Inductively Coupled Plasma Mass spectrometry (ICP-MS)
Direct element information and quantification
Species identification via migration time
Low detection limit
High sensitivity and selectively
CE-ICP-MS Instrument Setup Quadrupole Mass Analyzer Detector Computer ICP Interface UV Detector Buffer / Sample Make-up Solution Capillary CE HV Power Supply
The CE-ICP-MS Interface Requirements: An electrical connection to the end of CE capillary High aerosol transport efficiency Low dead volume ICP Nebulizer Flow From CE Capillary CE Platinum Ground Electrode Make-up Sheath Flow O-ring
The Modified Concentric Nebulizer Nebulizer Gas In CE Capillary Stainless Steel Tube To Spray Chamber CE Capillary Stainless Steel Tube Nebulizer Inner Tube
- Reduce peak broadening due to the low dead volume.
- ICP-MS plasma may be extinguished.
- High cost.
- Difficult to use.
Pulsed Field CE-ICP-MS Instrument Setup V A Sample or Buffer UV Detector Current Voltage Probe Pulse Power Supply Capillary Interface Nebulizer To ICP Capillary with Silver Paint + G
Pulsed Field CE-ICP-MS Comparison of power consideration for a continuous versus pulsed CE Continuous s or ms, Pulsed DC 20kV, 40 A 0.8W Dc: 5kV, 10 A (0.05W) Pulse: 100kV, 0.2mA, 100 s, 200Hz (20W) Average: 0.45W t 1 t 2 Pulse DC