Mo W 11

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Mo W 11

  1. 1. Rotavirus
 Note the characteristic “wheel” shape of rotavirus particles from which its name is derived. •  Rotavirus
belongs
to
the
family
reoviridae.
 http://www.cdc.gov/ncidod/eid/vol4no4/ parashar.htm •  Caused
viral
gastroenteri6s:
 –  Results
in
low‐grade
fever,
severe
diarrhea,
and
vomi6ng.
 •  Treatment
typically
involves
oral
rehydra6on
therapy
un6l
the
virus
 runs
its
course.
 •  Rotavirus
is
an
RNA
virus;
the
virus
par6cle
contains
a
double‐ shelled
outer
capsid.
 •  Cool
Info:
 –  Gastroenteri6s
caused
by
rotavirus
is
more
common
and
more
severe
in
 children
than
adults,
with
infec6on
facilita6ng
future
immunity.
 –  An
es6mated
3
million
cases
annually
in
the
United
States,
but
less
than
 100
deaths;
the
rate
of
death
is
more
significant
in
less
developed
 countries.

  2. 2. West
Nile
Virus
 •  virus
family
Flaviviridae
 •  Single‐stranded
RNA,
polyhedral
protein
capsid,
enveloped
 •  West
Nile
virus
is
transmiLed
by
mosquitoes.
 •  Many
people
are
asymptoma6c,
some
only
experience
minor
 ones
such
as
a
skin
rash
and
headache;
most
people
recover
 without
treatment

 •  some
people
who
become
infected
with
West
Nile
virus
 develop
a
life‐threatening
illness
that
includes
inflamma6on
 of
the
brain
 –  No
drugs
available
 –  Suppor6ve
treatment,
an6‐inflamma6on
&
fluids

  3. 3. Ascaris
Lumbricoides
 •  In
kingdom
Animalia

 •  Responsible
for
the
disease
Ascariasis.
Causes
 poten6ally
severe
gastrointes6nal
complaints.
 •  infec6ons
in
humans
occur
when
an
ingested
 infec6ve
egg
releases
a
larval
worm
that
penetrates
 the
wall
of
the
duodenum
and
enters
the
 bloodstream.

 •  largest
of
the
intes6nal
nematodes
affec6ng
humans,
 measuring
15‐35
cm
in
length
in
adulthood.

 •  ¼
of
the
en6re
world
popula6on
is
infested…over
1
 billion


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