Red
Nitrogen: Blue
short white tubes are for single bonds
long white tubes are for double bonds
Carbohydrates
The monomer of a carbohydrate is called a monosaccharide. There are several types of
monosaccharides: glucose, fructose, sucrose, maltose, and lactose.
Where are these found?
glucose→ potatoes
fructose→ fruit
maltose→ sweet potatoes and turnips
lactose→milk
1. Today you will build a molecule of glucose. Use the key above and the drawing
below to construct your model.
2. Draw your glucose model in your journal.

2. 3. Take a Picture and place it in your folder
4. Now make a second model.
Disaccharide
You will now construct a disaccharide.
You are going to model the process that occurs in the body when glucose forms glycogen to be
stored in the liver for later use. Glycogen is a larger molecule than a disaccharide, but it will help
you understand the process.
1. Place both of your molecules on the table as below
2. Take a picture and place it in your folder
3. Remove the Hydrogen and stick from the OH on the left
4. Remove the OH on the right but leave the stick attached to the C
4. Combine the two monosaccharide at the remaining oxygen and carbon.
You have now formed a disaccharide!
5. Take the left-over H and OH and combine them.
6. What does this make?
7. This process is called dehydration synthesis.
8. WRITE your own definition of dehydration synthesis in your journal
Hydrolysis…
Now we will model the process that occurs when the body needs a quick supply of glucose.

3. For Example: The liver converts the glycogen into glucose for quick delivery into the blood- stream.
1. Reverse the process...add the H20 molecule back to the disaccharide to make two separate
glucose molecules.
This is hydrolysis!
2. Write your own definition of hydrolysis in your CJ.