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Genetics of human blood groups
 

Genetics of human blood groups

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    Genetics of human blood groups Genetics of human blood groups Presentation Transcript

    • Human Blood Groups
    • ABO Blood Group
      • There are 4 blood types in ABO blood group system.
      Blood Group Antigen A A B B AB A and B O Nil
    • Inheritance of Blood types
      • Human blood type is determined by co-dominant alleles.
      • There are three different alleles.
      • I A , I B and i
      • I A and I B are the dominant alleles and ‘ i ’ is the recessive allele.
        • Allele is one of the variant forms of a gene at a particular location, on a chromosome.
        • In an individual, one form of the allele (the dominant one) may be expressed more than another form (the recessive one).
    • Role of alleles
      • I A produces A antigen
      • I B produces B antigen
      • i produces no antigen (recessive allele)
      • I A and I B are co-dominant. That is, an individual with the genotype I A I B will produce both A and B antigens
    • Each of us has two blood type alleles. We inherit one blood type allele from our biological mother and one from our biological father. Genotype Blood Group A A B B AB O I A I A I A i I B I B I B i I A I B i i