Hypertrophic Osteodystrophy
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Hypertrophic Osteodystrophy

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  • HOD and PANO are both associated with dysfunction in long bone development.  There is significant inflammation, edema and bone pain that can progress to deformity and bone necrosis.  

Hypertrophic Osteodystrophy Hypertrophic Osteodystrophy Presentation Transcript

  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE HISTORY: • In addition to the deformity evident in the clinical photo, this animal was lame and showed pain and warmth on palpation of the lower limb.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE LESION/S AND DESCRIPTION • calcification • Hemorrhage • Metaphyseal enlargement
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Basic disease process/es • Inflammation • Necrosis
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE DIAGNOSIS • Hypertrophic osteodystrphy
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE BASIS/ BASES FOR THE DIAGNOSIS • History o Animal o Breed o Age o Specimen
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Differential diagnosis and the reasons for such. • Panosteitis It is a self-limiting developmental disease of young, large and giant breeds of dogs resulting in pain, lameness in one or more limbs.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE • Hypertrophic Osteopathy (HO) It is a condition that affects long bones but is secondary to a primary thoracic or abdominal mass. The bony lesions are characterized by bilateral, symmetrical swellings affecting the distal extremities of the four limbs.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE • Etiological information The cause of HOD is currently unknown
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Methods of transmission of the etiology and spread Genetic component is suspected.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Other lesions present in the other organs not shown in the picture metastatic calcification of the aorta, endocardium, lungs, and kidneys at necropsy.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Other lesions present in the other organs not shown in the picture metastatic calcification of the aorta, endocardium, lungs, and kidneys at necropsy.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Clinical signs • Anorexia • Depression • pyrexia • weight loss.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Clinical signs • Anorexia • Depression • pyrexia • weight loss.
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Cause/s of death not necessarily euthanasia • Cardiac failure • Respiratory failure • Dehydration
  • SPECIMEN: POST-MORTEM VIEW OF THE SAGITALLY-SPLIT DISTAL RADIUS OF A 3-MONTH OLD GREAT DANE Cause/s of death not necessarily euthanasia • Cardiac failure • Respiratory failure • Dehydration