A&P terminology introduced, a brief history of the study of anatomy, body systems, life processes, homeostasis, positive and negative feedback systems, directional terms and regions of the body terminology are introduced
2. The language of this course and Anatomy v. Physiology
Subdisciplines of Anatomy
Levels of Organization
Characteristics & life processes of the living human organism
Body systems and a brief history of the study of anatomy
Homeostasis and control mechanisms of homeostasis
Anatomical position
Body planes and directional terminology
Body regions and terminology
Body cavities and their membranes
Medical imaging methods/techniques for anatomical study
3. A & P Terminology
Greek // Latin
Cornerstone of learning anatomy
Prefix + Suffix = Term with a meaning
Gastro + ectomy = Gastrectomy
“Stomach” + “to cut out” = Stomach removal
4. Some prefixes / suffixes are remarkably similar
and easily confused
Brachi- = Arm
Brachy- = Short
Brady- = Slow
Tachy- = Fast
A & P Terminology
Alg- = Pain
Angi- = Blood vessel
5. Some word origins are easily confused
Gland (Aden-) Disease (Path-)
Organ (Viscer-) Poison (Tox-)
A & P Terminology
6. Some prefixes to get you started
Organs
Gastr- Stomach
Hepa- Liver
Nephr- Kidney
Entero- Instestine
Cerebro- Brain
Cardio- Heart
Pneumo- Lung
Derm- // Cut- Skin
A & P Terminology
Tissues
Chondr- Cartilage
Os- Bone
Myo- Muscle
Neuro- Nerves/ Nervous
Lip- // Lipo- Fat
7. Anatomy – the study of the structure of body
parts and their relationships to one another
Gross or macroscopic
Microscopic
Developmental
Physiology – study of the function of the
structures
Anatomy & physiology defined
8. Anatomy relates to physiology
Best (evolutionarily) adapted structures are
those that lead to best performance of
functions for life (survival).
What a structure does depends on its
specific form
9. Gross Anatomy
Regional – all structures in one part of the
body (such as the abdomen or leg)
Systemic – gross anatomy of the body
studied by system
Surface – study of internal structures as
they relate to the overlying skin
11. Specialized Branches of Anatomy
Pathological anatomy – study of structural
changes caused by disease
Radiographic anatomy – study of internal
structures as visualized by X ray, CT scan or
MRI, etc.
Molecular biology – study of anatomical
structures at a sub-cellular level
13. Levels of Structural Organization
Chemical – atoms combined to form molecules
Cellular – cells are made of molecules
Tissue – consists of similar types of cells
Organ – made up of different types of tissues
Organ system – consists of different organs that
work closely together
Organism – made up of the organ systems
14.
15. Anatomy – a historical perspective
Edwin – Smith Surgical
Papyrus
Egypt 1500 BCE
Written recognition of the
heart and its emanating
vessels, liver
spleen, kidneys, hypothal
amus, uterus and
bladder.
Also recognized
structures that carried air
17. Anatomy – a historical perspective
Humorism
Discredited theory adopted by
ancient Greek and Roman
physicians and philosphers
Commonly held view by European
Physicians until modern research in 19th cent.
18. Anatomy – a historical perspective
Claudius Galenius (Claude Galen)
Roman AD 129-200
Largely influenced by humorism, but
also stated importance of observation
and dissection
Copious amount of published work;
perhaps one of the most prolific writers
of antiquity
20. Anatomy – a historical perspective
Andreas Visalius 1514 - 1564
De Humani Corporis Fabrica Libri Septum 1543
Possible due to innovations in art and
printing techniques such as
ability to draw perspective and wood cut plates
21. Anatomy – a historical perspective
Leonardo Da Vinci 1452-1519
Techniques and understanding
years ahead of his time
Never published, his work
effectively lost until the 20th cent
Much of his work is owned
by the Queen of England
22. Life Processes
Metabolism (chem. process)
Catabolism – molecular decomposition
Anabolism – synthesis of molecules
Ingestion (food intake)
Digestion (decomp nutrient molecules)
Absorption (osmosis /diffusion)
Assimilation (nutrients form other needed substances)
23. Life Processes
Respiration (energy release)
Excitability (respond to environment)
Conductivity (carry/transmit effects of stimuli (i.e. nerve signal
transduction))
Growth (increase no. of cells)
Differentiation (stem cells specialize)
Reproduction (new cells or new organisms form)
24. Homeostasis
Maintenance of a relatively stable internal
environment in an ever-changing outside
world
Internal environment of the body is in a
dynamic state of equilibrium
Chemical, thermal, and neural factors
interact to maintain homeostasis
25. Homeostasis
Disruption to a controlled condition (i.e. blood
glucose level) stimulates a feedback system.
Feedback system composed of
Receptor
Control center
Effector
Nervous and Endocrine systems work to
maintain homeostasis // controlled conditions
26.
27.
28.
29. Feedback systems
Negative feedback system
Reverses a change in a controlled
system
Positive feedback system
Reinforces change in a controlled condition
Homeostasis mostly relies on neg feedback
Disease is failure of homeostatic control.
34. Directional Terms
Superior and inferior – toward and away
from the head, respectively
Anterior and posterior – toward the front
and back of the body
Medial, lateral, and intermediate – toward
the midline, away from the midline, and
between a more medial and lateral structure
35. Directional Terms
Proximal and distal – closer to and farther
from the origin of the body
Superficial and deep – toward and away
from the body surface
39. Body Planes
Sagittal – divides the body into right and left
parts
Midsagittal or medial – sagittal plane that
lies on the midline
Parasagittal – sagittal plane that does not
lie along the midline
40. Body Planes
Frontal or coronal – divides the body into
anterior and posterior parts
Transverse or horizontal (cross section) –
divides the body into superior and inferior
parts
Oblique section – cuts made diagonally
42. Body Cavities
Dorsal cavity contains the central nervous
system, has two subdivisions:
Cranial cavity is within the skull and encases
the brain
Vertebral cavity runs within the vertebral
column and encases the spinal cord
44. Body Cavities
Ventral cavity houses the internal organs
(viscera), and is divided into two
subdivisions:
Thoracic and Abdominopelvic cavities
45.
46. Body Cavities
Thoracic cavity is subdivided into pleural cavities,
the mediastinum, and the pericardial cavity
Pleural cavities – each houses a lung
Mediastinum – contains the pericardial cavity,
and surrounds the remaining thoracic organs
(thymus gland, esophagus, trachea, bronchi and large blood vessels)
Pericardial cavity – encloses the heart
47. Body Cavities
The Abdominopelvic cavity is inferior to the
thoracic cavity; separated by diaphragm
Abdominal cavity – contains the stomach, sm.
intestine, most of lg. intestine, spleen, liver, gall bladder,
pancreas
Pelvic cavity – lies within the pelvis and contains the
bladder, reproductive organs, cecum, appendix, sigmoid
colon and rectum
51. Serous membranes of the pleural cavity
Visceral pleura line surface of lungs
Parietal pleura line the chest wall
Serous membranes of the pericardial cavity
Visceral pericardium covers the heart
Parietal pericardium lines chest wall
Serous membranes of the abdominal cavity
Visceral / Parietal peritoneum
Serous fluid separates the serosae
52. Other Body Cavities
Oral and digestive – mouth and cavities of the
digestive organs
Nasal –located within and posterior to the nose
Orbital – house the eyes
Middle ear – contain bones (ossicles) that transmit
sound vibrations
Synovial – joint cavities
56. Medical Imaging
Allows for visualization of structures inside
the body. Helpful for diagnosis of disorders
Radiography (x-ray)
Computerized tomography (CT)
Digital subtraction angiography
Sonography
Magnetic resonance imaging (MRI)
Positron emission tomography (PET)
Editor's Notes
The study of anatomy begins at least as early as 1600 BCE, the date of the Edwin Smith Surgical Papyrus. This treatise shows that the heart, its vessels, liver, spleen, kidneys, hypothalamus,uterus and bladder were recognized, and that the blood vessels were known to emanate from the heart. Other vessels are described, some carrying air, some mucus, and two to the right ear are said to carry the "breath of life", while two to the left ear the "breath of death". The Ebers Papyrus (c. 1550 BCE) features a treatise on the heart. It notes that the heart is the center of the blood supply, with vessels attached for every member of the body. The Egyptians seem to have known little about the function of the kidneys and made the heart the meeting point of a number of vessels which carried all the fluids of the body – blood, tears, urine and semen. However, they did not have a theory as to where saliva and sweat came from.
Many medical texts by various authors are collected in the Hippocratic Corpus, none of which can definitely be ascribed to Hippocrates himself. The texts show an understanding ofmusculoskeletal structure, and the beginnings of understanding of the function of certain organs, such as the kidneys. The tricuspid valve of the heart and its function is documented in the treatiseOn the Heart.In the 4th century BCE, Aristotle and several contemporaries produced a more empirically founded system, based on animal dissection. Around this time, Praxagoras is credited as the first to identify the difference between arteries and veins, and the relations between organs are described more accurately than in previous works.The first use of human cadavers for anatomical research occurred later in the 4th century BCE when Herophilos and Erasistratus gained permission to perform live dissections, or vivisection, on criminals in Alexandria under the auspices of the Ptolemaic dynasty. Herophilos in particular developed a body of anatomical knowledge much more informed by the actual structure of the human body than previous works had been.
Humorism, or humoralism, is a now discredited theory of the makeup and workings of the human body, adopted by Ancient Greek and Roman physicians and philosophers, positing that an excess or deficiency of any of four distinct bodily fluids in a person directly influences theirtemperament and health. From Hippocrates onward, the humoral theory was adopted by Greek, Roman and Persian physicians , and became the most commonly held view of the human body among European physicians until the advent of modern medical research in the nineteenth century.The four humors of Hippocratic medicine are black bile (Gk. melanchole), yellow bile (Gk. chole), phlegm (Gk. phlegma), and blood (Gk. haima), and each corresponds to one of the traditional four temperaments
He traveled extensively, exposing himself to a wide variety of medical theories and discoveries before settling inRome, where he served prominent members of Roman society and eventually was given the position of personal physician to several emperors.Galen's understanding of anatomy and medicine was principally influenced by the then-current theory of humorism, as advanced by many ancient Greekphysicians such as Hippocrates. His theories dominated and influenced Western medical science for more than 1,300 years. His anatomical reports, based mainly on dissection of monkeys, especially the Barbary Macaque, and pigs, remained uncontested until 1543,
David is a masterpiece of Renaissance sculpture created between 1501 and 1504, by the Italian artist Michelangelo. It is a 5.17-metre (17.0 ft)[1]marble statue of a standing male nude. The statue represents the Biblical hero David, a favoured subject in the art of Florence.[2] Originally commissioned as one of a series of statues of prophets to be positioned along the roofline of the east end of Florence Cathedral, the statue was instead placed in a public square, outside the Palazzo dellaSignoria, the seat of civic government in Florence, where it was unveiled on 8 September 1504.Because of the nature of the hero that it represented, it soon came to symbolize the defense of civil liberties embodied in the Florentine Republic, an independent city-state threatened on all sides by more powerful rival states and by the hegemony of the Medici family. The eyes of David, with a warning glare, were turned towards Rome.[3] The statue was moved to the Accademia Gallery in Florence in 1873, and later replaced at the original location by a replica.
Andreas Vesalius (1514-1564), a native of Brussels, was descended from a family of prominent physicians in city of Wesel in the Duchy of Cleves. As a young man, he studied medicine in Montpellier and Paris and later moved to Louvain to teach anatomy. After serving as an army surgeon in France, he moved to Padua in 1537, where he became a professor of anatomy. In 1543, his famousDecorporishumanifabricalibriseptem (Seven books on the fabric of the human body) was published, for which he gained both fame and notoriety. That same year he was called to the court of Charles V, for whom he served as a court physician. He traveled Europe, from Brussels and Basel to Madrid and the court of Philip II of Spain. He later took up a pilgrimage to Jerusalem, but while in Cyprus he was called back to Padua to take an honored chair in anatomy. On his return, he was shipwrecked on the Greek island of Zante and died there on October 15, 1564.Vesalius' De corporishumanifabricalibriseptem is one of the most influential medical texts ever printed, not only because of the scientific methods used to produce it, but because of the artistic renderings of the anatomist's findings. Although he relied heavily upon Galen, at times translating his words exactly, Vesalius performed his own careful dissections and observed the body in great detail, confirming and refuting many of Galen's anatomical and physiological tenets. His peers reacted strongly to his decision to question Galen, and he received praise and condemnation
Although Leonardo is recognised as one of the greatest artists of the Renaissance, he was also one of the most original and perceptive anatomists of all time. The exhibition tells the story of his greatest challenge as he embarked upon a campaign of dissection in hospitals and medical schools to investigate bones, muscles, vessels and organs. Had Leonardo’s studies been published, they would have formed the most influential work on the human body ever produced. Some of his findings were not to be repeated for hundreds of years.On Leonardo’s death in 1519, his drawings remained unpublished and were effectively lost to the world until the 20th century. Instead, in 1543, the Flemish anatomist Andreas Vesalius published his treatise, De humanicorporisfabrica (‘On the fabric of the human body’) which became the most important work on anatomy ever published – to this day anatomical history is divided into pre- and post-Vesalian periods.
Dis-ease when all or part of body is not functioning normally in order to maintain homeostasis. local disease systemic disease symptoms – changes – are indications of disease (pain, nausea,) signs – changes – subjective (swelling, fever, rash) syndrome – several symptoms – signs of certain diseases epidemiology – study of why, where, and when diseases occur and how they are transmitted pharmacology – study of how drugs can treat disease diagnosis – distinguishing one disease from others, after medical history and exams are completed) measurements are frequently made in determination of disease
De humanicorporisfabricalibriseptem (On the fabric of the human body in seven books) is a textbook of human anatomy written by Andreas Vesalius (1514–1564) in 1543
Nine region designation used for anatomical study, quadrant designation is used to locate site of pain, tumor or other abnormality