Open Notebook Science and Malaria
Upcoming SlideShare
Loading in...5
×
 

Open Notebook Science and Malaria

on

  • 5,825 views

My presentation to Chemists Without Borders on September 6, 2007. I introduce the basics of the UsefulChem project and Open Notebook Science and why malaria is a particularly good target for Open ...

My presentation to Chemists Without Borders on September 6, 2007. I introduce the basics of the UsefulChem project and Open Notebook Science and why malaria is a particularly good target for Open Science. This includes the CombiUgi project and our collaborations with ChemSpider, Rajarshi Guha, Phil Rosenthal, Dan Zaharevitz and Tsu-Soo Tan. The final slide shows the presentation of our work on Second Life at a SciFoo Lives On session.

Statistics

Views

Total Views
5,825
Views on SlideShare
5,818
Embed Views
7

Actions

Likes
4
Downloads
94
Comments
4

1 Embed 7

http://www.slideshare.net 7

Accessibility

Categories

Upload Details

Uploaded via as Microsoft PowerPoint

Usage Rights

© All Rights Reserved

Report content

Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel

14 of 4 Post a comment

  • Full Name Full Name Comment goes here.
    Are you sure you want to
    Your message goes here
    Processing…
  • @BasarBilisimTeknolojileri Notebook very nice I would recommend to anyone
    Are you sure you want to
    Your message goes here
    Processing…
  • tq
    Are you sure you want to
    Your message goes here
    Processing…
  • Notebook
    thank you for sharing.
    useful.
    Are you sure you want to
    Your message goes here
    Processing…
  • Hi JC. I love the way you think about doing science. I have a brother-in-law doing cutting edge research in biomedical engineering and have discussed with him the 'open science' paradigm you talk about here. His reply is something along the lines of 'It would be interesting to see a senior researcher do something like that ... but it's just not done.'

    I wanted to follow many of the links in your presentation. Did you know that if you make them live links from within the original slideshow (Keynote or PowerPoint) that functionality carries over here to slideshare? You just have to keep the links in towards the middle of the page otherwise the 'forward' and 'backward' navigation functionality overrides the active links. Thought you might like to know. ;-)

    Cheers!
    Darren
    Are you sure you want to
    Your message goes here
    Processing…
Post Comment
Edit your comment

    Open Notebook Science and Malaria Open Notebook Science and Malaria Presentation Transcript

    • Open Notebook Science and Malaria Jean-Claude Bradley Drexel University September 6, 2007 Chemists Without Borders
    • Malaria is a Logical Application of Open Science
      • Very large problem: 300-500 million cases per year with one million deaths
      • Not a lucrative market: IP control less important
    •  
    • Open and Closed Science Traditional Lab Notebook (unpublished) Traditional Journal Article Open Access Journal Article Open Notebook Science (full transparency) CLOSED OPEN
    • Where is Science headed? WE ARE HERE
    • The Robot Scientist
      • Self-organizing redundant processes
      • Agents can participate with zero or near-zero cost (free hosted services – e.g. Google)
      • Fully Open Access (Read and Write)
      • Publication of all aspects of the scientific process: Open Source Science / Open Notebook Science
      How will this happen?
    • How can machines know what is important? Ask the humans
    • UsefulChem Blog
    • What chemists think is important in 2005
    • Find-A-Drug
    • Diketopiperazine Library Evolves to: on pot Ugi reaction/cyclization First iteration: Solid Support Synthesis
    • The Molecules Blog
    • The Experiments Blog
    • Comments from peers
    • The UsefulChem Wiki
    • Telling the story of the failures
    • Experiments moved to wiki
    • Experiment History
    • Experiment Edits
    • Third Party Time-Stamp on Experiment Versions
    • Monitoring experimental progress
    • How are people finding our experiments?
    • Molecules found by InChI
    • usefulchem.blogspot.com The blog as an integrative tool
    • usefulchem.wikispaces.com/Exp049 The wiki as the laboratory notebook
    • Graphical Mining of Data with JSpecView usefulchem.wikispaces.com/Exp070 (48h 7 min)
    • Processing Molecules on ChemSpider
    • The CombiUgi Project Focus on cheap starting materials and a product that precipitate easily from solution
    • Open Primary Research in Drug Design using Web2.0 tools (blogs, wikis, Second Life, mailing lists) Docking Synthesis Testing Rajarshi Guha Indiana U JC Bradley Drexel U Phil Rosenthal UCSF (malaria) Dan Zaharevitz NCI (tumors) Tsu-Soo Tan Nanyang Inst.
    • UsefulChem and Open Science in Second Life scifooliveson.wikispaces.com