Drug Innovation 2 (Handout)

Drug Innovation 2 (Handout) - Document Transcript

Drug Innovation 2.0 – Measure and improve !knowledge = people + information
Negative group dynamics
Encourage network building by helping people to connect, learn, to compete, to share, and to build trust. Let people be a social metric!
Information overload
Not keeping is easy!
Keeping is a challenge, but crowd-sourcing, “people-need”, and “people-centric” solutions can create knowledge networks.
Data silos
There are many challenges: standardization, semantics, security, integration, and legal aspects.
Helping patients requires building silo bridges!
General
Li & Bernoff; Groundswell - winning in a world transformed by social technologies2008http://www.forrester.com/Groundswell/book.html
Jones; Keeping Found Things Found (KFTF) : The Study and Practice of Personal Information Management2007http://www.keepingfoundthingsfound.com/book.html
Negative group dynamics
PNAS, 2005, Hirsch -- h-index; PLos ONE, 2009, various authors -- e-index, g-index , a-index, R-index.
Kittur, A.; Chi, E. H.; Pendleton, B. A.; Suh, B. & Mytkowicz, T.Power of the few vs. wisdom of the crowd: Wikipedia and the rise of the bourgeoisie, 2007.
Garnier, Rebuilding the R&D Engine in Big Pharma, Harvard Business Review, 2008.
“A better way of stimulating genuine innovation would be to reward scientists for ‘what they do, not for what the rest of the company does’.“
Information overload
Keeping Found Things Found (KFTF) book
http://miningdrugs.blogspot.com/2006/09/even-if-online-what-is-missing-for.html
http://miningdrugs.blogspot.com/2009/01/collaboration-bullseye-20-information.html
Data silos
Security http://jeremiahgrossman.blogspot.com/2008/12/its-unanimous.html
Privacy/Biobanking - European Science Foundation. Population Surveys and Biobanking, 2008.
Semantic web - chemmantis.com , reflect.ws
J.K. Wegner, 2009, Tibotec
Meet me online – joergkurtwegner, e.g. on LinkedIn, Twitter, Mining Drug Space, Facebook