Phospholipids

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Phospholipids

  1. 1. Lipids
  2. 2. Lipids <ul><li>Lipids are water insoluble macromolecules. </li></ul><ul><li>Fats and oils are triglycerides, composed of three fatty acids covalently bonded to a glycerol molecule by ester linkages. </li></ul>
  3. 3. Saturated lipids <ul><li>Saturated fatty acids have a hydrocarbon chain with no double bonds. </li></ul>
  4. 4. Unsaturated lipids <ul><li>The hydrocarbon chains of unsaturated fatty acids have one or more double bonds that bend the chain, making close packing less possible. </li></ul>
  5. 5. Phospholipids <ul><li>If one of the fatty acid chains in a triglyceride is replaced with a phosphate group (PO4) a phospholipid is produced </li></ul>
  6. 6. Phospholipids <ul><li>The Phosphate “HEAD” group is very negatively charged. It can dissolve easily in water by forming hydrogen bonds. It is hydrophilic (water loving). </li></ul><ul><li>The long fatty acid “Tail” chains are uncharged. They do not dissolve in water. They are hydrophobic (water hating). </li></ul>
  7. 7. Phospholipid bilayer <ul><li>In water, the interactions of the hydrophobic tails and hydrophilic heads of phospholipids generate a phospholipid bilayer that is two molecules thick. </li></ul><ul><li>The head groups are directed outward, where they interact with the surrounding water. </li></ul><ul><li>The tails are packed together in the interior of the bilayer. </li></ul>

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