SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
HISTORY:
•

In addition to the...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
LESION/S AND DESCRIPTION
• cal...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Basic disease process/es
• Inf...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
DIAGNOSIS
• Hypertrophic osteo...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
BASIS/ BASES FOR THE DIAGNOSIS...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Differential diagnosis and the...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
• Hypertrophic Osteopathy (HO)...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
• Etiological information
The ...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Methods of transmission of the...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Other lesions present in the o...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Other lesions present in the o...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Clinical signs
• Anorexia
• De...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Clinical signs
• Anorexia
• De...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Cause/s of death not necessari...
SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Cause/s of death not necessari...
Hypertrophic Osteodystrophy
Hypertrophic Osteodystrophy
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Hypertrophic Osteodystrophy

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  • HOD and PANO are both associated with dysfunction in long bone development.  There is significant inflammation, edema and bone pain that can progress to deformity and bone necrosis.  
  • Hypertrophic Osteodystrophy

    1. 1. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE HISTORY: • In addition to the deformity evident in the clinical photo, this animal was lame and showed pain and warmth on palpation of the lower limb.
    2. 2. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE LESION/S AND DESCRIPTION • calcification • Hemorrhage • Metaphyseal enlargement
    3. 3. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Basic disease process/es • Inflammation • Necrosis
    4. 4. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE DIAGNOSIS • Hypertrophic osteodystrphy
    5. 5. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE
    6. 6. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE
    7. 7. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE BASIS/ BASES FOR THE DIAGNOSIS • History o Animal o Breed o Age o Specimen
    8. 8. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Differential diagnosis and the reasons for such. • Panosteitis It is a self-limiting developmental disease of young, large and giant breeds of dogs resulting in pain, lameness in one or more limbs.
    9. 9. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE • Hypertrophic Osteopathy (HO) It is a condition that affects long bones but is secondary to a primary thoracic or abdominal mass. The bony lesions are characterized by bilateral, symmetrical swellings affecting the distal extremities of the four limbs.
    10. 10. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE • Etiological information The cause of HOD is currently unknown
    11. 11. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Methods of transmission of the etiology and spread Genetic component is suspected.
    12. 12. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Other lesions present in the other organs not shown in the picture metastatic calcification of the aorta, endocardium, lungs, and kidneys at necropsy.
    13. 13. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Other lesions present in the other organs not shown in the picture metastatic calcification of the aorta, endocardium, lungs, and kidneys at necropsy.
    14. 14. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Clinical signs • Anorexia • Depression • pyrexia • weight loss.
    15. 15. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Clinical signs • Anorexia • Depression • pyrexia • weight loss.
    16. 16. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE
    17. 17. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Cause/s of death not necessarily euthanasia • Cardiac failure • Respiratory failure • Dehydration
    18. 18. SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Cause/s of death not necessarily euthanasia • Cardiac failure • Respiratory failure • Dehydration
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