Jean-Claude (Drexel U.) Philip Rosenthal (UCSF) Antony Williams (ChemSpider) UsefulChem: Open Notebook Science and Collaborative Drug Discovery Khalid Mirza (Drexel U.) Jiri Gut (UCSF) Rajarshi Guha (Indiana U.)

BLOG WIKI Mailing List GoogleDocs Architecture: Distributed, Interlinked and Redundant ChemSpider CDD FriendFeed Nature Precedings JoVE

Topic: Malaria Connections Phil Rosenthal, UCSF Malaria biology, screening Bradley Laboratory, Drexel Synthetic Chemistry Malaria data, global Rajarshi Guha, Indiana University Docking to pre-filter Ugi Library Bradley-Guha-Rosenthal-CDD Malaria Computational-Experimental Collaboration Goal: Accelerate drug discovery for malaria Bunin, Ekins etc Community Facilitators

Topic: Malaria

Connections

Where’s the Beef?

Link to Lab Notebook Page in Wiki

Link to Docking Results: Lists of SMILES in GoogleDocs (Rajarshi Guha)

Using ChemSpider to archive compound characterization

Drexel-UCSF Malaria Data Set within the Context of Other CDD Community Neglected Disease Data Sets

Ugi-4CC Product tested in P. Falciparum Cell Assay in Collaborative Drug Discovery (CDD) Database

Useful Chemistry Ugi Compound in CDD (public login: usefulchemistry, Password: cddcdd)

Open Access Data Easily Exported from CDD Database

Outcome of Guha-Bradley-Rosenthal collboration