Presentation for ENG 1020 class.

1. Human Genetic Manipulation Types and Applications

2. Somatic Modification Negative Genetic Engineering Not sperm or egg cells Used for gene therapy (healthy genes added to defective cells Non-inheritable Non-pathogenic virus (add desired genes which spread throughout the body)

3. Germ Line Manipulation Positive genetic engineering Manipulation of sperm, egg, or embryo cells Inheritable (all future generations) Can help improve physical and mental capacities of people

4. Resolvable Conditions (fully or partially) Alzheimer's Diabetes Lymphoma Cystic Fibrosis Muscular Dystrophy Achondoplasia Bipolar disorder Down Syndrome Huntington's disease Sickle Cell Anemia Color blindness Hemophilia (AND MORE!)

5. Treatments and Therapies Somatic Treatments Example- Diabetes Area specific treatment- pancreas (production) Blood treatment- whole body (efficiency)

6. Disease Prevention Germ Line isolation Example- DNA mapping -genome or chromosome anomalies -birth defects can be detected and corrected before conception -inherited immunities

7. Social Implications Extended longevity due to medical advancements. Decrease in healthcare expenses Crime investigation and Forensic technology

8. Sources Cited Gunderson, Martin. "Seeking Perfection: A Kantian Look at Human Genetic". Theoretical Medicine and Bioethics 2007: 87-102. Simmons, D. (2008) Genetic inequality: Human genetic engineering. Nature Education 1(1) Web. 1 Nov. 2009. Shanks, Pete. Human Genetic Engineering: A Guide for Activists, Skeptics, and the Very Perplexed. New York: Nation Books, 2005. Marks, Stephen. "Tying Prometheus down: The international law of human genetic manipulation". Chicago Journal of International Law . Chicago: University of Chicago Law School, 2002. Web. 1 Nov. 2009. Communications and Public Liaison Branch, "Genome.gov". National Human Genome Research Institute. 10/15/2009 <http://www.genome.gov/Research/> Web. 1 Nov. 2009.