An Introduction toSynthetic Biology“Hacking DNA for Fun and Profit”
1. what?2. applications3. the tech4. free and safe5. go hack
1. what?2. applications3. the tech4. free and safe5. go hack
Engineering vs Science
Understanding,             ModelsScience                  Engineering             Artifacts              (cells)
Synthetic Biology
Synthetic Biology         =GeneticEngineering++
1. Recombinant DNA2. PCR3. Automated sequencing
1. Recombinant DNA2. PCR3. Automated sequencing4. Automated construction5. Standardization6. Abstraction
SpecificationsTesting/Validation                           Design                      Standard                     Engine...
Specifications        Design           Modelling        Implementation       TestingStart!         Specifications         ...
1. what?2. applications3. the tech4. free and safe5. go hack
Biofuels
Bioremediation
Medicine
Space ISRU
1. what?2. applications3. the tech4. free and safe5. go hack
$1/bp, 4wk
e. coli: 4kyou and me: 3gbp
Standardzied  Assembly
CommonSignal Carrier
PolymeraseOperationsper Second
Characterization
Composition& Abstraction
http://www.ccbi.cam.ac.uk/iGEM2006/index.php/Description
http://www.ccbi.cam.ac.uk/iGEM2006/index.php/Description
1. what?2. applications3. the tech4. free and safe5. go hack
Legal Frameworks
Human Factors
1. what?2. applications3. the tech4. free and safe5. go hack
http://www.igem.org
http://parts.mit.edu
http://www.openwetware.org
Questions!
diybio.org    igem.org  parts.mit.eduopenwetware.org biohack.sf.net
Synthetic Biology at BarcampRochester3
Synthetic Biology at BarcampRochester3
Synthetic Biology at BarcampRochester3
Synthetic Biology at BarcampRochester3
Synthetic Biology at BarcampRochester3
Synthetic Biology at BarcampRochester3
Synthetic Biology at BarcampRochester3
Synthetic Biology at BarcampRochester3
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Synthetic Biology at BarcampRochester3

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A 30-minute overview of synthetic biology delivered April 2008.

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Synthetic Biology at BarcampRochester3

  1. 1. An Introduction toSynthetic Biology“Hacking DNA for Fun and Profit”
  2. 2. 1. what?2. applications3. the tech4. free and safe5. go hack
  3. 3. 1. what?2. applications3. the tech4. free and safe5. go hack
  4. 4. Engineering vs Science
  5. 5. Understanding, ModelsScience Engineering Artifacts (cells)
  6. 6. Synthetic Biology
  7. 7. Synthetic Biology =GeneticEngineering++
  8. 8. 1. Recombinant DNA2. PCR3. Automated sequencing
  9. 9. 1. Recombinant DNA2. PCR3. Automated sequencing4. Automated construction5. Standardization6. Abstraction
  10. 10. SpecificationsTesting/Validation Design Standard Engineering Implementation Practice Modelling The Imperial College of London, iGEM 2006
  11. 11. Specifications Design Modelling Implementation TestingStart! Specifications oscillator Based on Lotka-Volterra Modelling Lotka-Volterra Based on Quorum Sensing Modelling Full system Specifications test constructs Design test constructs Modelling Test construct Build test constructs Characterized test constructs Modelling characterized sys Build full system Characterized Full system Our Goal! The Imperial College of London, iGEM 2006
  12. 12. 1. what?2. applications3. the tech4. free and safe5. go hack
  13. 13. Biofuels
  14. 14. Bioremediation
  15. 15. Medicine
  16. 16. Space ISRU
  17. 17. 1. what?2. applications3. the tech4. free and safe5. go hack
  18. 18. $1/bp, 4wk
  19. 19. e. coli: 4kyou and me: 3gbp
  20. 20. Standardzied Assembly
  21. 21. CommonSignal Carrier
  22. 22. PolymeraseOperationsper Second
  23. 23. Characterization
  24. 24. Composition& Abstraction
  25. 25. http://www.ccbi.cam.ac.uk/iGEM2006/index.php/Description
  26. 26. http://www.ccbi.cam.ac.uk/iGEM2006/index.php/Description
  27. 27. 1. what?2. applications3. the tech4. free and safe5. go hack
  28. 28. Legal Frameworks
  29. 29. Human Factors
  30. 30. 1. what?2. applications3. the tech4. free and safe5. go hack
  31. 31. http://www.igem.org
  32. 32. http://parts.mit.edu
  33. 33. http://www.openwetware.org
  34. 34. Questions!
  35. 35. diybio.org igem.org parts.mit.eduopenwetware.org biohack.sf.net
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