Know your aptitude towards making custom extensions
Do you need support, or can you hack your own extensions?
Know your budget
Can you buy your way out of difficulty?
Recommendations What to Do... It depends... Budget Platform Access Native Technology Responds to Money Responds to Hacking Titanium ( Appcelerator) $$ x X X Rhomobile $$ x X X J2ME Polish $$ x X x Pure WebApp X Web, PhoneGap, Widget X x X Flash 10.1 (pre-beta) $$ X X